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Keyword: folatereceptor

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  • Detecting cancer cells and parasites

    11/25/2012 7:36:23 PM PST · by neverdem · 5 replies
    Chemistry World ^ | 13 November 2012 | Rachel Cooper
    Scientists in Denmark have designed a new sensor to detect cells that over-express folate receptors, including cancer cells. Jaime Castillo-León from the Technical University of Denmark and colleagues' sensor consists of an electrochemical platform composed of graphene and peptide nanotubes with folic acid.Cancer cells have a high requirement for folic acid as it is necessary for their metabolism, so the cells have 500 times more folate receptors compared with a healthy cell, explains Castillo-León. The receptors are like antennas on the surface of the cell membrane that seek out folic acid. The cancer cells interact with the electrochemical platform,...