excerpted from medhelp; Low oxygen content of the blood can cause blue lips. This can be due to low counts or due to problems with oxygenation of the blood. It would be interesting to know what your blood oxygen saturation is during the episodes. Do they last for very long? If so then your brother may have time to come over to your house to check with a saturation monitor (many EMTs have this equipment). If it is low then your doctor would have to look for sources of low oxygen such as blood clots, sickle cell disease or other...