For the prevention of new-onset atrial fibrillation (AF) after isolated coronary artery bypass graft (CABG) surgery, giving potassium supplements only when levels dropped below the lower limit of normal was non-inferior to routinely supplementing potassium to the upper limit of normal, according to late-breaking research. "AF occurs in around one in three patients after CABG. In many centers, patients are given potassium supplementation after surgery in an effort to maintain serum levels in the high-normal range ('tight control') to prevent AF. However, there is no robust evidence to support this practice. TIGHT-K was an open-label, non-inferiority, randomized controlled trial. Patients...
