When a child with diabetic ketoacidosis (DKA) requires intensive care, clinicians often monitor blood ketone levels to determine whether treatment has successfully reversed the abnormal ketone production. Yet, the utility of blood ketone levels to diagnose DKA or determine whether a child's DKA has resolved have not been rigorously studied. Elise Tremblay, MD shows that a particular value of plasma beta-hydroxybutyrate (BOHB) can signal that DKA has clinically resolved and intensive treatment can stop. Widespread adoption of this defined endpoint could remove some of the uncertainty from monitoring DKA. It could potentially end intensive care at the right time—instead of...