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Differences in Pitt-Hopkins Syndrome (right) and a control (left) organoid. (Papes et al., Nature Communications, 2022) ================================================================== Scientists have uncovered changes in neurological structure that could underlie the autism spectrum disorder known as Pitt Hopkins syndrome, thanks to the help of lab-grown brains developed from human cells. Furthermore, the researchers were able to recover lost genetic functions through the use of two different gene therapy strategies – hinting at the possibility of treatments that could one day give those with the condition new options in improving their quality of life. Pitt Hopkins syndrome is a neurodevelopmental condition stemming from a...

World Autism Awareness Day is a tribute to the millions of Americans living with autism spectrum disorder (ASD). Their numerous triumphs over many and varied obstacles are a testament to the strength and resolve of the American spirit. We also extend our gratitude to all those who, through their unwavering dedication to supporting Americans with ASD, help empower them to thrive at home, in the workplace, and in their communities. As President, I am committed to ensuring all Americans with ASD can thrive and prosper. Last year, I was proud to sign into law legislation reauthorizing the Autism CARES Act,...

Contrary to what had been thought, young people with autism recognize and compare relationships among objects in scenes Children with autism have difficulty forming social relationships. But they discern relationships among objects in visual scenes surprisingly well, indicating a fundamental grasp of analogical reasoning, according to a new study. Youngsters diagnosed with autism, or autistic disorder, reason about the relations between objects and people on a par with kids free of any developmental problems, psychology graduate student Kinga Morsanyi of the University of Plymouth, England, and psychologist Keith Holyoak of the University of California, Los Angeles report in an upcoming...

Jersey scientists find a possible key to autism A team of New Jersey scientists believes it has found ways to detect biological risk factors for autism through simple urine and blood tests, a discovery that could lead to groundbreaking medical treatment for the neurological disorder. The team of 16 scientists, mostly drawn from the campuses of the University of Medicine and Dentistry of New Jersey, say their findings, the result of more than two years of study on how the body breaks down fatty acids, could be a breakthrough for what is the fastest-growing developmental disorder in the nation, with...