Ketamine Expert Claims Matthew Perry ‘Did Himself In’ Prior To Death
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Yahoo ^
| 12/18/23 | Kelly Coffey-Behrens
A ketamine specialist is weighing in on Matthew Perry's cause of death, claiming the actor "did himself in." Matthew
Perry had a large amount of the drug ketamine in his system at the time of death -- the same amount that would be used in general anesthesia. Toxicology testing found that ketamine levels in Perry's system were at 3540 ng/ml. For context, the report, obtained by The Blast, reads, “In monitored surgical-anesthesiology care, levels of general anesthesia are typically in the 1000-6000 ng/ml range.” In other words, he had a large amount of the drug in his system, enough to...
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Ketamine Can Rapidly Reduce Symptoms of PTSD and Depression, New Study Finds
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Yahoo! News ^
| Wed, November 8, 2023 | C. Michael White
The drug ketamine can reduce the symptoms of post-traumatic stress disorder, or PTSD, and symptoms of depression in patients as early as a day after injection. That
is the key finding of my team’s new meta-analysis, just published in the journal Annals of Pharmacotherapy. Ketamine is an anesthetic that is sometimes used as a substance of abuse but is increasingly being explored as a treatment for a range of mental health conditions. We analyzed six randomized controlled trials representing 259 patients with moderate to severe PTSD. In all trials, about half were injected with ketamine. The rest received either salt...
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Mind-altering ketamine becomes latest pain treatment, despite little research or regulation
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NEWS.YAHOO.COM ^
| 11/6/2023 | MATTHEW PERRONE
WASHINGTON (AP) — As U.S. doctors scale back their use of opioid painkillers, a new option for hard-to-treat pain is taking root: ketamine, the decades-old surgical drug that is now a trendy psychedelic therapy. Prescriptions
for ketamine have soared in recent years, driven by for-profit clinics and telehealth services offering the medication as a treatment for pain, depression, anxiety and other conditions. The generic drug can be purchased cheaply and prescribed by most physicians and some nurses, regardless of their training. With limited research on its effectiveness against pain, some experts worry the U.S. may be repeating mistakes that gave...
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Ketamine effective for treatment-resistant depression: Clinical trial (20% total remission in one month)
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Medical Xpress / University of New South Wales / The British Journal of Psychiatry ^
| July 13, 2023 | Colleen Loo et al
A low-cost version of ketamine to treat severe depression has performed strongly in a double-blind trial that compared it with placebo. Researchers
found that more than one in five participants achieved total remission from their symptoms after a month of bi-weekly injections, while a third had their symptoms improve by at least 50 percent. "For people with treatment-resistant depression—so those who have not benefitted from different modes of talk-therapy, commonly prescribed antidepressants, or electroconvulsive therapy—20 percent remission is actually quite good," Professor Colleen Loo says. "We found that in this trial, ketamine was clearly better than the placebo—with 20 percent...
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Magic Mushrooms. LSD. Ketamine. The Drugs That Power Silicon Valley.
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Wall Street Journal ^
| June 27, 2023 7:01 am ET | Kirsten Grind and Katherine Bindley
Magic Mushrooms. LSD. Ketamine. The Drugs That Power Silicon Valley. Entrepreneurs including Elon Musk and Sergey Brin are part of a drug movement that proponents hope will expand minds, enhance lives and produce business breakthroughs Elon Musk takes ketamine. Sergey
Brin sometimes enjoys magic mushrooms. Executives at venture-capital firm Founders Fund, known for its investments in SpaceX and Facebook, have thrown parties that include psychedelics. Routine drug use has moved from an after-hours activity squarely into corporate culture, leaving boards and business leaders to wrestle with their responsibilities for a workforce that frequently uses. At the vanguard are tech executives...
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Seizures of illicit party drug ketamine skyrocket 349% across United States
Initially designed for use as horse tranquilizer
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studyfinds.org ^
| 5/26/2023 | UNK
Seizures of the illicit party drug ketamine have skyrocketed by 349 percent in the United States over the last five years, new research reveals. This
significant increase has sparked alarm over the potential dangers tied to the escalating recreational use of this illegal substance, initially designed for use as a horse tranquilizer. The study by a team in New York indicates that the overall weight of ketamine seized in the U.S. escalated from 127 pounds in 2017 to roughly 1,550 pounds in 2022, marking an increase of over 1,100 percent. The hallucinogenic effects of ketamine have enhanced its popularity among...
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Murdered Cash App founder Bob Lee died on the operating table with alcohol, cocaine and ketamine in his system, autopsy shows:
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mail online ^
| 2 May 2023 | LEWIS PENNOCK
Hours before stabbing death he visited convicted drug dealer's home with suspect's SISTER Cash App founder Bob Lee died of stab wounds on the operating table and had drugs and alcohol in his system, his autopsy revealed Lee, 43, was murdered in the early hours of April 4 while visiting San Francisco
from Miami, where he moved last year with his family He had three stab wounds and underwent emergency treatment but was pronounced dead in the operating room of a San Francisco hospital Cash App founder Bob Lee died of stab wounds on the operating table and had drugs...
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New study reveals ketamine could be effective treatment for cocaine-use disorders (2X-4X remission rate)
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Medical Xpress / Case Western Reserve University / Addiction ^
| Feb. 20, 2023 | Zhenxiang Gao et al
As cocaine use continues to climb, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder. But
by seamlessly combining artificial intelligence (AI), human intelligence, clinical testing and computer analysis, researchers have unearthed an existing option that appears to hold promise. "Ketamine, a small synthetic organic molecule used clinically as an anesthetic and a depression treatment, was found to be associated with significant improvement in remission among people with cocaine-use disorders," said Rong Xu. "This study is a great example of addressing an intractable problem by the creative use of AI using different sources of data,"...
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Ketamine for Alcoholics Trial Goes to Next Stage
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BBC ^
| 12/14
A programme of therapy involving the drug ketamine will be made available to alcoholics in a research project. The
University of Exeter-led trial, with funding of £2.4m, will go ahead at seven NHS sites across the UK. The trial will look into whether a combination of ketamine and therapy could help alcoholics stay sober for longer. Prof Celia Morgan, the academic behind the research, said there was an "urgent need" for new treatments. The research will go ahead after a phase two trial showed ketamine and therapy treatment was safe and tolerable for heavy drinkers. An earlier study found participants...
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Ketamine may ease depression in as little as 4 hours by updating negative thoughts
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Medical News Today ^
| October 12, 2022 | Jessica Norris
-Depression is a mood disorder that affects many people and it can impact people’s beliefs and how they respond to information. -Ketamine
is a drug that is typically used as an anesthetic that is also used recreationally, however, its use as a treatment for depression is not fully understood. -A new study found that the administration of ketamine could help people develop more optimistic beliefs after receiving positive information. -Depression impacts millions of people in the United States alone, but the disorder can be challenging to treat. Some people do not respond well to the typical medications or therapies doctors...
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Mother, 33, smiles at her disabled daughter in last photo ‘before giving her a fatal dose of Ketamine’ as it emerges the deaths of her two OTHER girls were 'criminal acts'
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Daily Mail UK ^
| April 13, 2022 | Kaya Terry
A 33-year-old mother in Greece was pictured smiling at her disabled daughter in the last photo taken of the pair before 'giving her a fatal dose of Ketamine'. Roula Pispirigou was charged with killing her nine-year-old daughter Georgina after a test of her muscle tissue revealed the presence of the anesthetic drug,
which had not been administered by doctors. Georgina - who suffered from seizures in April 2021 that left her tetraplegic - died in January after spending eight months in hospital and nurses later confirmed that Pispirigou was alone with her daughter in the moments leading up to her...
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Ketamine Is Psychiatrists' Secret Weapon Against Depression. Here’s How it Works.
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MSN ^
| 7/9 | Abby Haglage
Ketamine, a drug once popular in the club scene, is now psychiatrists' secret weapon against depression. Perhaps
you've heard of it, either from celebrities' personal stories — such as former NBA player Lamar Odom — or through the many research studies currently underway to assess its effectiveness. What you may not know is how the drug works to relieve depression, and why it seems to help patients for whom all other treatments have failed. In that, you wouldn't be alone. Dr. Steven Levine, a board-certified psychiatrist who developed the protocol for the clinical use of ketamine in 2011, says scientists...
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Ketamine isn't an opioid and treats depression in a unique way
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Medical XPress ^
| July 31, 2019 | Johns Hopkins University School of Medicine
Ketamine has gotten a bad rap as an opioid when there's plenty of evidence suggesting it isn't one, Johns Hopkins experts say. They
believe this reputation may hamper patients from getting necessary treatment for the kinds of depression that don't respond to typical antidepressants. In a new paper, the researchers clarify the mechanism behind ketamine's mechanism of action in hopes of restoring the therapy's standing among health care professionals and the public. In March of this year, the U.S. Food and Drug Administration approved ketamine as a nasal spray to treat depression. "A study done late last year delivered a...
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FDA approves ketamine-like nasal spray for depression
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CNN ^
| 03/06/2019 | By Debra Goldschmidt,
Spravato is a nasal spray administered by an approved health care provider in a doctor's office or a medical clinic. It
may also be self-administered but only under the supervision of a care provider and cannot be taken home. "Because of [safety] concerns, the drug will only be available through a restricted distribution system and it must be administered in a certified medical office where the health care provider can monitor the patient," Farchione said. Depending on the severity of the patient's depression, it is given either once a week or once every other week. n. The drug is rapidly...
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Ketamine ‘cures’ suicidal woman of bipolar and severe depression
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metro.co.uk ^
A woman who was so depressed she wanted to crash her car into a tree and kill herself has been ‘cured’ of the condition with ketamine injections. Gabrielle
Idlet, 47, has suffered bipolar and severe depression since being molested by a family friend as a child, and feels her nervous system was overwhelmed by that trauma. The condition left her unable to work and saw her lose her home, with desperate Gabrielle trying almost all conventional and homeopathic treatments unsuccessfully. But she finally began to heal after signing up for eight ketamine shots at Dr Kathleen Wong’s Bridges to Wellbeing...
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Ketamine Clinic Opens in Midland
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newswest9.com ^
| Tuesday, December 5th 2017 | Jolina Okazaki
Depression takes an effect on a person's health. But
there's a type of treatment using ketamine that can put a stop to it. It's called Ketamine Infusion Therapy, a method healthcare professionals are using to not only ease the physical pain but the pain that no one sees. "What we did not realize until fairly recently, probably the past 10 years, that it works on glutamate receptors which are specific receptors to depression, PTSD, anxiety, those mood disorders," said Tammy Vaught, a certified registered nurse anesthetist with the Ketamine Clinic of West Texas. Vaught just opened the first ketamine clinic...
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'Club Drug’ Ketamine May Treat Depression, PTSD, Tinnitus
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www.laboratoryequipment.com ^
| Thu, 10/15/2015 - 9:05am | By Texas A&M University
Ketamine, a drug that is used as an anesthetic, may be a way to safely treat pain, PTSD, depression, and ringing ears (tinnitus), a new study suggests. Since
the drug is already approved by the Food and Drug Administration, it could potentially be available sooner and cost less. “It’s a lot more economical to repurpose drugs than to take a new drug and make it from scratch,” says David E. Potter, professor and chair of pharmaceutical sciences at Texas A&M University’s Rangel College of Pharmacy. “Not only in terms of dollars, but also in terms of time.” And because a...
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