Posted on 06/05/2019 10:33:08 AM PDT by RummyChick
Why would a drug company hide a potential market?
Why? The drug company probably made a deal with the insurance companies.
At $5,560.61 for the average price, insurance companies don’t want this.
Who are these "potens" and do they really represent a huge market?
bkmk
They probably have an Alzheimer drug in the works. The price of the arthritis drug is already set. Alz patients would want to buy it for that price, too. Pfizer knows people would gladly pay more for an Alz drug than an arthritis drug, so why sell a cheaper competitor. Just cover up their finding.
There is no advantage in spending money on a major study when you will not hit the 80% effective goal.
They also mess up shit, badly sometimes.
This is the fake news media weaponizing journalism to demonize “Big Pharma” in pursuit of socialize healthcare and government control of medical care and medical research.
But Pfizer’s scientific rationale is legit:
Enbrel is an anti-inflammatory and prior research on the effects of different types of anti-inflammatories on Alzheimer’s have found no evidence to suggest they work.
Plus the Enbrel molecules are too large to actually travel into the brain, further limiting its potential to work.
So the statistical correlation found in a database simply isn’t a big enough hook to spend millions of dollars on research that has no actual chance of success because there is no biological mechanism to explain how or why it might work.
Might is good only in horse shoes and handgrenades
To try and reengineer a new drug they can charge more for.
A very recent study said no NSAID had any affect on the progression of Alzheimers. They are all strong anti-inflammatory drugs.
Embrel is a completely different kind of drug called a biologic, which are expensive and have their own set of problems.
sorry that doesn’t make sense. what difference does it make to them if they sell a drug to treat it or sell a drug to prevent it. i think they’d sell MORE of the prevention.
Not true
If your mother was diagnosed with Alzheimer’s and was quickly going down hill...you MIGHT think about something that MIGHT work.
It is not your decision.
The first thing you will do when it doesn’t work is to sue them.
The potential benefits to the company are outweighed by the probable liability.
It wont work. Its that simple."
Not quite that simple.
""It would benefit the scientific community to have that data out there,'' said Keenan Walker, an assistant professor of medicine at Johns Hopkins who is studying how inflammation contributes to Alzheimer's. "Whether it was positive data or negative data, it gives us more information to make better informed decisions.''
There is a lot of evidence suggesting that peripheral or systemic inflammation may be a driver of Alzheimer's disease,'' said Walker, the Johns Hopkins researcher. It is a fair hypothesis that fighting inflammation outside the brain with Enbrel will have a similar effect inside the brain, he said.
"I don't believe Enbrel would need to cross the blood brain barrier to modulate the inflammatory/immune response within the brain,'' Walker said.
"There is increasing evidence that peripheral inflammation can influence brain function,'' said rheumatologist Christopher Edwards, of the University of Southampton in Britain."
https://expo.oregonlive.com/news/g66l-2019/06/80201a2d895306/pfizer-found-its-drug-appeared-to-reduce-alzheimers-risk-by-64-percent-why-didnt-it-do-anything-to-prove-it.html
At a minimum, Pfizer should release the data, or convince the FDA that clinical trials should begin.
What about Itanium ?
We had an extended support contract with hp and fujitsu and I had to support all that stuff.
I thought we should just buy out all the contracts
. I personally bought more HP ZX series stuff than probably any other single person in the world.
ARRGGG
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