Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

Seventeenth-Century Couple Left US Cancer Legacy
New Scientist ^ | 1-2-2008

Posted on 01/02/2008 7:27:00 PM PST by blam

Seventeenth-century couple left US cancer legacy

12:14 02 January 2008
NewScientist.com news service
Reuters and New Scientist staff

A married couple who sailed to America from England around 1630 may be the ancestors of thousands of people in the US at higher risk of a hereditary form of colon cancer who are alive today, researchers said on Wednesday.

US scientists traced a so-called founder genetic mutation found among two large families currently living in Utah and New York to the couple.

Cancer researchers at the Huntsman Cancer Institute in Utah say thousands of people across the country may have the mutation that spread widely as the couple's descendants branched over many generations.

"The fact that this mutation can be traced so far back in time suggests it could be carried by many more families in the United States than is currently known," says Deborah Neklason, who led the study. "In fact, this founder mutation might be related to many colon cancer cases in the United States."

Mystery cause Colorectal cancer is the third-leading cause of cancer death in the US. It will affect 153,000 Americans in 2008, according to the American Cancer Society, and will kill 52,000.

Family history, smoking and diet are all linked with colorectal cancer, but experts are still struggling to identify the causes that underlie most cases.

Less than 1% of these cases are due to this particular genetic mutation, estimates the study.

The US team first focused on the Utah branch of the family – numbering about 5000 people today – 14 years ago because its members had an unusually high risk of colon cancer.

Because the family was Mormon, the researchers were able to mine a wealth of genealogical information taken from detailed church records over the years that

(Excerpt) Read more at newscientist.com ...


TOPICS: News/Current Events
KEYWORDS: cancer; century; genetics; legacy; predisposition; seventeenth

1 posted on 01/02/2008 7:27:03 PM PST by blam
[ Post Reply | Private Reply | View Replies]

To: blam

And, so, in conclusion ... don’t vote for Mitt.


2 posted on 01/02/2008 7:31:07 PM PST by ClearCase_guy (The broken wall, the burning roof and tower. And Agamemnon dead.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: blam
How about the NAME?

Some of my ancestors immigrated from England to New York in the early 1600s. I sure would like to know the name.

3 posted on 01/02/2008 7:34:07 PM PST by AnAmericanMother ((Ministrix of Ye Chase, TTGC Ladies' Auxiliary (recess appointment)))
[ Post Reply | Private Reply | To 1 | View Replies]

To: AnAmericanMother

Their name was William and Jane AnAMericanMother ...uh oh....


4 posted on 01/02/2008 7:41:49 PM PST by There You Go Again
[ Post Reply | Private Reply | To 3 | View Replies]

To: There You Go Again

Ha! That’s not my maiden name! < g >


5 posted on 01/02/2008 7:44:44 PM PST by AnAmericanMother ((Ministrix of Ye Chase, TTGC Ladies' Auxiliary (recess appointment)))
[ Post Reply | Private Reply | To 4 | View Replies]

To: AnAmericanMother

Smith, perhaps?


6 posted on 01/02/2008 7:47:27 PM PST by PeaceBeWithYou (De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
[ Post Reply | Private Reply | To 3 | View Replies]

To: PeaceBeWithYou

Maybe if they had drank some tea or coffee?........


7 posted on 01/02/2008 7:56:21 PM PST by 9422WMR (clinton was responsible for 911)
[ Post Reply | Private Reply | To 6 | View Replies]

To: blam

Second the motion. What was the name? Surely the right to medical privacy doesn’t extend back to 1630.

One of my ancestors on my father’s side was Elder William Brewster, on the Mayflower. I don’t think he’s the guy they’re talking about, if this is mainly a New York/Utah thing.


8 posted on 01/02/2008 8:09:45 PM PST by Cicero (Marcus Tullius)
[ Post Reply | Private Reply | To 1 | View Replies]

To: blam

What’s the name or names of the families????

Why the mystery????


9 posted on 01/02/2008 8:18:07 PM PST by Tennessee Nana
[ Post Reply | Private Reply | To 1 | View Replies]

To: Cicero
My paternal grandmother's ancestors arrived on the Mayflower as well. My dad received copies of the "Mayflower Quarterly" from an organization made up of Mayflower descendants. I still haven't pinned down the exact person on the Mayflower, but that was required for the Mayflower Society to grant my dad's membership. His mom was also active with DAR (Daughters of the American Revolution). My mom's family claims lineage to John Alden and Priscilla Mullins. If you look at the genealogical records, there are thousands of descendants today.
10 posted on 01/02/2008 8:36:47 PM PST by Myrddin
[ Post Reply | Private Reply | To 8 | View Replies]

To: PeaceBeWithYou
Smith, perhaps?

The New York - Utah connection does bring Joseph Smith to mind, doesn't it?

11 posted on 01/02/2008 8:51:00 PM PST by RegulatorCountry
[ Post Reply | Private Reply | To 6 | View Replies]

To: There You Go Again

Heh. Good one!


12 posted on 01/02/2008 8:53:11 PM PST by Shortstop7
[ Post Reply | Private Reply | To 4 | View Replies]

To: RegulatorCountry

Yes, and he did die of Colon Cancer.


13 posted on 01/02/2008 8:58:50 PM PST by PeaceBeWithYou (De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
[ Post Reply | Private Reply | To 11 | View Replies]

To: Myrddin; Cicero
Not a Mayflower family of 1620. 1630 would be the Winthrop fleet, on which I had dozens of ancestors.

-ccm

14 posted on 01/02/2008 10:46:02 PM PST by ccmay (Too much Law; not enough Order.)
[ Post Reply | Private Reply | To 10 | View Replies]

To: ccmay

Could also have been the 140 folks on the Puritan ship Mary & John who also arrived here in 1630. They sailed from Plymouth, landed at Nantasket and founded the town of Dorchester, MA. I’m a direct descendant.


15 posted on 01/03/2008 5:44:31 AM PST by dorothy ( “The firm basis of government is justice, not pity.” —Woodrow Wilson)
[ Post Reply | Private Reply | To 14 | View Replies]

To: PeaceBeWithYou
Yes, and he did die of Colon Cancer.

Joseph Smith (LDS) was murdered in Liberty jail. He didn't die of colon cancer.

16 posted on 01/03/2008 7:12:24 AM PST by Myrddin
[ Post Reply | Private Reply | To 13 | View Replies]

To: Myrddin

You’re correct, I misread, it was his mother.


17 posted on 01/03/2008 10:51:45 AM PST by PeaceBeWithYou (De Oppresso Liber! (50 million and counting in Afganistan and Iraq))
[ Post Reply | Private Reply | To 16 | View Replies]

To: blam
All of the families that came on the Mayflower and in the early years of settlement are likely related.

One of my own ancestor’s, Jonathan Caulkard, arrived in Plymouth in 1630. My God bless him forever ( an all my immigrant ancestors) for coming to America.

18 posted on 01/03/2008 3:30:33 PM PST by wintertime (Good ideas win! Why? Because people are not stupid.)
[ Post Reply | Private Reply | To 1 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson