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A stroke of good luck for smokers (Brain addiction center found)
The Age ^ | Jan 26, 2007 | Radowitz

Posted on 01/26/2007 10:04:33 AM PST by The Raven

SCIENTISTS have pinpointed the source of nicotine addiction — a 2.5-centimetre-wide pleasure centre deep in the brain.

The insula, a small island in the cerebral cortex, has been described as a "platform for feelings and emotion".

Researchers found that smokers who suffered damage to this part of the brain were able to quit quickly and easily.

They suspect the insula may also be involved in other forms of addictive behaviour that keep people hooked on drugs or excessive eating.

Understanding the link could lead to new ways to deal with addiction.

The discovery emerged after US scientists learned of a heavy smoker whose dependency was broken after a stroke damaged his insula.

The man, who had smoked 40 cigarettes a day, quit immediately. He told researchers that his body "forgot the urge to smoke".

An investigation of 69 brain-damaged smokers then revealed 19 with insula injury. Of these, 13 had also given up, all but one without any difficulty. The researchers do not know why the six others failed to quit.

The study leader, Antoine Bechara, of the University of Southern California, Los Angeles, said: "One of the most difficult problems in any form of addiction is the difficulty in stopping the urge to smoke, to take a drug, or to eat for that matter.

"Now we have identified a brain target for further research into dealing with that urge."

The insula receives information from other parts of the body and is thought to help translate those signals into something subjectively felt, such as hunger, pain, or a craving.

In the 1990s, a neuroscientist, Antonio Damasio, first suggested that the insula was a platform for feelings and emotion.

"It's really intriguing to think that disrupting this region breaks the pleasure feelings associated with smoking," he said.

Compared with other brain regions, the insula has not attracted much attention from addiction researchers.

But some imaging studies have shown that the region is activated by drug-associated cues, such as the sight of people taking drugs, or drug-taking equipment such as spoons, syringes and "roll-up" paper.

Any anti-smoking treatment aimed at the insula would have to preserve the brain region's beneficial functions.

But Dr Bechara points out that the insula appears to be involved specifically with "learned behaviours", rather than fundamental drives necessary for survival. He believes it might be possible to target one without disrupting the other.

The findings were reported this week in the journal Science. Peter Stern, the journal's senior editor, said: "This kind of study is quite forward-looking. In addition to investigating a basic scientific mechanism underlying drug addiction, these authors have come up with innovative ideas about how we may be able to treat addiction and prevent relapse."


TOPICS: Culture/Society; News/Current Events
KEYWORDS: brain; health; medicine; research; science; smoking
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To: BipolarBob

I think that means that smokers are disabled / handicapped.
That means that the AWDA (Americans with Disabilitys Act) covers them. Smoke breaks, special acomodations are in order!


41 posted on 01/26/2007 11:22:57 AM PST by Frankss
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To: RobRoy

Me too! Post of the day, LOL.


42 posted on 01/26/2007 11:56:19 AM PST by olivia3boys
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To: L98Fiero
>> never heard of the stuff."

Link ==>

Chantix !!


43 posted on 01/26/2007 12:00:22 PM PST by The Raven (The right to be let alone is the underlying principle of the Constitution's Bill of Rights)
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To: RobRoy; vox_freedom

Ever notice how the real funny ones are in the first few posts ???


44 posted on 01/26/2007 12:01:27 PM PST by The Raven (The right to be let alone is the underlying principle of the Constitution's Bill of Rights)
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To: The Raven

okay-how long did you smoke? and did you enjoy smoking? what were your reasons for quitting?

Ive tried everything from hypnosis, pills, patches, gum etc.

I want to quit for health reasons and i think the biggest problem is for the most part, i enjoy it (but hate the cost, smell....)


45 posted on 01/26/2007 12:34:00 PM PST by OMalley (Without love, deeds, even the most brilliant, count as nothing. St. Therese, "the little flower")
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To: SW6906; Just another Joe; Madame Dufarge; Cantiloper; metesky; Judith Anne; lockjaw02; Mears; ...
Thanks for the ping.

And this is all well and good for people who WANT to quit smoking.  But they just don't get it!  Many of us actually enjoy smoking and have no desire to quit!

Will this ever stop???

\

46 posted on 01/26/2007 12:45:17 PM PST by SheLion (When you're right, take up the fight!!!!!)
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To: OMalley

>>okay

-how long did you smoke? 40 yrs

and did you enjoy smoking? Yes

what were your reasons for quitting? Don't want to die young


47 posted on 01/26/2007 12:49:48 PM PST by The Raven (The right to be let alone is the underlying principle of the Constitution's Bill of Rights)
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To: SheLion

>>Many of us actually enjoy smoking and have no desire to quit! Will this ever stop???

After taking Chantix - I didn't even remember why I liked it. That desire goes away.


48 posted on 01/26/2007 12:51:54 PM PST by The Raven (The right to be let alone is the underlying principle of the Constitution's Bill of Rights)
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To: The Raven

Thanks:)


49 posted on 01/26/2007 12:52:27 PM PST by OMalley (Without love, deeds, even the most brilliant, count as nothing. St. Therese, "the little flower")
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To: The Raven

Could be a job for Cyber-Knife!


50 posted on 01/26/2007 12:57:05 PM PST by Plutarch
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To: BipolarBob
How is this good luck? oh ok, I guess it's just assumed that every smoker really intends to quit.

This is one of those very rare occasions where I like to quote Andrew Dice Clay: "I still smoke, 'cause it pisses people off"

Cheers,
Lloyd

51 posted on 01/26/2007 1:00:54 PM PST by Lloyd227 (and may God bless Oriana Fallaci)
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To: The Raven
There are very few behaviors you can't stop by zapping various part of the brain.

None, in fact...

52 posted on 01/26/2007 1:16:41 PM PST by Interesting Times (ABCNNBCBS -- yesterday's news.)
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To: L98Fiero; The Raven; All
Here I sit with a Chantix prescription in hand from dr this am trying to decide whether to fill it and here you Chantix people are. Is Free Republic great or what?

Thank you for your positive comments on it - I'm off to get it filled.

53 posted on 01/26/2007 1:29:21 PM PST by daybreakcoming
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To: KoRn; daybreakcoming

Im wondering if both, or atleast one of you would be willing to FRmail me after your first week.

i just scheduled an appt, but its not for 3 weeks. would like to know how it works for you guys:)


54 posted on 01/26/2007 1:33:09 PM PST by OMalley (Without love, deeds, even the most brilliant, count as nothing. St. Therese, "the little flower")
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To: daybreakcoming

"I'm off to get it filled."

Good luck to you!


55 posted on 01/26/2007 1:35:28 PM PST by L98Fiero (A fool who'll waste his life, God rest his guts.)
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To: daybreakcoming

I just heard of it today, and I'm thinking of trying it. I might freepmail you in a couple of weeks and see how it's working out for you...


56 posted on 01/26/2007 1:35:35 PM PST by FLAMING DEATH (Open source is a good check on the artificial influence of monopolization.)
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To: OMalley
"Im wondering if both, or atleast one of you would be willing to FRmail me after your first week."

Will do.

57 posted on 01/26/2007 1:38:55 PM PST by KoRn
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To: KoRn

much appreciated!


58 posted on 01/26/2007 2:11:30 PM PST by OMalley (Without love, deeds, even the most brilliant, count as nothing. St. Therese, "the little flower")
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To: MARTIAL MONK

You may not be all that rare. I too quit several times over the years, often just because I never can do anything consistently.
The last time, it took will power to deny such a pleasure, but not a great deal of it.

Never really had what I'd call an addiction to it...or anything else.

They should put US in a study, eh? We could really fudge up the results.

Speaking of fudge, it's time for my IV.


59 posted on 01/26/2007 2:15:23 PM PST by Graymatter (...a cocoavore.)
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To: OMalley; FLAMING DEATH; KoRn
OK! Got it filled and ready to take my first dose in the am. In case you don't hear from me before you get ready - just FReepmail me and I will be glad to let you know how it is going for me. I am so optimistic (thanks to the encouraging testimony here) about this - even though I do/did enjoy smoking.

And KoRn - please let me know you are are doing with it.

60 posted on 01/26/2007 6:11:56 PM PST by daybreakcoming
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