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Common bacteria discovered in the eye linked to cognitive decline (Chlamydia pneumoniae)
Medical Xpress / Cedars-Sinai Medical Center / Nature Communications ^ | Feb. 2, 2026 | Kelsie Sandoval / Bhakta Prasad Gaire et al

Posted on 02/03/2026 4:37:55 PM PST by ConservativeMind

Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years and may aggravate Alzheimer's disease, according to a study. The discovery suggests this bacterium can amplify Alzheimer's disease and points to potential interventions including inflammation-limiting therapies and early antibiotic treatment.

The study shows for the first time that Chlamydia pneumoniae can reach the retina—the tissue lining the back of the eye—where it triggers immune responses linked to inflammation, nerve cell death and cognitive decline.

"Seeing Chlamydia pneumoniae consistently across human tissues, cell cultures and animal models allowed us to identify a previously unrecognized link between bacterial infection, inflammation and neurodegeneration," said Maya Koronyo-Hamaoui, Ph.D.

To conduct the study, researchers used advanced imaging, genetic testing and protein analysis to examine retinal tissue from 104 individuals, some with normal cognition, some with mild cognitive impairment and some with Alzheimer's disease.

They found significantly higher levels of Chlamydia pneumoniae in the retinas and brains of people with Alzheimer's disease than they found in people with normal cognition. The higher the bacterial levels detected, the more severe the brain changes and cognitive decline investigators found.

Higher levels of the bacterium were more common in people who carried the APOE4 gene variant, a known risk factor for Alzheimer's disease.

Investigators also studied human neurons in the lab and in laboratory mice with Alzheimer's disease. In both, infection with Chlamydia pneumoniae increased inflammation, nerve cell death and cognitive decline, showing the bacterium can accelerate disease processes. The infection also triggered production of amyloid-beta, the protein that accumulates in the brains of people with Alzheimer's.

The findings suggest that targeting chronic bacterial infection—and the inflammation it triggers—could represent a new treatment strategy.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: alzheimers; alzheimersdisease; apoe4; chlamydiapneumoniae; dementia; eye; eyebacteria; eyes; inflammation; sinusinfections

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Chlamydia pneumoniae can be a chronic condition and there are antibiotics that can cure it.

It may not reverse Alzheimer’s, but it might stop rapid progression.

1 posted on 02/03/2026 4:37:55 PM PST by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 02/03/2026 4:38:28 PM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Clap of the Eyes?


3 posted on 02/03/2026 4:42:02 PM PST by Salvavida
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To: Salvavida
Clap of the Eyes?

I may or may not have seen movies that demonstrate how this is transmitted.

4 posted on 02/03/2026 4:47:58 PM PST by Drew68
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To: Drew68
Everybody knows it spreads with a glance.

When two people's eyes meet across a crowded room......

BLAMO!

You have a pandemic.

5 posted on 02/03/2026 5:00:48 PM PST by Harmless Teddy Bear (The tree accused of killed Sonny Bono was planted.)
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To: ConservativeMind

I worked in a big city ER for years. Sometimes when a woman walked into a treatment room the nurses would look at each other and say “PID shuffle”. They could diagnose the woman just by the way she walked. IRRC Chlamydia is the same.


6 posted on 02/03/2026 5:06:46 PM PST by Gay State Conservative (Import The Third World,Become The Third World)
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To: ConservativeMind

Looking for love in all the wrong places.


7 posted on 02/03/2026 5:10:17 PM PST by Wilderness Conservative (Nature is the ultimate conservative)
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To: ConservativeMind

bkmk


8 posted on 02/03/2026 5:25:08 PM PST by Mark (DONATE ONCE every 3 months. Is that a big deal?)
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To: Salvavida

Wash your hands before rubbing your eyes. It might save you from going mad!


9 posted on 02/03/2026 5:25:41 PM PST by Nateman (Democrats did not strive for fraud friendly voting merely to continue honest elections.)
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To: Nateman

10 posted on 02/03/2026 5:30:41 PM PST by Kenny Bania (Ovaltine? Why not call it Roundtine?)
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To: ConservativeMind

Bkmk


11 posted on 02/03/2026 6:25:32 PM PST by sauropod
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To: Wilderness Conservative

12 posted on 02/03/2026 8:25:17 PM PST by dfwgator ("I am Charlie Kirk!")
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