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Pfizer scraps daily weight loss pill after liver injury in one patient
CNBC ^ | April 14, 2025 | Annika Kim Constantino

Posted on 04/14/2025 7:00:39 AM PDT by Red Badger

Key Points

Pfizer said it would end development of its experimental daily weight loss pill after a patient experienced a liver injury that was potentially caused by the drug in a trial.

The patient’s liver enzymes “recovered rapidly” after they stopped taking the pill, which is an oral GLP-1 drug called danuglipron.

The patient had elevated liver enzymes, which often indicate damage to cells in the liver, but did not experience any liver-related symptoms or side effects, a Pfizer spokesperson told CNBC.

The announcement adds to a string of setbacks in the company’s bid to win a slice of the booming market for GLP-1s, which mimic gut hormones to tamp down appetite and regulate blood sugar.

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(Excerpt) Read more at cnbc.com ...


TOPICS: Business/Economy; Education; Food; Health/Medicine
KEYWORDS: pfizer
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To: dljordan

They were given immunity in Federal lawsuits, but apparently individual STATES’ AGs are stepping up to sue the bastards!.........


21 posted on 04/14/2025 8:05:31 AM PDT by Red Badger (Homeless veterans camp in the streets while illegals are put up in 5 Star hotels....................)
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To: Red Badger

OK you win the thread!


22 posted on 04/14/2025 8:44:06 AM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: Red Badger
The patient had elevated liver enzymes

Statin drugs are known to do the same thing. Why haven't they been scrapped?

23 posted on 04/14/2025 8:59:49 AM PDT by Fresh Wind (Kamala defines herself in just 4 words..."Nothing comes to mind.")
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To: Fresh Wind

They are killing people slowly..........Just the way BG likes it.........................


24 posted on 04/14/2025 9:04:53 AM PDT by Red Badger (Homeless veterans camp in the streets while illegals are put up in 5 Star hotels....................)
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To: Red Badger

Most statins are available as generics, so Big Pharma is working hard to create new drugs that restore their profit margin.


25 posted on 04/14/2025 9:12:34 AM PDT by Fresh Wind (Kamala defines herself in just 4 words..."Nothing comes to mind.")
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To: Red Badger

Asinine response. This one patient might be an outlier . Check to see if there was something odd about his liver and if the others do not have that problem resume the testing.

Livers are not livers. 20% of citizens have a fatty liver. Their livers react differently than the others.


26 posted on 04/14/2025 9:36:31 AM PDT by bobbo666
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To: Fresh Wind

Money.


27 posted on 04/14/2025 9:39:57 AM PDT by Polynikes (Nicht geimpft Mensch 2nd Klasse)
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To: bobbo666

Probably stopped by their legal department.............


28 posted on 04/14/2025 9:40:58 AM PDT by Red Badger (Homeless veterans camp in the streets while illegals are put up in 5 Star hotels....................)
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To: alloysteel
Weight loss? Aren’t GLP-1 drug variations supposed to be for control of HbA1c blood levels, related to Type 2 diabetes?

Yes, GLP-1s do a remarkable job controlling A1C levels in Type 2 patients. It's possible for a drug to treat multiple indications however, and weight loss is another indication that has received FDA approval for some of the GLP-1 medicines.

29 posted on 04/14/2025 11:46:20 AM PDT by Lou L (Health "insurance" is NOT the same as health "care")
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To: grey_whiskers; metmom; ransomnote
Great vid, with recording of convo, at link...

🚨Cover-up caught on camera! ER staff at @bswhealth call security on @Berkeley4peace after admitting shots cause heart damage. pic.twitter.com/7nuol2OtW7— Mary Talley Bowden MD (@MdBreathe) April 15, 2025


30 posted on 04/15/2025 5:46:27 PM PDT by Jane Long (Jesus is Lord!)
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