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Scientists discover 'master switch' in the human body that reverses cell ageing
Daily Mail ^ | 02/25/2025 | William Hunter

Posted on 02/25/2025 9:18:12 PM PST by SeekAndFind

A cure for ageing sounds like something right out of a wild science-fiction film like The Substance.

But scientists could now be close to making this a reality.

Researchers from Osaka University, Japan claim to have found a cellular 'master switch' which can reverse the process of ageing.

This protein, called AP2A1, could be the key to future treatments that will turn back the body's biological clock and undo the damage caused by old age.

As our bodies get older, we build up a growing number of old or 'senescent' cells which stop dividing and functioning as they should.

These 'zombie cells' don't die but rather continue to grow and pump out inflammatory chemicals which contribute to age-related diseases.

However, the researchers found that they could turn senescent cells back into young, healthy cells simply by reducing the amount of the protein AP2A1.

In theory, that means scientists could remove the cause of age-related diseases like Alzheimer's or arthritis by reversing the process of senescence at the cellular level.

The body's ageing process is incredibly complex and there is no single factor responsible for why we get old.

However, cell senescence is one process which appears to play a significant role in bringing on the negative consequences of getting older.

Professor Richard Faragher, an expert on cell ageing from the University of Brighton who was not involved in the study, says: 'Normal cells monitor the number of times they have been called on to divide as a cancer prevention mechanism.

'So, after a variable number of divisions, these cells become senescent which means they activate pathways to ensure they will not divide again.'

Senescent cells also 'radically change the way in which they behave' and start to produce inflammatory molecules and enzymes which degrade the surrounding tissue.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: ageing; aging; alzheimers; ap2a1; arthritis; cells; fakenews
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To: Bob434

I figure that AI will help, where it is focused upon detecting patterns that we would otherwise miss.

I prefer that our minds struggle with observations and study, so that we do not lose self-discipline and learning.

After struggle, turn on AI, and see if it sees:

- some complex pattern that leads to an understanding of - for example: some cancer mechanism.

- some pattern of mechanical issues that indicate a technical situation in need of attention, SOONER than expected / planned.

And, before all that, I prefer that we ask God for help. (And I wish that I was a lot better at choosing to do that . . . but I am a little better at remembering . . . once I am involved. Sigh.)


21 posted on 02/25/2025 11:11:55 PM PST by linMcHlp
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To: SeekAndFind

Hillary will live forever.


22 posted on 02/25/2025 11:43:47 PM PST by Revel
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To: Revel

Bryan Johnson is one major step forward for him. His motto is don’t die.


23 posted on 02/26/2025 12:25:28 AM PST by magua (It's not racism, it's just that thisBecause it’s being reported that a lot of this started in 2015.)
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To: Fai Mao

>> ~Revelation 9:6

Word!


24 posted on 02/26/2025 12:51:11 AM PST by Nervous Tick (Hope, as a righteous product of properly aligned Faith, IS in fact a strategy.)
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So collecting social security at age 300 is now a chance?...where do I sign up.


25 posted on 02/26/2025 1:14:35 AM PST by pricilla (one should always try to be smarter than the equipment one is operating - Amajato)
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To: Strict9
finally. How do I turn on my switch?

You'd better also learn how to turn it back off, too!

A Short Drink from a Certain Fountain

Regards,

26 posted on 02/26/2025 1:26:30 AM PST by alexander_busek (Extraordinary claims require extraordinary evidence.)
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To: lee martell

There are no doubt limits on how much aging can be delayed or reversed. The accumulation of damaged proteins known as advanced glycation end products is probably one.


27 posted on 02/26/2025 2:38:49 AM PST by Rockingham
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To: SeekAndFind

Calling Dr. Fauci...Dr. Fauci, Dr. Fauci...Calling Dr. Fauci...


28 posted on 02/26/2025 3:18:49 AM PST by equaviator (If 60 is the new 40 then 35 must be the new 15.)
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To: SeekAndFind

Bookmark


29 posted on 02/26/2025 3:35:06 AM PST by aquila48 (Do not let them make you "care" ! Guilting you i9s how they. control you. )
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To: SeekAndFind

“They” are not going to let 7 billion “useless eaters” rejuvenate and live long lives. This switch process will be reserved for the elite of the breakaway civilization, who view themselves gods already.


30 posted on 02/26/2025 3:39:09 AM PST by Sirius Lee ("Never argue with a fool, onlookers may not be able to tell the difference.”)
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To: SeekAndFind

I’ll stick with mortality.


31 posted on 02/26/2025 3:46:48 AM PST by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: SeekAndFind

Boosterspice. Yet another Larry Niven prediction.


32 posted on 02/26/2025 3:53:29 AM PST by The Free Engineer
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To: Strict9

Will we be young and dumb again or can we take our hard earned wisdom back with us?


33 posted on 02/26/2025 4:02:28 AM PST by oldasrocks
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To: Lazamataz

Cells have a finite number of divisions.

This would just let you age better, not be immortal


34 posted on 02/26/2025 4:09:59 AM PST by TheThirdRuffian (Orange is the new brown)
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To: SeekAndFind

bkmk


35 posted on 02/26/2025 4:12:22 AM PST by xenia (In a Time of Universal Deceit — Telling the Truth Is a Revolutionary Act - George Orwell)
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To: Angelino97

As somebody or other once said, ‘It isn’t death we fear, but the stroke of death.’


36 posted on 02/26/2025 4:13:56 AM PST by ArtDodger
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To: SeekAndFind

Give the meds to biden, then turn biden over to the Justice Department.


37 posted on 02/26/2025 4:37:52 AM PST by daku
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To: Lazamataz
I don’t know that this is a good thing. Picture an immortal George Soros.

Or Trump. Or Rush.

38 posted on 02/26/2025 4:38:50 AM PST by TangoLimaSierra (⭐⭐To the Left, The Truth is Right Wing Violence⭐⭐)
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To: Fred Nerks

Reverse aging PING !


39 posted on 02/26/2025 4:54:09 AM PST by Candor7 (Ask not for whom the Trump Trolls,He trolls for thee!),<img src="" width=500</img><a href="">tag</a>)
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To: SeekAndFind

Oh Lord, George Soros will be around forever.


40 posted on 02/26/2025 5:15:50 AM PST by dljordan
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