Posted on 09/14/2024 1:54:53 PM PDT by ConservativeMind
Insulin resistance is associated with 31 different diseases, and in women, is also linked to higher odds of early death. This is according to a study of data on hundreds of thousands of people.
There is compelling evidence of links between insulin resistance and conditions as diverse as Parkinson's disease, gout and sciatica.
Insulin resistance is also a risk factor for cardiovascular disease.
To find out more, Ms. Jing Wu and colleagues analyzed data from the UK Biobank.
The study involved 429,159 participants. Levels of blood sugar and fats, including cholesterol, were used to calculate each participant's TyG index—a measure of insulin resistance.
Participants with a higher TyG score, and so a higher degree of insulin resistance at the start of the study tended to be men.
By tracking the participants' health for a median of 13 years, the researchers were able to link insulin resistance with 31 diseases.
Specifically, every one-unit increase in insulin resistance was associated with an 18% higher risk of sleep disorders, an 8% higher risk of bacterial infections and a 31% higher risk of pancreatitis.
The relationship between insulin resistance and diabetes (+166% or 2.66 times higher risk), gout and dyslipidemia (unhealthy levels of blood fats, +61%) and related disorders was particularly strong.
Other associations, such as those between insulin resistance and gout, Parkinson's disease and sciatica, were new to science.
"We found that every one-unit increase in insulin resistance increased the risk of gout by 65% but decreased the risk of Parkinson's disease by 16%," says Ms. Wu. "Additionally, every one-unit increase in insulin resistance was linked to a 10% higher likelihood of sciatica."
In females, every one-unit increase in insulin resistance was associated with an 11% higher risk of dying during the study period.
(Excerpt) Read more at medicalxpress.com ...
There comes a point where your body won’t shove excess carbs into fat cells much anymore—even new cells aren’t being properly made to hold it. Insulin first helps organs and muscles with energy, then if too much remains, the rest is supposed to be shuttled into fat cells. If fat cells are refusing it, the blood keeps this corroding blood glucose just hanging around to cause inflammation just about everywhere, it seems. We see it in higher than healthy levels on a glucose meter. If like a relative, you can have a blood sugar reading of 400+ hours after a meal and 220 still the next morning, yet, be hungry for more sweets.
Yeah, other diseases do follow, sadly.
The body can only take a certain level of abuse before it blows up another endemic issue, caused by insulin resistance from truly bad eating and exercise habits.
Bkmk
Get that A1c down below 6 if possible. Sustained high glucose levels are organ killers and corrode the blood increasing the chances of a stroke.
“Insulin resistance is linked to over 30 diseases—and to early death in women, finds UK study”
Insulin Resistance will generally lead to early death in Men and Woman (and other concepts). Personally, I’m convinced that the best way to prevent Insulin Resistance (and thus Type 2 Diabetes) is to fast (water, black coffee, salt, only) for 120 hours continuous, once a year or so. Otherwise, I’d be an insulin junkie, based on the horrific ‘food’ that I ate. But others, feel free to roll the dice.
The natural health community has been on that for years.
They are way ahead of the federal government on health progress.
TyG index explained
The triglyceride and glucose index is a screening method for insulin resistance that is very simple to use and only requires two laboratory determinations: serum triglycerides and serum glucose. According to a study by Salazar et al. insulin resistance cut off is placed at the TyG index value of 4.49, with a sensitivity of 82.6% and specificity of 82.1% (AUC=0.889, 95% CI: 0.854-0.924)
Subjects with an index of 4.49 or greater are likely to suffer from insulin resistance.
The TyG equation is:
TyG = ln [Fasting triglyceride (mg / dl) x Fasting glucose (mg / dl)] / 2
Ultrasound is the first-line tool to detect liver steatosis but it may not be fully available or may require extra costs. It also has the limitation of detecting steatosis if present in more than 20-30% of hepatocytes. Therefore, prediction tools that are less costly and non-invasive are being sought. The TyG is considered a screening tool for large-scale studies. The reason is its accuracy and easiness to be calculated with data obtained from medical records.
That doesn't look good.
Thanks for letting us know about this index, ConservativeMind.
UK studies should look into deaths due to “proximity to muslim disease”.
Are they sure that they have not misspelled “Resistance to islam Disease”?
We know that the pharma industry makes little money if their drugs provide a cure AS COMPARED to managing an illness for the patient's lifetime.
Many of us have watched info-commercials on the Web promoting so-called solutions for T2 diabetes, which claim to either cure the disease and/or provide better control than the drugs your doctor prescribes.
I am skeptical of both the pharma industry, and the pseudo-science "diabetes cure supplements" industry.
Nevertheless, are there any T2 diabetics out there that have been 'cured' of T2 diabetes, i.e., insulin resistance - using supplements? If so, would you share which supplements worked for you? Thanks!
Health Updates - bump for later....
Pre disposed here... I totally changed my intake, and I ate healthy. Nowadays I eat between 1pm and 7pm, no snacks, no simple carbs, complex carbs are now heavily monitered, greens are good, protein is on the menu. Water, tea and coffee. Exercise and stretch.
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