Posted on 08/05/2024 12:17:41 PM PDT by fastrock
The smartest people I know are Freepers. Hopefully, y’all can give me some advice
My 72yo wife has ulcerative colitis (UC), she’s in her 6th month of trying to get it into remission. UC is bleeding ulcers in your colon – therefore rectal bleeding and diarrhea, poor girl has it hugely. Her last UC episode, which went into remission within a couple months, was 17 year ago when she was 55yo. She’s taken all her biologic initial dosages of Remicade. We have Medicare and Medigap insurance, we live in KY in a major metro area.
Her blood test results are Hemoglobin is 7.7, – normal is 15. If hemoglobin drops to 7.0 they give her blood transfusions. Iron count is 10 – normal is 30.
We and our 38yo son have not taken the Wuhan vaccines. If my wife needs a blood transfusion, can they use my or our son’s blood for the transfusion? I’m concerned about spiked proteins in the blood supply from random donors.
Or actually, my question is “how do I go about getting the Gastro Dr to use either my blood or our son’s blood vs general population blood?
Gag on a gnat and swallow a camel
Transplanting old organs promotes senescence in young recipients
Abstract
In clinical organ transplantation, donor and recipient ages may differ substantially. Old donor organs accumulate senescent cells that have the capacity to induce senescence in naïve cells. We hypothesized that the engraftment of old organs may induce senescence in younger recipients, promoting age-related pathologies. When performing isogeneic cardiac transplants between age-mismatched C57BL/6 old donor (18 months) mice and young and middle-aged C57BL/6 (3- or 12- month-old) recipients , we observed augmented frequencies of senescent cells in draining lymph nodes, adipose tissue, livers, and hindlimb muscles 30 days after transplantation. These observations went along with compromised physical performance and impaired spatial learning and memory abilities. Systemic levels of the senescence-associated secretory phenotype factors, including mitochondrial DNA (mt-DNA), were elevated in recipients. Of mechanistic relevance, injections of mt-DNA phenocopied effects of age-mismatched organ transplantation on accelerating aging. Single treatment of old donor animals with senolytics prior to transplantation attenuated mt-DNA release and improved physical capacities in young recipients. Collectively, we show that transplanting older organs induces senescence in transplant recipients, resulting in compromised physical and cognitive capacities. Depleting senescent cells with senolytics, in turn, represents a promising approach to improve outcomes of older organs.
https://www.amjtransplant.org/article/S1600-6135(23)00803-1/fulltext
Happens to a friend’s child in her 30s. You would think they would try to match
Therefore we want young Organs and bloood!
Young people can be donors for old people but old people should never be donors to young people. It is simple health hygiene when you think about it.
Agree.
We have a family member who’s suffered for years ... and, refuses to see a Naturopath.
Sad to watch. She’s essentially a prisoner in her own home.
I think that you’ll appreciate the angle of my book rewrite...
...if I ever find the motivation to do so (VERY long story and some of it still held close to the chest).
Family members and friends can donate blood in a procedure called a “directed donation”.
To arrange the patient’s doctor must contact the blood donor services team at least seven business days before the patient’s transfusion. The doctor will need to submit a Red Cross Special Collections Order form so the Red Cross can collect blood from the selected donors.
NOT true, in all areas.
We tried to do this WAY in advance, for a family member (not jabbed) to provide non-jabbed blood.
The hospital system (one of the two large system, in Houston) said, Sorry, no. We can only accept blood from in-house/provided by OUR supplier.
How disgusting is that?
Who knows what kind of things they ended up with in their xfusion.
Prayers up, fastrock, that you/your wife can make safe arrangements, for YOUR blood, for this.
Keep us posted, please, as I’m sure there are many other FReepers who would like to know about this, as well.
I think I certainly would.
Please keep be posted, if you complete your book.
God bless you!
Well, at least the abstract ends on a sort-of positive note.
My question for you: Would you rather undergo the treatment and take your chances, or just die?
I am B neg. But 2000 miles away if that helps.
I would bank my own blood or hire a young, healthy dude to donate blood for me.
How long ago was 1980?
“NOT true, in all areas.”
Not surprised at all it’s area specific. I’ve seen it work with a friend and a coworker’s families. The system is less than perfect, for sure.
Have they perfected ‘banking’ your own organs or bone marrow?
Any we find many new diseases every year that have been around forever and will continue to do so until the end of the Earth. No medical procedure with donor tissues and fluids is without risk, be it 1980 or 2024 or 25789.
Listen to her doctor. And don't shilly-shally.
Since you are up for suggestions, have you considered taking her to a barber?
https://www.youtube.com/watch?v=edIi6hYpUoQ
Wow. I would have guessed that was impossible.
As long as the donor was Hans Delbruck, then it’s ok. He was a scientist and a saint.
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