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First-Of-Its-Kind Study Explains Why Some People Don't Get COVID-19
Epoch Times ^ | 06/20/2024 | Marina Zhang

Posted on 06/20/2024 9:52:04 PM PDT by SeekAndFind

Researchers have discovered why some people remain uninfected by the COVID-19 virus—even after their nasal cavities are exposed to it.

According to a recent study, these people have faster and more subtle immune responses than those who develop symptomatic COVID-19.

“These findings shed new light on the crucial early events that either allow the virus to take hold or rapidly clear it before symptoms develop,” Dr. Marko Nikolić, senior author of the study and honorary consultant in respiratory medicine at the University College London, said in the press release.

The study, published in Nature on Wednesday, was a human challenge study conducted by researchers from the UK and the Netherlands. It is the first of its kind wherein participants were deliberately exposed to SARS-CoV-2, the virus that causes COVID-19.

Researchers recruited 16 young, healthy participants under 30 for the study. None had comorbidities, and none had ever previously been infected with COVID-19 or vaccinated.

Before the study received peer review, a preprint of it was made available online in April 2023.

3 Different Immune Responses

The 16 individuals responded to the virus exposure differently and were grouped accordingly.

The first group contained six symptomatic people. The study authors categorized them as having sustained infections.

People in the second group were asymptomatic but still tested positive for COVID-19 with PCR tests. These participants were categorized as having transient infections.

The third type of people were asymptomatic and continuously received negative COVID-19 PCR test results. The authors confirmed that these participants were infected but cleared their infections so rapidly that the infections were dubbed “abortive.”

The second and third groups, who had asymptomatic COVID-19, had faster or more subtle immune responses, according to the authors.

On Day 1, the authors detected immune cells that migrated to the nose—the site of infection—in the asymptomatic groups.

However, people who tested negative for COVID-19 recruited fewer immune cell types, while the COVID-19-positive group recruited all immune cell types.

Symptomatic people with sustained COVID-19 infections had slower and more systematic immune responses. These participants had all types of immune cells going into the nose on Day 5 rather than Day 1.

Genetic Factors

Individuals with high expression of specific genes, such as HLA-DQA2, “are better at preventing the onset of a sustained viral infection,” the authors wrote.

Other studies have shown that increased activity of HLA-DQA2 in the blood is associated with milder COVID-19 progression.

HLA-DQA2 is one of many human leukocyte antigen (HLA) genes. HLA genes make proteins displayed on the cell surface. When pathogens infect cells, HLA proteins signal to immune cells that they have been infected.

The authors said their data confirm that HLA-DQA2 activity protects against further production of SARS-CoV-2 virus in infected cells.

Symptomatic People Had Systematic Responses

Only people with symptomatic COVID-19 displayed systematic interferon responses. Interferons are messengers of the immune system that help reduce or aggravate immune and inflammatory activities.

The authors were surprised to find that interferons in the blood were activated before those at the infection site. Interferon activity in the blood peaked on Day 3 of the infection; however, interferon activity at the infection site—the nose—was not detected until Day 5.

In the press release, the authors said that slow immune responses in the nose could have allowed the infection to establish itself quickly.

Asymptomatic people did not have systemic interferon reactions and rarely had infected cells.

Unsurprisingly, “infected cells were almost exclusively found” in the nasal cavities of symptomatic people, the authors wrote. The cells lining participants’ nasal cavities start producing SARS-CoV-2 virus, contributing to increased viral load.

“We now have a much greater understanding of the full range of immune responses, which could provide a basis for developing potential treatments and vaccines that mimic these natural protective responses,” said Dr. Nikolić.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid; covid19; covidtruth; genealogy; godsgravesglyphs; helixmakemineadouble; hladqa2; immunity; yersiniapestis
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1 posted on 06/20/2024 9:52:04 PM PDT by SeekAndFind
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To: SeekAndFind

If you don’t get COVID, please send China a sample of your DNA so they can update their virus. You can reach them through the DNC.


2 posted on 06/20/2024 9:56:36 PM PDT by Telepathic Intruder
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To: SeekAndFind

The people who don’t get that imaginary sickness are ones who eschew attention-seeking behavior.


3 posted on 06/20/2024 10:15:41 PM PDT by HIDEK6 (God bless Donald Trump)
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To: SeekAndFind
I'm type 2 diabetic, on meds for it, on high bp meds, thyroid as well....I am over weight...

lots of comorbidities...

no vax...no covid...and I worked several months on a covid floor in the hospital, not directly,but on the same floor...

none of us here in this hospital have had it, and we've been tested.....

meanwhile, people who got vaxxed up the ying yang get repeatedly sick with supposed covid....

I owe it to our vitamin intake.

4 posted on 06/20/2024 10:15:59 PM PDT by cherry
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To: SeekAndFind

That’s fake news, in my opinion.

SOme people already had immunity to whatever corona virus they were exposed to. You don’t have to have the exact virus circulating - you just have to be exposed to similar types of viruses.

That’s why they bothered to put out this cya story. THey couldn’t lock us down and push through EUA’s if they hadn’t claimed that NONE OF US HAD IMMUNITY, and they did that by claiming that ‘Covid’ was categorized as a ‘novel virus’. It was never a novel virus. The CDC/Fauci lied.

The PCR They used throughout the Plandemic was not a valid test for ‘Covid’. That PCR was configured to identify a ‘related corona virus’ because the CDC said it did not have an isolated sample of Covid to use.

SO the CDC/Faucist/NIH/FDA liars all knew that people testing positive without symptoms were not sick, as the PCR wouldn’t identify illness (based on the inventor of the PCR).

It’s all smoke and mirrors, they are trying to explain away their lies.


5 posted on 06/20/2024 10:34:54 PM PDT by ransomnote (IN GOD WE TRUST)
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To: SeekAndFind

My friend lived through the Spanish Flu and died at 101 and 5 months

Never had a cold or flu

Lots of people never get sick


6 posted on 06/20/2024 10:48:28 PM PDT by Vendome (I've Gotta Be Me https://youtu.be/wH-pk2vZG2M)
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To: SeekAndFind

Vitamin D levels?


7 posted on 06/20/2024 10:48:57 PM PDT by nickcarraway
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To: ransomnote

“and they did that by claiming that ‘Covid’ was categorized as a ‘novel virus’. It was never a novel virus.”

You mean “Covid,The Virus That Never Existed”?

Isn’t that the Deep Kook party line from the wizards over at The Daily Expose?

I guess they still believe that there is no such thing as the Covid virus, and never was. That’s what they once claimed to believe.

Or did they decide that was just too insane of a idea to keep pushing?

Kind of like the Lizard People thing that their pal David Icke believes.

I dunno. It’s hard keep up on what exactly the “Plandemic” and “poison jab” crowd believe. They now seem shy about stating it as clearly as they did in that one excellent paper they issued. You remember the one, you posted it. Maybe you can ask them and let us know.


8 posted on 06/20/2024 11:41:07 PM PDT by Pelham (President Eisenhower. Operation Wetback 1953-54)
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To: SeekAndFind

University College London is an original guilty party in the Covid mass murder crime.
Join HerrDoktorFauciMengeleGates, NIH, FDA, Pfizer/Moderna/et al. on the gallows


9 posted on 06/21/2024 12:19:59 AM PDT by A strike (no tyranny that cannot be justified by 'climate change')
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To: nickcarraway

Yes. To me, it’s the most important for this type of thing.


10 posted on 06/21/2024 1:04:14 AM PDT by Gaffer
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To: SeekAndFind

Wonder how they would perform against other viruses?

I did not get wuhan flu but I can catch a head cold in a danged minute.

No, I never tested...why would I do that? I don’t want my name associated with that crap in any way...not even to order a “free” kit.


11 posted on 06/21/2024 2:29:38 AM PDT by Adder (End fascism...defeat all Democrats.)
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To: SeekAndFind

Wife and I never got the jab, never got tested and have no idea if we may or may not have had it.

Neighbors which thankfully we can’t even see are all multi-jabbed and have tested positive numerous times, supposedly had covid numerous times and we’re pretty sick.


12 posted on 06/21/2024 4:13:09 AM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: SeekAndFind

Don’t take one of the b.s. “tests”, and you won’t have “covid”, you’ll just have a cold/flu.


13 posted on 06/21/2024 4:31:37 AM PDT by Sicon ("All animals are equal, but some animals are more equal than others." - G. Orwell>)
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To: SeekAndFind

I never took the clot shot and have never had Covid. I just decided not to participate in the Fauci drama.

My blood is in demand atthe blood bank.


14 posted on 06/21/2024 4:45:29 AM PDT by IAGeezer912 (One out of every 20 people on the face of the earth are Americans. We have won life's lottery.)
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To: SeekAndFind

Thought it was unethical to expose people to this most deadly virus. And that’s why we couldn’t determine if masks work.


15 posted on 06/21/2024 5:42:50 AM PDT by Tymesup
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To: Vendome
My friend lived through the Spanish Flu and died at 101 and 5 months

My great-grandmother lived through the Spanish Flu and died at 108. Her husband, my great-grandfather, died from that flu leaving her to raise 5 children.

I know people who were hospitalized with Covid and who almost died. Others like my wife and I contracted the disease but only had mild symptoms.

Freepers who deny the potential dangers of COVID are wrong. The fact is that like many infectious diseases, COVID affects different people differently. My great-grandmother who cared for my great-father until his death was immune to the Spanish flu - my great-father was susceptible and succumbed to the disease. This seeming contradiction can be said of many infectious diseased. One size does not fit all.

16 posted on 06/21/2024 5:47:32 AM PDT by JesusIsLord
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To: nickcarraway
My husband and adult son were super exposed to the virus, but they work outside and kept working during the pandemic...never got anything.
The rest of us have been taking supplements, including lots of D3 since well before covid.
Anecdotal, but still evidence.
17 posted on 06/21/2024 5:55:03 AM PDT by Mrs.Z ("Do not put your trust in princes, in human beings, who cannot save." Ps 146:3)
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To: Telepathic Intruder

It was a bad cold the CDC killed people with once they got them in the hospital.


18 posted on 06/21/2024 6:05:05 AM PDT by bray (It's not racist to be racist against races you do not like.)
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To: SeekAndFind

I had a Covid infecton once, and never had any symptoms.


19 posted on 06/21/2024 6:39:57 AM PDT by Wuli
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To: bray

When I saw the reports coming out of China about bodies piling up in hospitals, it smelled like pure propaganda to me. It was from the point of view of ordinary citizens, which the Chinese government would never allow unless they were controlling it. And the MSM slapped them all over the news right away, not questioning their validity. It was all a covert operation; the CCP and the DNC are colluding to overthrow America’s system of democracy, one step at a time. Meanwhile the DNC claims the Republicans are a threat to democracy, while rigging elections and throwing their political rivals in jail on false charges.


20 posted on 06/21/2024 7:08:50 AM PDT by Telepathic Intruder
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