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New study reveals Viagra improves brain blood flow and could help prevent dementia
Medical Xpress / University of Oxford / Circulation Research ^ | June 7, 2024 | Alastair J.S. Webb et al

Posted on 06/11/2024 2:42:13 PM PDT by ConservativeMind

A new trial reveals that sildenafil, commonly known as Viagra, enhances blood flow to the brain and improves the function of brain blood vessels in patients at a heightened risk of vascular dementia.

This study marks a potentially pivotal step in the fight against this debilitating condition.

Dr. Alastair Webb said, "This is the first trial to show that sildenafil gets into the blood vessels in the brain in people with this condition, improving blood flow and how responsive these blood vessels are.

The significance of this research lies in its potential to transform the treatment and prevention of vascular dementia, which currently lacks specific therapies.

Chronic damage to the small blood vessels in the brain is not only the leading cause of vascular dementia but also contributes to 30% of strokes and 80% of brain bleeds. High blood pressure, reduced blood flow to the brain, and impaired blood vessel function exacerbate these conditions, making the findings of this trial particularly crucial.

The OxHARP trial was a meticulously designed double-blind, placebo-controlled study involving 75 participants who had experienced a minor stroke and showed signs of mild to moderate small vessel disease. Each participant received sildenafil, a placebo, and cilostazol (a similar drug) over three-week periods in a randomized order. The study employed cardiovascular physiology tests, ultrasound, and functional MRI scans to evaluate the drugs' effects.

Key findings include:

- Sildenafil increased blood flow in both large and small brain vessels as measured by ultrasound and MRI scans.

- Sildenafil enhanced the blood flow response to carbon dioxide, indicating improved cerebrovascular function.

- Both sildenafil and cilostazol lowered blood vessel resistance in the brain. Sildenafil caused fewer side effects compared to cilostazol, particularly with less incidence of diarrhea.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: dementia; hh2; highbloodpressure; sildenafil; stroke; viagra
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The same issues that cause a lack of blood flow for men are also present in the brain, it appears.

Consequently, Viagra seems to help both small vessel locations.

1 posted on 06/11/2024 2:42:13 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 06/11/2024 2:42:42 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I need it every day! The Viagra, I mean.


3 posted on 06/11/2024 2:44:10 PM PDT by BipolarBob (I was drowning in self pity until I bathed in the refreshing Lake of Respect.)
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To: ConservativeMind

So ‘thinking with the wrong head’ no longer applies?


4 posted on 06/11/2024 2:45:49 PM PDT by ComputerGuy (Heavily-medicated for your protection)
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To: ConservativeMind

So, they’re saying it’s good for the head?.


5 posted on 06/11/2024 2:46:16 PM PDT by bleach (If I agreed with you, we would both be wrong.)
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To: ConservativeMind

Doesn’t it cause headaches?


6 posted on 06/11/2024 2:47:46 PM PDT by C210N (Mundus vult decipi, ergo decipiatur.)
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To: ConservativeMind

Lucky me — my medicare pays 100% for 18 pills every 3 months

Hope my brain is happy with that.


7 posted on 06/11/2024 2:47:58 PM PDT by George from New England (escaped CT back in 2006)
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To: ConservativeMind

So if Viagra improves brain function it might have an unintended effect on its other use, i.e. “nope, not doing dat!”


8 posted on 06/11/2024 2:50:26 PM PDT by dblshot
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To: C210N

yes, according to my wife


9 posted on 06/11/2024 2:52:16 PM PDT by Gene Eric (Don't be a statist! )
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To: ConservativeMind

I know this first hand as a fact. Its given to premature babies in NICU for the exact same reasons.


10 posted on 06/11/2024 2:53:21 PM PDT by know.your.why (<>)
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To: Gene Eric

Bwahahahaha. So true


11 posted on 06/11/2024 2:54:55 PM PDT by miliantnutcase
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To: ConservativeMind

Improves brain flow for guys who think with their


12 posted on 06/11/2024 2:57:58 PM PDT by NWFree (Somebody has to say it 🤪)
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To: ConservativeMind
The HEADLINE should read.. "It's HAPPENED for MEN.. They've found a WAY to Finally Allow the BIG HEAD to do the thinking for the LITTLE HEAD!"


13 posted on 06/11/2024 3:00:54 PM PDT by VideoDoctor
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To: ConservativeMind

I would assume any of the similar drugs (e.g., Cialis) would do the same. Cialis probably even better, in that it last for much longer.


14 posted on 06/11/2024 3:04:45 PM PDT by MeanWestTexan (Sometimes There Is No Lesser Of Two Evils)
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To: ConservativeMind

I took Viagra once, never again. My blood pressure went so high I thought I was going to have a stroke. It seems all that stuff does is raise your BP through the roof I assume with the idea that the high BP will ——>. Yeah OK it makes you “functional” but you also risk dying. I’m sticking to the old fashioned way to be functional: Don’t think of Hillary, Pelosi, Helen Thomas or any other democrat


15 posted on 06/11/2024 3:05:08 PM PDT by GrandJediMasterYoda (As long as Hillary Clinton remains free, the USA will never have equal justice under the law)
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To: ConservativeMind

So the two heads are no longer mutually exclusive??


16 posted on 06/11/2024 3:05:30 PM PDT by eyeamok
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To: GrandJediMasterYoda

I asked Doctor about the risk of this stuff and they said none.
But I do feel a bit more stressed for the time it’s in my system. Approaching 24 hours.


17 posted on 06/11/2024 3:07:18 PM PDT by George from New England (escaped CT back in 2006)
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To: ConservativeMind

Maybe more sex prevents dementia.


18 posted on 06/11/2024 3:08:17 PM PDT by smokingfrog ( sleep with one eye open (<o> --- )
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To: GrandJediMasterYoda

That’s very unusual. They normally lower blood pressure.

In fact, they were being researched as a blood pressure medicine when the “side” effect what discovered by horny Boston University researchers who then used it as a party drug.


19 posted on 06/11/2024 3:11:01 PM PDT by TheThirdRuffian (Orange is the new brown)
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To: smokingfrog

Ron Jeremy last I read was pretty much gone mentally.

Exception to the rule?


20 posted on 06/11/2024 3:16:16 PM PDT by wally_bert (I cannot be sure for certain, but in my personal opinion I am certain that I am not sure..)
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