Posted on 04/06/2023 8:41:39 PM PDT by ConservativeMind
Researchers found that broccoli contains certain molecules that bind to a receptor within mice and help to protect the lining of the small intestine, thereby inhibiting the development of disease.
Said Gary Perdew. "Our research provides strong evidence that cruciferous vegetables, such as broccoli, cabbage, and Brussels sprouts should be part of a normal healthy diet."
According to Perdew, the wall of the small intestine allows beneficial water and nutrients to pass into the body but prevents food particles and bacteria that could cause harm. Certain cells that line the intestine—including enterocytes, which absorb water and nutrients; goblet cells, which secrete a protective layer of mucus on the intestinal wall; and Paneth cells, which secrete lysosomes that contain digestive enzymes—help to modulate this activity and keep a healthy balance.
Perdew and his colleagues found that molecules in broccoli, called aryl hydrocarbon receptor ligands, bind to aryl hydrocarbon receptor (AHR), which is a type of protein called a transcription factor. This binding, they found, initiates a variety of activities that affect the functions of intestinal cells.
To conduct their study, the researchers fed an experimental group of mice a diet containing 15% broccoli—equivalent to about 3.5 cups per day for humans—and fed a control group of mice a typical lab diet that did not contain broccoli.
The team found that mice that were not fed broccoli lacked AHR activity, which resulted in altered intestinal barrier function, reduced transit time of food in the small intestine, decreased number of goblet cells and protective mucus, decreased Paneth cells and lysosome production, and decreased number of enterocyte cells.
More broadly, added Andrew Patterson, "these data suggest that dietary cues, relayed through the activity of AHR, can reshape the cellular and metabolic repertoire of the gastrointestinal tract."
(Excerpt) Read more at medicalxpress.com ...
Then that’s a definite no
Cabbage juice works wonders for the gut. It’s amazing. Not the most pleasant tasting but very effective for crohns or colitis. I’d say it reduces symptoms up the 75% so it’s not a complete cure for flare ups but it is still worth the time to slow juice them. About a quart a day. I spread it out over 3 different times on an empty stomach.
It probably wouldn’t hurt to add some broccoli. I add some apple to give it a better flavor. Some ginger too. Mint can be added.
I give the pulp to a neighbor for their pigs. It’s like candy to them.
Vile weed.
Good. Get the mice to eat it all.
Tnx
3.5 cups is a bit much.
I just remembered something.
Broccoli “mashed potatoes”
Blend up cooked broccoli, put in some butter, and you do have a treat
Why the heck are they testing the benefits
of eating broccoli on mice?
Last I head, vegans love the stuff.
Test it on them for more viable results.
It’s not like it’s fentenal.
3.5 cups a day would kill a normal mouse!!
Broccoli is over $2.50/lb.
Cheaper to buy a supplement
Sigh....
So that’s how the mice eat it? Cook and a casserole or maybe with some fish how about some spices on it salt and pepper?
Seems like it would be a little bit difficult to get mice to eat cooked broccoli, I’ve never seen anybody bait traps with cooked broccoli before.
Nothing in this study supports or disputes what you’re saying, basically it was I mice that were fed a purified synthesized broccoli Diet. He has no relationship to either cooked or uncooked broccoli it is literally a purified artificial broccoli synthesis that was fed to them with a 15% purity and then mixed with regular mice Chow that was in a controlled group.
Basically the studies conclusion was components of broccoli benefited these cells but nothing in the study can’t be clearly evidenced against a natural diet or normal broccoli preparation.
Nothing in this study supports or disputes what you’re saying, basically it was I mice that were fed a purified synthesized broccoli Diet. He has no relationship to either cooked or uncooked broccoli it is literally a purified artificial broccoli synthesis that was fed to them with a 15% purity and then mixed with regular mice Chow that was in a controlled group.
Basically the studies conclusion was components of broccoli benefited these cells but nothing in the study can’t be clearly evidenced against a natural diet or normal broccoli preparation.
I hate broccoli. I eat it several times a week, but am not happy about it. Have to choke it down to clear it off the plate first so that I can then tuck in and enjoy my supper.
Dila, I don’t understand what you are saying.
From the study:
“Mice were either gavaged with 100 μL of corn oil-containing treatment (VEH, 10 μg/kg ICZ, or 24 μg/kg TCDF) or placed on a 15% w/w broccoli diet, which was adjusted to obtain similar nutritional and caloric content profiles relative to that of defined AIN-93G diet, as previously described and obtained from Dyets Inc.29 The ‘Imperial’ cultivar variety was freeze-dried and ground to a powder before adding it to the diet. The level of glucobrassicin in broccoli was determined as previously described.29 The concentration of glucobrassicin in the ‘Imperial’ cultivar was 9905 nmoles/g dry weight, essentially the same as that observed in the ‘Lieutenant’ cultivar used in a previous study.”
https://li.uscap.org/article/S0023-6837(22)00012-5/fulltext
It is apparent an actual literal form of broccoli was used. It was not heated, or that would have been stated, so it was taken raw and immediately freeze-dried, then ground up for addition to the mouse food.
When steaming, as you added, some key nutrients wind up in the liquid that comes off the broccoli, so ingest that to get its benefit.
Perfect
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