Posted on 02/23/2023 12:25:49 PM PST by nickcarraway
UniSQ academic helps refine knowledge on disease, vitamin interaction by modelling against confounding variables Vitamin D is known to keep our bones and muscles healthy – and now a novel study shows it might also play an important role in protecting us from COVID-19.
In a newly released paper, University of Southern Queensland statistician Dr Zahirul Hoque and colleagues have studied the link between vitamin D levels and COVID-19 infection rates using statistical modelling.
After analysing the health datasets from 10 countries, the team found that individuals with normal levels of vitamin D had significantly lower COVID-19 infection rates than their vitamin D deficient counterparts.
To define this interaction, the team had to discount other variables which could make individuals more susceptible to the disease, such as age, gender and weight.
This study is the first of its kind to investigate the link between vitamin D and COVID-19 while adjusting for confounding variables and country level heterogeneity.
“We started work on this project in 2020, when COVID-19 was at its peak in many countries,” Dr Hoque said.
“Looking at the literature, we found some teams adjusting for different variables, but we did not find any looking at the influence of vitamin D levels on COVID-19 incidence which had also considered other confounding variables.
“It was hard to get data which also included vitamin D levels, but we ended up collecting samples from a good number of countries across many regions in the world.”
Dr Hoque said the team used a negative binomial regression model to counter country-linked heterogeneity and find the association between the independent variables and COVID-19, providing an incidence rate ratio.
The researchers then studied the impact of vitamin D levels on this incidence rate ratio and found that COVID-19 infection was 48 per cent less in people with normal levels of vitamin D (>50nmol/L).
Overall, the team found vitamin D deficiency, aging and the vitamin D deficient, aged community at greatest risk for COVID-19 infection.
“Vitamin D is known to strengthen the immune system and could possibly play a direct role in the prevention of COVID-19,” Dr Hoque said.
“The vitamin has also been shown to exhibit antimicrobial activity against bacteria, fungi and viruses.
“With this research we hope to strengthen our knowledge on COVID-19 and factors which might help to prevent it.”
how did you generate that list of articles based on keyword?
I have a CV-19 Directory with maybe 20 subdirectories that is about 3GB with 3000+ files strictly for CV-19 and are mostly web (URL) links except for those articles that I think might disappear.
Those articles I save as a PDF with the Opera browser.
So I loaded the CV-19 directory, sorted by date modified, (earliest 1st) and searched on "Vitamin D".
Results were either links with "Vitamin D" in the title or in text or pdf files of files on my PC.
I've got a new PC so I'm still loading my normal tools and trying to get rid of M$ Office 365 so I loaded my owned version of FastStone Capture (a great screen capture program) and used the scrolling screen selection and captured the multi-screen search results and saved to a jpg.
Then I installed and loaded my Postimages.Org site, transferred the FastStone jpg got the URL for the full image, copied it and then pasted the img src to my post.
Easy peasy. ;-)
So what you see there are my direct links re Vit. D.
If there's any article title or two or three, FReepmail me and I'll send you the link(s).
TH54
ok thanks.
From what I’ve read about 90 percent of the people who die of covid have vitamin d deficiencies.
I’ve also read that you want to keep your vitamin d in the 50 ng/ml -80 ng/ml range. that can require a lot more vitamin d than people normally take. As well, you need to increase your glutathione levels by taking NAC and glycine—for a number of reasons. one of those reasons is that glutathione aids in the uptake of vitamin d.
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