Posted on 11/04/2022 9:11:37 AM PDT by Red Badger
Bacteria can travel through the olfactory nerve in the nose and into the brain in mice, where it creates markers that are a tell-tale sign of Alzheimer’s disease. Picking can damage the lining of your nose, increasing the number of bacteria that can go up into your brain.
In new research, Griffith University scientists have demonstrated that a bacteria can travel through the olfactory nerve in the nose and into the brain in mice, where it creates markers that are a tell-tale sign of Alzheimer’s disease.
The study revealed that Chlamydia pneumoniae, a type of bacteria that can cause respiratory tract infections, such as pneumonia, exploited the nerve extending between the nasal cavity and the brain as an invasion path to assault the central nervous system. In response, the cells in the brain began depositing amyloid beta protein which is a hallmark of Alzheimer’s disease. The study was published earlier this year in the journal Scientific Reports.
“If you damage the lining of the nose, you can increase how many bacteria can go up into your brain.” — Professor James St John
Professor James St John, Head of the Clem Jones Center for Neurobiology and Stem Cell Research, is a co-author of the world first research.
“We’re the first to show that Chlamydia pneumoniae can go directly up the nose and into the brain where it can set off pathologies that look like Alzheimer’s disease,” Professor St John said. “We saw this happen in a mouse model, and the evidence is potentially scary for humans as well.”
The olfactory nerve in the nose is directly exposed to air and offers a short pathway to the brain, one which bypasses the blood-brain barrier. It’s a route that bacteria and viruses have sniffed out as an easy one into the brain.
Bacterium Chlamydia pneumoniae (green) inside the brain of a mouse, and surrounded with beta amyloid peptide (red) (amyloid peptide is a hallmark problem in Alzheimer’s disease.) Credit: Griffith University
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The team at the Center is already planning the next phase of research and aims to prove the same pathway exists in humans.
“We need to do this study in humans and confirm whether the same pathway operates in the same way. It’s research that has been proposed by many people, but not yet completed. What we do know is that these same bacteria are present in humans, but we haven’t worked out how they get there.”
There are some simple steps to look after the lining of your nose that Professor St John suggests people can take now if they want to lower their risk of potentially developing late-onset Alzheimer’s disease.
“Picking your nose and plucking the hairs from your nose are not a good idea”,” he said.
“We don’t want to damage the inside of our nose and picking and plucking can do that.
“If you damage the lining of the nose, you can increase how many bacteria can go up into your brain.”
Smell tests may also have potential as detectors for Alzheimer’s and dementia says Professor St John, as loss of sense of smell is an early indicator of Alzheimer’s disease. He suggests smell tests from when a person turns 60 years old could be beneficial as an early detector.
“Once you get over 65 years old, your risk factor goes right up, but we’re looking at other causes as well, because it’s not just age—it is environmental exposure as well. And we think that bacteria and viruses are critical.”
Reference: “Chlamydia pneumoniae can infect the central nervous system via the olfactory and trigeminal nerves and contributes to Alzheimer’s disease risk” by Anu Chacko, Ali Delbaz, Heidi Walkden, Souptik Basu, Charles W. Armitage, Tanja Eindorf, Logan K. Trim, Edith Miller, Nicholas P. West, James A. St John, Kenneth W. Beagley and Jenny A. K. Ekberg, 17 February 2022, Scientific Reports. DOI: 10.1038/s41598-022-06749-9
This research was supported by the Goda Foundation and the Menzies Health Institute Queensland.
So Joes not just a sniffer
They better not say “but eating them reduces the threat”
I’m doomed...
Now I understand why I’ve lost sight of things like the Clebsch-Gordan coefficients...😳
You do know, when you pick your nose, you’re not supposed to dig in two or three inches.
If you are in your "second childhood" you are probably picking your nose again.
Chlamydia Pneumoniae
Link: https://www.std-gov.org/blog/chlamydia-pneumoniae/#treatment infection is treated by antibiotics if the patient is severely uncomfortable but in most cases, people recover on their own without taking any medications. This is because their immune systems fight and defeat C. Pneumoniae. There are many types of antibiotics available to treat C. pneumonia and the doctor will prescribe an antibiotic depending on the severity of the condition.
If you’re not on antibiotics (and I suggest them only for last ditch efforts) work on your immune system. I use Vitamin D3, NAC, Glycine, GABA Turmeric and Grape Seed extract. Also flush niacin and every other day, Zinc Quercetin.
That’s nice. Wouldn’t it be better if the study could actually answer its own question though? Between Alzheimer’s and nose picking, which is cause and which is effect?
Answer: Neither one is a cause. Both Alzheimer’s and nose picking can be caused by prion disease.
https://www.ucsf.edu/news/2019/05/414326/alzheimers-disease-double-prion-disorder-study-shows
So how did the researcher get the mice to pick their noses?
Coke......................
I was a finalist in a regional Digging for Boogers contest. It was a short lived TV show modeled after Dialing for Dollars.
Coca Cola? That is what naïve, straight-laced little me thought they were talking about when I first heard about “coke.” :)
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