Posted on 07/29/2022 1:34:12 PM PDT by ConservativeMind
Hormone therapy for prostate cancer increases the risk of cardiovascular disease-related death especially in older men, according to a population study involving more than 13,000 patients.
The highest risk was for coronary heart disease and stroke. The increased risks were apparent from the second year after cancer diagnosis and were more pronounced in older men.
"Hormone therapy is often used for patients with prostate cancer," says lead author Justinas Jonusas. "Our results suggest clinicians should consider risk reduction and mitigation strategies for cardiovascular disease when developing a treatment plan for men diagnosed with prostate cancer, particularly for older patients."
The researchers found:
- a more than two-fold increase in the risk of death from cardiovascular disease in men who had received hormone therapy.
- a higher risk of cardiovascular disease-related death from the second year onwards following a prostate cancer diagnosis.
- an almost five-fold higher risk in the 70 to 79 age group of those who received hormone therapy compared to those who did not.
The team also assessed the risk of death from several subtypes of cardiovascular disease, identifying there was a higher risk of dying specifically from stroke or coronary heart disease. These risks were 42% and 70% higher, respectively, in men treated with hormone therapy compared to those who were not.
"Prostate cancer is typically diagnosed in older men, over 65 years or older—and many of them will have already been diagnosed with cardiovascular disease," says Jonusas. "It is therefore concerning that we found such a tremendous increase in the risk of cardiovascular disease-related death in elderly males receiving hormone-lowering drugs. Consequently, we would like to express our notion that this group of patients should be screened for pre-existing cardiovascular disease and their risk factors to minimize the risk of dying from these conditions."
(Excerpt) Read more at medicalxpress.com ...
Great, pet the puppy, slap the puppy...
Does anyone here know anyone who died of prostate cancer? I mean, knew their ins and outs of their journey?
"It's like my father always said: 'Rosanne Rosannadanna, it's always
Somethin'. Either you die of prostrate cancer, or else you die of a
heart attack. Either way, you're gonna DIE.'"
The drug used to fight prostate cancer is lupron, the same drug given to prepubescent children by adults who want to “trans” them. It is abuse of the highest order. Lupron suppresses the production of testosterone almost to a level of undetectability. Needless to say, this has deleterious effects on numerous body systems and functions.
“I know we take hormone therapy when normal approaches aren’t assured of completely get rid of prostate cancer, but getting early cardio help, and taking better care of ourselves, could be of large benefit.”
I am on hormone therapy for metastatic prostate cancer.
There are two imperatives:
1. No less than 150mins of pure, moderate cardio per week.
2. No less than 2, 30min weight lifting sessions per week.
If you don’t do that, you will turn into a girl and likely die from a heart attack.
I am on the journey, 5 years 4 months 12 days in ...but who is counting? I have had bad times, but all in all, I am surprised how active, healthy and fit I still am. I have been on the hormone stoppers, for 4 years or so, took 1 year off and the worse thing that happened was I felt even better. Doing good, one day at a time and be happy and positive in your personal life. People notice and appreciate it.
It is a crime against humanity, what they are doing with scalpels, drugs and through mental health abuse(counseling). They deserve the same fate as that given at Nuremburg.
I sheet the bed on the weight lifting, but a brisk 3-4 miles walking, and 5 miles on my bike, keeps me happy. I keep putting off joining a gym, just lazy I guess. I have a membership waiting for me, paid for by my daughters, I just haven’t cashed in on their promise to pay.
As I see it, you throw everything, plus the kitchen sink, at cancer, especially at the metastatic stage.
I would rather know with pretty good certainty that cancer won’t come back, even if that means extra exercise and other precautions against the side effects of cancer therapy.
It would be nice if so much diligence did not have to be performed.
I personally know three men who have died from prostate cancer.
You can lose ALL your muscle on ADT.
I saw a man at the VA clinic that had arms like an old woman, nothing but flab. He was so weak he could barely walk across the room and used a cane.
He proudly pronounced he was 90 days of zero PSA after 3 years on hormone therapy.
He was 70.
Don’t be that guy.
My father was diagnosed with prostate cancer when he was in his 70’s. He was put on a drug to suppress his testosterone. I assume that is hormone therapy. He died of heart failure just before his 95th birthday.
My father had a prostatectomy at age 56. This was long ago before the PSA test was available. Five years later during a checkup his urologist ordered a then new PSA and it was 130 (normal is 0-4). One month later it was 160. No imaging studies could locate the metastases. At that time Lupron was a new drug that was not covered by his insurance and would have cost him $600/month. The urologist suggested an alternative - castration. You want to remove the testosterone, right? He told the surgeon “Doc, I’m 61 years old. I’ve got 7 kids and a fat wife. I don’t need them anymore.” That’s my dad. His 3 month post-orchiectomy PSA was 0.00 and it stayed that way until he was 82 living in a nursing home due to Alzheimer’s when the cancer returned and eventually killed him. He never had any heart disease. He had a pretty good run.
My husband’s first doctor wanted him doing hormone therapy. He got a 2nd and 3rd opinion and opted for surgery.
We did so much research on the side effects of hormone therapy. I think that’s why I’m so against at the hormone therapy for kids who want to transition.
I hear you and believe what you say is true. My saving grace is that I am very active, with 15 grandchildren that I play with, roughhouse, swim and ride bikes with. Plus my dog who I have worn out in the 5 years, he is not able to keep up with me as he is 12 and arthritic. I have been noticing that my arms are getting flabby, I have lost my years of lifting and need to work to get it back. I used to have a Total Gym, and worked it 4 days a week for 1 hour. Now the MIL is occupying my exercise room, so I need to join a Gym....ugh... Like I wrote, my daughters will pay when I join.... gotta take them up on it...plus the gym membership has a swimming pool.... Thanks for being assertive, people need to know what is going on. Most Drs do no care enough.
GnRH analogues like Lupron are not only used to treat advanced prostate cancer, but transgenders. Guess they will have an even greater risk of cardiovascular disease due to longer exposure to these drugs.
Quite frankly I’d rather die from a heart attack then cancer.
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