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Shorter life expectancy for people with fatty liver disease (2.8 years less life, if not addressing it)
Medical Xpress / Karolinska Institutet / Hepatology ^ | May 2, 2022 | Ying Shang et al

Posted on 05/02/2022 11:44:50 AM PDT by ConservativeMind

A research group shows that people with fatty liver disease are expected to live almost three years shorter than the general population.

People who have been diagnosed with so-called fatty liver, run an increased risk of developing cardiovascular disease and loss in life expectancy, compared to the general population. These patients have approximately a 2.8 years shorter expected survival, based on collected data from a large number of Swedish patients. However, the risk of death after a heart attack or stroke is still comparable to people without fatty liver.

The results of the study are important because they can be used to facilitate the communication between health care workers and patients with fatty liver.

"It will be easier to communicate around the expected survival of the patient and around the importance of the best possible treatment, which hopefully also can improve the patient's prognosis. In addition, the results indicate that you won't need to examine the liver to see if patients with heart attack or stroke are affected by fatty liver," says postdoc Ying Shang at the Department of Medicine, Huddinge, Karolinska Institutet, the study's first author.

In this nationwide population-based cohort, a collection of extensive data links between national registries where made. Investigating a very large group of patients with fatty liver (> 10,000), the researchers were able to identify all patients with fatty liver in Sweden and compare these with the general population.

"In my research group, there are several ongoing projects, where we investigate better ways to identify which patients with fatty liver are at highest risk for developing serious complications such as cardiovascular disease, death, cirrhosis and cancer," says Hannes Hagström at the Department of Medicine, Huddinge, one of the study's authors.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: disease; fattyliver; liver
I can say we got validation last week that a relative’s fatty liver, diagnosed with an ultrasound, was reversed without the normal weight loss. The changes were going lower carb (not necessarily keto, but under 80 grams of usable carbs a day) and one supplement, Pantethine, following a study from two decades ago. The person was on Pantethine for just under five months. Additionally, no scarring was found.

I will put the study in the next post.

1 posted on 05/02/2022 11:44:50 AM PDT by ConservativeMind
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To: ConservativeMind
The effects of pantethine on fatty liver and fat distribution (56% study participants eliminated fatty liver in six months)

https://freerepublic.com/focus/f-chat/4008349/posts

2 posted on 05/02/2022 11:45:55 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Now keeping a new list (“Common/Top Issues”) for conditions expected to only concern at least 1% of the population. Ask to be on either the “Common/Top Issues” or “Everything” list.

Please email or private message me if you want on or off of a list and of which list you desire.

3 posted on 05/02/2022 11:46:36 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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Can I get the extra 2.8 years in my 20s instead of my 80s?


4 posted on 05/02/2022 11:48:01 AM PDT by dsrtsage ( Complexity is just simple lacking imagination)
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To: ConservativeMind

One should be able to get rid of a fatty liver with diet, getting somewhere below 15% body fat, otherwise.


5 posted on 05/02/2022 11:48:27 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

My liver be phat.

6 posted on 05/02/2022 11:48:33 AM PDT by martin_fierro (< |:)~)
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To: ConservativeMind
and one supplement, Pantethine,

How much of the supplement and for how long was the treatment?

7 posted on 05/02/2022 11:55:49 AM PDT by frogjerk (I will not do business with fascists)
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To: ConservativeMind

I wash my liver every night with alcohol...............


8 posted on 05/02/2022 11:56:08 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: frogjerk

They were on it five months before being retested.

The link I provided gives more detail, but it was 300 mg, twice a day.


9 posted on 05/02/2022 11:58:39 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

10 posted on 05/02/2022 12:07:28 PM PDT by Sans-Culotte (11/3-11/4/2020 - The USA became a banana republic.)
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To: All

The VA tells me weight loss and carb reduction are the only approved concepts for both Non Alcohol Fatty Liver Disease, and its progression to Non Alcohol Steatoheptitis.

Heads up people. Things have changed.

As of today, most cirrhosis cases are not from hepatitis virus or from alcohol. It’s from high fat diets, even if overall weight has not sharply increased. You can form cirrhosis with zero alcohol and zero Hep A, B, C virus. NAFLD is going to soon be the primary reason behind liver transplants.

Now, most have not just eaten high fat diets, they have also gained weight. Weight loss of 10% of body weight is the only study out there showing reduction of liver fat totals.

There is an intermediate stage between fatty liver and cirrhosis. That is NASH. This will start to form fibrosis structures the liver is not repairing. It has not yet reached cirrhosis stage but it is headed there. Weight loss and diet restriction of sugar and saturated fat is the only treatment with proper studies behind it for this, and those studies suggest about all that can be reasonably done is stop progression to cirrhosis.

Meaning reversal of fat is very possible, but it takes years to reverse the fibrosis.

There are many drugs in development because fat in liver has become an epidemic. 30-40% of the population has it, and they are not all obese. To date, none have passed their clinical trials. One promising type was rejected by FDA at Phase III.

A drug will eventually get developed and it will actually stop/reverse cirrhosis, but not yet.


11 posted on 05/02/2022 12:07:43 PM PDT by Owen
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To: ConservativeMind

In other news, psychologists have determined that completely eliminating bacon and pastrami from one’s diet can lead to long stretches of depression and despair.


12 posted on 05/02/2022 12:15:18 PM PDT by who_would_fardels_bear (This is not a tagline.)
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To: ConservativeMind

I bequeath my Foi Grais to humanity....


13 posted on 05/02/2022 12:23:51 PM PDT by FreshPrince
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To: ConservativeMind

I have it. I have the genetic propensity for it as per 23andme.

If you want to check for it growthfactor15 test may be an indication.


14 posted on 05/02/2022 12:29:46 PM PDT by RummyChick
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To: ConservativeMind

Thanks!


15 posted on 05/02/2022 12:30:45 PM PDT by frogjerk (I will not do business with fascists)
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To: ConservativeMind
At the outset of a diagnosis of NAFLD, the patient should seek a sleep study to rule out sleep apnea.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937104/

16 posted on 05/02/2022 12:50:41 PM PDT by Seaplaner (Never give in. Never give in. Never, never, never...in nothing, great or small...Winston Churchill)
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To: ConservativeMind

Sadly, a close friend of mine died several years ago of severe NAFLD. Although relatively mild cases are common, NAFLD is a spectrum disorder with severe cases all too common.


17 posted on 05/02/2022 1:13:52 PM PDT by Rockingham
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To: ConservativeMind

Read that study some months ago. I have fatty liver so decent to try the Pantethine. 600 mg per day now for 3 months. Had blood work done back in October of last year. Cholesterol was 205. Blood work again this March. Cholesterol was 174. Ratio of good to bad cholesterol was 2.7 /1. Anything under 5 to 1 is acceptable. 3.5 to 1 is optimal. No other changes in lifestyle. My observation is that the Pantethine works.


18 posted on 05/02/2022 1:52:37 PM PDT by technically right
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To: ConservativeMind

I recommend heavy alcohol consumption, so you can go right past fatty liver disease, and relax with cirrhosis..


19 posted on 05/02/2022 2:09:01 PM PDT by EEGator
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To: technically right

Any adverse interactions with other meds…side effects?


20 posted on 05/02/2022 3:16:56 PM PDT by sanjuanbob
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