Posted on 05/01/2022 4:47:19 PM PDT by ConservativeMind
Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study.
Non-obstructive coronary artery disease occurs when there is less than 50% stenosis, or narrowing, of the coronary arteries due to plaque buildup. Coronary CT angiography (CCTA) is often recommended as a first-line test to detect plaque.
Medications called statins are commonly prescribed for patients who are diagnosed with non-obstructive coronary artery disease. Statins reduce the production of low-density lipoprotein (LDL) cholesterol and draw cholesterol out of plaque, therefore stabilizing the plaque and reducing the risk of it rupturing. Aspirin is another drug that is commonly recommended. However, not much research has been done to determine whether aspirin is effective at reducing major cardiovascular events in patients with non-obstructive coronary artery disease.
A total of 3,571 (56%) of the patients included in the study had no plaque and 2,815 (44%) had non-obstructive coronary artery disease.
Baseline aspirin and statin use were documented for both groups. In individuals with nonobstructive coronary artery disease, aspirin therapy was not associated with a reduction in major adverse cardiovascular events. Alternatively, statin use was associated with a significant reduction in cardiovascular events, including heart attack and death.
"Our findings build on prior analyses from the CONFIRM registry at 2.3-year follow-up which called into question the utility of aspirin in the setting of CCTA diagnosed atherosclerosis," Dr. Leipsic said.
Neither aspirin nor statin therapy improved clinical outcomes for patients with no detectable plaque. Aspirin therapy may still be beneficial in cases of high-risk plaque or high plaque burden, Dr. Leipsic said.
"Ultimately, further research is required to determine whether, and at what threshold, clinicians should consider prescribing aspirin for patients upon the identification of non-obstructive coronary artery disease on coronary CT angiography," he said.
(Excerpt) Read more at medicalxpress.com ...
I cannot tolerate statins. I have kept my numbers good with OTC niacin and red rice yeast oer my MD’s instructions.
I’m on 80mg Atorvastatin and 81mg coated Aspirin, plus 97/103 Entresto. Ticker’s working fine, as of last week’s ECHO.
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You do know that red yeast rice contains lovastatin?
Aspirin is an acquired taste.
It is always fun to see peoples faces when you claim they are giving you a headache throw a few aspirin in your mouth and chew them loudly.
When I was a little kid, I thought those orange flavored ones tasted just dandy!
I call BS on the Statin claims. Draw out plague my ass.
Define non obstructive coronary disease. The only one I know of is coronary artery spasm, (usually found with cocaine or meth use) this is not a common occurrence. Other types of heart problems are usually related to arrhythmias, which will not be affected by aspirin. Or cardiomyopathies which can occur for a number of different reasons. Aspirin is still the best defense against strokes or typical coronary artery obstruction. Just my two cents. Coming from working in Cardiology for over thirty years.
Yes and Yes,
THIS !
Thanks! Good to know.
Had a stroke 3 years ago. Dr. prescribed 80mg of asprin daily. Ignored and have been using Nattokinse, vitaminD3, occasionally vitamin K, and other supplements.
The medical problems really start after people start taking statins. I assume this is all about convincing people to take them so that the drug companies can make more money.
I don’t know the dosage, but I take one to two adult aspirin daily as it helps me recover from extensive exercise.
I also take statins.
I think the combo of both is the best course, and ask why didn’t they have a third group that took both drugs... and with a larger dosage of aspirin...
Helps with stroke though. So maybe still a good idea to take one a day.
Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study.
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Still other studies show that, instead of lengthening life, statins shorten life.
The disease used to be called “hardening of the arteries”. It happens when arteries are incapable of expanding and contracting when the heart pumps. It is cause by sugar glycation and sugar-caused bleaching of the artery walls.
It’s tempting to be sarcastic here, but the solution is obvious.
(any (dim) carbon unit with a marginally functioning brain & synaptic response capacity, after these last 2 years of COVID-19 hyperbolical scatology),
can attribute these questionable results to alleged medical professionals who manipulated and wanted to conceal for 75 years the data of this present Extinction Level Event (ELE).
So I will continue to take 81mg of ASA.
Actually, it does. As an antiinflamatory Aspirin daily has several benefits including the eliminating formation of inflammatory arterial plaque that produces heart disease.
My testimony is that aspirin removes the likely hoot of heart attack or stroke.
At some point, aspirin promotes purpling arms as bruising become more likely
I believe this study is completely silent on stroke issues.
At 83 I am in generally good health. I have been taking various vitamins, minerals, and other supplements for around 50 years. I began taking 81 mg aspirin about a decade ago. In my annual physical at Kaiser Permanente my doctor listens to my heart but never indicates there is a problem. He looks at my cholesterol and says I should take statins. I said no, I eat a healthy diet, am below 25 BMI, no diabetes, never smoked, and seldom drink, most relatives died between 90 and 103. The only other thing he is concerned about is my low GFI. I think the problem might be that I restrict water before I go for my exam and blood work so I don’t leak by accident. Next time I will drink a lot of water and wear a pad. Am I running a risk with aspirin and no statins?
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