Posted on 01/06/2022 12:43:22 PM PST by Red Badger
It may be a respiratory disease, but COVID-19 impacts more than just the lungs. A whole host of vital organs can be affected, including the kidneys, and a recent study has finally worked out how.
SARS-CoV-2 – the virus that causes COVID-19 – can infect and directly damage the kidneys by causing scarring, according to research in the journal Cell Stem Cell. The resulting scar tissue could have long-term impacts on kidney function, the authors say.
While the ability of the virus to bind and infect kidney cells is old news, the finer details of what exactly causes damage have until now eluded scientists. This latest finding provides another “piece of the puzzle,” lead author Jitske Jansen of Radboud University Medical Center said in a statement.
In 2020, a study found that up to 50 percent of hospitalized COVID-19 patients experienced renal failure, with up to 10 percent requiring dialysis. Last year, a study of almost 90,000 COVID-19 survivors found them to be at greater risk of kidney damage than people who had never had COVID.
“Our work shows kidney scarring in COVID-19 patients, which provides an explanation why the virus might cause kidney functional decline as demonstrated in other studies,” co-author Katharina Reimer of RWTH Aachen Uniklinik said.
The team collected tissue samples from 62 COVID-19 patients admitted to the Intensive Care Unit (ICU). When compared to the control groups – ICU patients with a non-COVID-related lung infection and a group of healthy people – the tissue from COVID-19 patients showed substantially more scarring.
To identify whether the tissue damage was directly caused by the virus, as opposed to inflammation or other systemic effects, the team created “mini kidneys”. Also called “organoids”, they were cultured in the lab from stem cells, containing many different types of kidney cells, with the notable exception of immune cells. Once infected with SARS-CoV-2, the mini kidneys, like the COVID-19 patients’ tissues, became scarred. The team also found evidence of signaling molecules known to be involved in the scarring process.
“In our study, we thoroughly investigated the causal damaging effects of the Coronavirus in the kidneys. [We] show that the virus directly causes cell damage, independent of the immune system,” Jansen added.
All of this strongly suggests that the virus itself is directly responsible for the observed tissue damage.
Kidney fibrosis (scarring) can have serious long-term health implications, Reimer said, adding that further research is needed.
“Long-term follow-up studies will provide further insights into kidney-related pathologies caused by SARS-CoV-2,” she concluded.
And why haven’t we punished China for this? Don’t answer. It was rhetorical.
*talks to kidneys* DO YOU HEAR THAT? IT’S NOT THE ALCOHOL!!!
Kristi’s Kidneys: Will someone please help us....? *cough, cough*
Are they providing cover for Remdesivir’s kidney damage?
likely.
yes.
Yep RunDeathIsNear
Covid is going to have to take a number and stand in line to get a whack at my kidneys.
a wonderful patent for the CDC.
oh the royalties that they made.
from their DNA operating sys ... i mean “vaccine”, too.
gobs of money. no accountability.
death incoming and MSM is silent as professionals
die on field during performance.
as children die of diseases of 90 year olds.
silence.
no accountability.
only. MORE MANDATE.
Still not gettin’ a shot
That came to my mind also....
Wouldn’t surprise me.
Can we make sure this bio weapon attacks the organs?
Shay shay
COVID-19 and Vitamin D | Association Between Vitamin D Deficiency and COVID-19 [Sunday, 01/31/2021; video by Zach Murphy] https://www.youtube.com/watch?v=cT1CaTv5-e4
>>Are they providing cover for Remdesivir’s kidney damage?<<
Great observation...great post!
“Are they providing cover for Remdesivir’s kidney damage?”
totally ... i know dozens of folks who had test-verified and symptomatic covid, and not a single one of them has complained to me about “long covid”, kidney damage, or anything else potentially covid-related ...
That was the point of this ex-vivo study, to determine how kidney tissue responds to the virus in the absence of an immune response. The result showed cellular damage and fibrosis was directly caused by the virus.
But your point about the immune/inflammatory response in general causing great damage and mortality is certainly well documented.
There was a recent study in Germany that followed up on (mostly mild to moderate) recovered patients 9 months after recovery, and found widespread organ damage. All of these patients were pre-vaccine, so it was definitely the virus. There are going to be long term impacts on our healthcare system from this virus.
One of the recommendations from the study is for people to have systematic organ screening performed 6-9 months after recovery from COVID. Heart, lungs, liver, kidneys.
Thanks for the link; I am actually trying to read the PDF file. The “phenotype” term, details, esp.
A couple of files (from my stack of stuff) that may interest you, or for your collection:
Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients
https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00606
Physical phenotype of blood cells is altered in COVID-19
https://www.sciencedirect.com/science/article/pii/S0006349521004549?via%3Dihub
And, Mobeen Syed, MD explanation: “COVID-19 Causes Long-Term Blood Cell Changes”:
https://www.youtube.com/watch?v=721WMC5pZ5A
A couple of files (from my stack of stuff) that may interest you, or for your collection:
Evidence of Structural Protein Damage and Membrane Lipid Remodeling in Red Blood Cells from COVID-19 Patients
https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00606
Physical phenotype of blood cells is altered in COVID-19
https://www.sciencedirect.com/science/article/pii/S0006349521004549?via%3Dihub
And, Mobeen Syed, MD explanation: “COVID-19 Causes Long-Term Blood Cell Changes”:
https://www.youtube.com/watch?v=721WMC5pZ5A
.
It seems to me that if it damages kidneys, what other organs are affected just as badly?
What about fertility in men and women?
What if they cause cancers in 5-10 years?.......................
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