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Bombshell: The Leaky Vaccine Breakthrough Variant Is Here
https://noqreport.com ^ | Oct 26th, 2021 | by Dr. Joseph Mercola

Posted on 10/26/2021 9:19:54 AM PDT by Red Badger

STORY AT-A-GLANCE

High COVID vaccination rates create pressure on the virus to mutate into variants with higher levels of contagion and pathogenicity. Recent research concluded that those who are fully “vaccinated” against COVID-19 are indeed more susceptible to COVID variant infections than unvaccinated people

The narrow protection you get from the COVID shot will inevitably necessitate a booster shot for each emerging new variant that is resistant to the shots

U.K. data show the COVID death toll is higher among the fully vaccinated compared to the unvaccinated. Between February 1, 2021, and September 12, 2021, 63.5% of those who died from COVID-19 within 28 days of a positive test were fully vaccinated

Infection-enhancing anti-SARS-CoV-2 antibodies now recognize both the original Wuhan/D614G strain and Delta variants, which suggests antibody-dependent enhancement (ADE) is emerging

Israeli research shows antibody levels rapidly decrease after the second dose of Pfizer’s COVID shot. IgG antibodies — which are part of your humoral immune response — decreased at a consistent rate over time, whereas the neutralizing antibodies rapidly decreased during the first three months, and then slowed down thereafter

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It was only a matter of time before a vaccine-resistant strain of COVID-19 would surface, and that time has already come to pass. As reported by The Conservative Treehouse October 3, 2021:1

“What this study2 finds is exactly what vaccine developer Geert Vanden Bossche (Belgium) has been predicting. The predominance of antibody-resistant SARS-Cov-2 variants in vaccine breakthrough cases from the San Francisco Bay Area, California …

Dr. Vanden Bossche has been using Israeli data and showing3 how the widespread vaccination rates were creating pressure on the virus to mutate into variants with higher levels of contagion.

The unvaccinated group has been keeping the pressure down by defeating the virus and carrying natural immunity. However, as the unvaccinated population is increasingly made smaller, the pressure on the virus to mutate increases. Subsequently, these mutations stay at higher or more effective levels of infection.”

Vaccine-Evading Variants Are Emerging

The study, posted on the preprint server medRxiv, August 25, 2021, concluded that those who are fully “vaccinated” against COVID-19 are in fact more susceptible to COVID variant infections than unvaccinated people.

Vanden Bossche’s theory was that vaccine antibodies would suppress natural antibody responses, allowing variants to slip through, and this seems to be what’s happening. As explained by The Conservative Treehouse October 3, 2021:4

“Among vaccinated individuals, a COVID variant virus is not recognized by the specialized antibodies provided by the vaccine, and the natural antibodies have been programmed to stand down.”

According to the authors of the study:5

“Associations between vaccine breakthrough cases and infection by SARS coronavirus 2 (SARS-CoV-2) variants have remained largely unexplored. Here we analyzed SARS-CoV-2 whole-genome sequences and viral loads from 1,373 persons with COVID-19 from the San Francisco Bay Area from February 1 to June 30, 2021, of which 125 (9.1%) were vaccine breakthrough infections.

Fully vaccinated were more likely than unvaccinated persons to be infected by variants carrying mutations associated with decreased antibody neutralization (78% versus 48%), but not by those associated with increased infectivity (85% versus 77%) …

These findings suggest that vaccine breakthrough cases are preferentially caused by circulating antibody-resistant SARS-CoV-2 variants, and that symptomatic breakthrough infections may potentially transmit COVID-19 as efficiently as unvaccinated infections, regardless of the infecting lineage.”

“Be careful around vaccinated people, because they can carry a more resistant form of COVID-19,” The Conservative Treehouse warns, adding that the narrow protection you get from the COVID shot will inevitably necessitate a booster shot for each emerging new variant that is resistant to the shots.

UK Data Show Increased COVID Mortality Among Fully Vaxxed

British data also raise serious questions about the wisdom of this injection campaign. In its Technical Briefing 23,6 published September 17, 2021, Public Health England reveals data showing the COVID death toll is actually higher among the fully vaccinated compared to the unvaccinated.

Between February 1, 2021, and September 12, 2021, 157,400 fully vaccinated patients (26.52% of total cases) were diagnosed with a Delta variant. Among the unvaccinated, there were 257,357 Delta variant cases (43.36% of total cases).

However, while Delta infections were far more prevalent among the unvaccinated, these patients also had better outcomes. In all, 63.5% of those who died from COVID-19 within 28 days of a positive test were fully vaccinated (1,613 compared to 722 in the unvaccinated group).

More Signs of Antibody-Dependent Enhancement

In a letter to the editor of the Journal of Infection,7 published August 9, 2021, three researchers point out that “infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants,” which suggests antibody-dependent enhancement (ADE) is emerging. According to the authors:8

“Antibody dependent enhancement (ADE) of infection is a safety concern for vaccine strategies. In a recent publication, Li et al. (Cell 184 :4203–4219, 2021) have reported that infection-enhancing antibodies directed against the N-terminal domain (NTD) of the SARS-CoV-2 spike protein facilitate virus infection in vitro, but not in vivo.

However, this study was performed with the original Wuhan/D614G strain. Since the Covid-19 pandemic is now dominated with Delta variants, we analyzed the interaction of facilitating antibodies with the NTD of these variants … [W]e show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs …

As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain.

However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity. Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).”

As noted by independent journalist Sharyl Attkisson,9 “Despite the fact that multiple medical authorities predicted, told us, and hoped, ADE would not impact Covid-19 vaccines, data from the study indicates it has done just that.”

Antibody Levels Decrease After Second Dose

While you’re not considered “fully vaccinated” until 14 days after your first dose of Janssen’s or AstraZeneca’s shot, or second dose of Moderna’s or Pfizer’s, a recent Israeli study found antibody levels actually decrease after the second dose of Pfizer’s COVID shot. The findings were reported by The Jerusalem Post, October 7, 2021:10

“Antibody levels decrease rapidly after two doses of the Pfizer coronavirus vaccine, a study11 by researchers at the Sheba Medical Center published … in the New England Journal of Medicine …

The research also showed the probability that different groups of individuals — based on age and general health status — will find themselves below a certain antibody threshold after a period of six months.”

In all, 4,868 staff members at the Sheba Medical Center participated in the study,12 undergoing monthly serological tests to measure their antibodies for up to six months after their second Pfizer shot.

Buy your Gold and Silver from true America-First patriots. Contact Our Gold Guy and protect yourself through the coming (and current) economic turmoil. Everyone, regardless of age or gender, saw a rapid decline in their antibodies after the second dose. IgG antibodies — which are part of your humoral immune response — decreased at a consistent rate over time, whereas the neutralizing antibodies rapidly decreased during the first three months, and then slowed down thereafter. According to the authors:13

“Although IgG antibody levels were highly correlated with neutralizing antibody titers (Spearman’s rank correlation between 0.68 and 0.75), the regression relationship between the IgG and neutralizing antibody levels depended on the time since receipt of the second vaccine dose …

The highest titers after the receipt of the second vaccine dose (peak) were observed during days 4 through 30, so this was defined as the peak period.

The expected geometric mean titer (GMT) for IgG for the peak period, expressed as a sample-to-cutoff ratio, was 29.3. A substantial reduction in the IgG level each month, which culminated in a decrease by a factor of 18.3 after 6 months, was observed.

Neutralizing antibody titers also decreased significantly, with a decrease by a factor of 3.9 from the peak to the end of study period 2, but the decrease from the start of period 3 onward was much slower, with an overall decrease by a factor of 1.2 during periods 3 through 6. The GMT of neutralizing antibody, expressed as a 50% neutralization titer, was 557.1 in the peak period and decreased to 119.4 in period 6 …

Six months after receipt of the second dose, neutralizing antibody titers were substantially lower among men than among women, lower among persons 65 years of age or older than among those 18 to less than 45 years of age, and lower among participants with immunosuppression than among those without immunosuppression.”

COVID-19 Unrelated to Jab in 68 Countries, 2,947 US Counties The Israeli findings above can help explain the findings of a study14 published September 30, 2021, in the European Journal of Epidemiology, which found no relationship between COVID-19 cases and levels of vaccination in 68 countries worldwide and 2,947 counties in the U.S. If anything, areas with high vaccination rates had slightly higher incidences of COVID-19. According to the authors:15

“[T]he trend line suggests a marginally positive association such that countries with higher percentage of population fully vaccinated have higher COVID-19 cases per 1 million people.”

Iceland and Portugal, for example, where more than 75% of their populations are fully vaccinated, had more COVID-19 cases per 1 million people than Vietnam and South Africa, where only about 10% of the populations are fully vaccinated.16

Data from U.S. counties showed the same thing. New COVID-19 cases per 100,000 people were “largely similar,” regardless of the percentage of a state’s population that was fully vaccinated.

“There … appears to be no significant signaling of COVID-19 cases decreasing with higher percentages of population fully vaccinated,” the authors wrote.17 Notably, out of the five U.S. counties with the highest vaccination rates — ranging from 84.3% to 99.9% fully vaccinated — four of them were on the U.S. Centers for Disease Control and Prevention’s “high transmission” list. Meanwhile, 26.3% of the 57 counties with “low transmission” have vaccination rates below 20%.

The study even accounted for a one-month lag time that could occur among the fully vaccinated, since it’s said that it takes two weeks after the final dose for “full immunity” to occur. Still, “no discernable association between COVID-19 cases and levels of fully vaccinated” was observed.18

Key Reasons Why Reliance on Jabs Should Be Reexamined

The study summed up several reasons why the “sole reliance on vaccination as a primary strategy to mitigate COVID-19” should be reevaluated. For starters, the jab’s effectiveness is rapidly waning.

“A substantial decline in immunity from mRNA vaccines six months’ post immunization has … been reported,” the researchers noted, adding that even severe hospitalization and death from COVID-19, which the jabs claim to protect against, have increased from 0.01% to 9% and 0% to 15.1%, respectively, among the fully vaccinated from January 2021 to May 2021.19

If the jabs work as advertised, why haven’t these rates continued to rise instead of fall? “It is also emerging,” the researchers noted, “that immunity derived from the Pfizer-BioNTech vaccine may not be as strong as immunity acquired through recovery from the COVID-19 virus.”20

Natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. ~ T. Patalon et.al. August 2021 For instance, a retrospective observational study published August 25, 2021, revealed that natural immunity is superior to immunity from COVID-19 jabs. According to the authors:21

“This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity.”

Reinfection Is Very Rare

The fact is, while breakthrough cases continue among those who have gotten one or more COVID-19 injections, it’s extremely rare to get COVID-19 after you’ve recovered from the infection. How rare? Researchers from Ireland conducted a systematic review including 615,777 people who had recovered from COVID-19, with a maximum duration of follow-up of more than 10 months.22

“Reinfection was an uncommon event,” they noted, “with no study reporting an increase in the risk of reinfection over time.” The absolute reinfection rate ranged from 0% to 1.1%, while the median reinfection rate was just 0.27%.23,24,25

Another study revealed similarly reassuring results. It followed 43,044 SARS-CoV-2 antibody-positive people for up to 35 weeks, and only 0.7% were reinfected. When genome sequencing was applied to estimate population-level risk of reinfection, the risk was estimated at 0.1%.26

There was no indication of waning immunity over seven months of follow-up, unlike with the COVID-19 injection, which led the researchers to conclude that “Reinfection is rare. Natural infection appears to elicit strong protection against reinfection with an efficacy >90% for at least seven months.”27

All Risk for No Reward?

The purpose of informed consent is to give people all of the data related to a medical procedure so they can make an educated decision before consenting. In the case of COVID-19 injections, such data initially weren’t available, given their emergency authorization, and as concerning side effects became apparent, attempts to share them publicly were suppressed.

In August 2021, a large study from Israel28 revealed that the Pfizer COVID-19 mRNA jab is associated with a threefold increased risk of myocarditis,29 leading to the condition at a rate of one to five events per 100,000 persons.30 Other elevated risks were also identified following the COVID-19 jab, including lymphadenopathy (swollen lymph nodes), appendicitis and herpes zoster infection.31

Dr. Peter McCullough, an internist, cardiologist and epidemiologist, is among those who have warned that COVID-19 injections are not only failing but putting lives at risk.32

According to McCullough, by January 22, 2021, there had been 186 deaths reported to the Vaccine Adverse Event Reporting System (VAERS) database following COVID-19 injection — more than enough to reach the mortality signal of concern to stop the program.

“With a program this size, anything over 150 deaths would be an alarm signal,” he said. The U.S. “hit 186 deaths with only 27 million Americans jabbed.” McCullough believes if the proper safety boards had been in place, the COVID-19 jab program would have been shut down in February 2021 based on safety and risk of death.33

Now, with data showing no difference in rates of COVID-19 cases among the vaxxed and unvaxxed, it appears more and more likely that the injections have a high level of risk with very little reward, especially among certain populations, like youth.

Mass Vaccination Drives Mutations It’s well-known that if you put living organisms like bacteria or viruses under pressure, via antibiotics, antibodies or chemotherapeutics, for example, but don’t kill them off completely, you can inadvertently encourage their mutation into more virulent strains. Those that escape your immune system end up surviving and selecting mutations to ensure their further survival.

Many have warned about immune escape due to the pressure being placed upon the COVID-19 virus during mass vaccination,34 and according to one mathematical model,35 a worst-case scenario can develop when a large percentage of a population is vaccinated but viral transmission remains high, such as it is now. This is a prime scenario for the development of resistant mutant strains.36

At this point, COVID-19 injection failures and serious jab-related health risks are both apparent. We now also have data showing that having a high vaccination rate does nothing to lower COVID-19 incidence.

It might actually increase it slightly, as we’re seeing in India. In Kerala, India, which boasts a 93% vaccination rate, more than half of all new COVID cases are fully vaccinated, as are 57% of COVID-related deaths.37 With all data pointing in the same direction, it’s clear that COVID shots aren’t the answer. As noted in the European of Journal of Epidemiology:38

“Stigmatizing populations can do more harm than good. Importantly, other non-pharmacological prevention efforts (e.g., the importance of basic public health hygiene with regards to maintaining safe distance or handwashing, promoting better frequent and cheaper forms of testing) needs to be renewed in order to strike the balance of learning to live with COVID-19 in the same manner we continue to live a 100 years later with various seasonal alterations of the 1918 Influenza virus.”

If You’re ‘Vaccinated’ You May Be High-Risk for COVID As predicted from the very beginning of the mass vaccination campaign, we’re now starting to see evidence of ADE, which makes people more prone to serious illness rather than less.

Even if your risk for ADE is small (and we have no data on prevalence as of yet), the data we do have suggest the shots aren’t ending outbreaks, and indeed can’t, end them, as it’s the vaccinated who are facilitating the emergence of vaccine-evading variants. The real answer is natural herd immunity, as natural immunity protects against most variants and not just one.

To be on the safe side, I recommend considering yourself “high-risk” for severe COVID if you’ve received one or more shots, and implement known effective treatment at the first sign of a respiratory infection.

Options include the Zelenko protocol,39 the MATH+ protocols40 and nebulized hydrogen peroxide, as detailed in Dr. David Brownstein’s case paper.41 Whichever treatment protocol you use, make sure you begin treatment as soon as possible, ideally at first onset of symptoms.

Our Gold Guy America First “The Truth About COVID-19” exposes the hidden agenda behind the pandemic, showing the countermeasures have nothing to do with public health and everything to do with ushering in a new social and economic system based on totalitarian, technocracy-led control. So, it’s not misinformation they fear. It’s the truth they want to prevent from spreading. Pick up a copy of this best-selling book today before it’s too late.

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1, 4 Conservative Treehouse October 3, 2021

2, 5 medRxiv August 25, 2021, DOI: 10.1101/2021.08.19.21262139

3 YouTube Vejon Health Vanden Bosche and Robert Malone interview

6 Public Health England Technical Briefing 23, September 17, 2021

7, 8 Journal of Infection Letter to the Editor August 9, 2021

9 Sharyl Attkisson August 17, 2021

10 The Jerusalem Post October 7, 2021

11, 12, 13 NEJM October 6, 2021 DOI: 10.1056/NEJMoa2114583

14, 15, 16, 17, 18, 19, 20, 38 European Journal of Epidemiology September 30, 2021

21 medRxiv August 25, 2021

22, 23 Rev Med Virol. 2021;e2260

24 The Blaze July 14, 2021

25 News Rescue July 15, 2021

26, 27 medRxiv January 15, 2021

28, 30, 31 The New England Journal of Medicine August 25, 2021

29 MedPage Today August 25, 2021

32 BitChute, Episode 20 of Perspectives on the Pandemic: The Dangers of the Injections, August 26, 2021

33, 34 BitChute, Episode 20 of Perspectives on the Pandemic, ‘This Interview Could Save Your Life’ Part Two: The Dangers of the Injections, August 26, 2021

35, 36 Scientific Reports July 30, 2021

37 Onmanorama.com October 12, 2021

39 Zelenko protocol

40 Covid19criticalcare.com

41 Science, Public Health Policy and The Law July 2020; 1: 4-22 (PDF)


TOPICS: Business/Economy; Health/Medicine; Science; Society
KEYWORDS: ade; anthonyfauci; chinavirus; covidstooges; geert; obamacare; vaccinemandates; vandenbossche; variant; vaxx; vaxxx
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To: House Atreides
OK… give it to us straight… we can take it. How much longer before we vaccinated FReepers begin our ADE die-off?

Nobody wants that. But the stats out of the UK, Israel and other places are not looking positive. If this is what "safe and effective" looks like, I'd hate to see "unsafe and ineffective."
41 posted on 10/26/2021 12:02:52 PM PDT by Antoninus (Republicans are all honorable men.)
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To: House Atreides

OK… give it to us straight… we can take it. How much longer before we vaccinated FReepers begin our ADE die-off?
—_______
Ask the VA about the Gulf War 1 adverse reactions to the Anthrax jab, I know 2 on permanent disability, death is not your concern , permanent disability 6-10 years down the road should be. Some things are worse than death….at least the VA is providing care and disability checks- do you think Moderna and Pfitzer will?….the first Red flag was legal immunity granted to the drug companies…the second is the huge amount of side effects….


42 posted on 10/26/2021 12:32:11 PM PDT by delta7
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To: delta7

….the third Red flag is unconstitutional mandates…all for a virus that is 99.8 percent survivable…..in my small backyard, I know 7 people with horrific side effects- one 74 year old died from the jab. I at 63 had the C flu- no biggy. Why is everyone so fearful of the C flu? Time is beginning to tell a terrible story, best you get on your knees and pray for discernment, grace and mercy.


43 posted on 10/26/2021 12:40:55 PM PDT by delta7
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To: delta7

You would do well to watch the Cspan hearings today, MSM will not report it, the stories of side effects are heart wrenching.


44 posted on 10/26/2021 12:44:02 PM PDT by delta7
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To: pepsi_junkie

There are studies on natural immunity showing it is effective against variants, the shot, not so much.


45 posted on 10/26/2021 12:49:50 PM PDT by LilFarmer
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To: Red Badger
Reposting natural immunity studies for those who may have missed it:

One-year sustained cellular and humoral immunities of COVID-19 convalescents “SARS-CoV-2-specific IgG antibodies, and also NAb can persist among over 95% COVID-19 convalescents from 6 months to 12 months after disease onset. At least 19/71 (26%) of COVID-19 convalescents (double positive in ELISA and MCLIA) had detectable circulating IgM antibody against SARS-CoV-2 at 12m post-disease onset. Notably, the percentages of convalescents with positive SARS-CoV-2-specific T-cell responses (at least one of the SARS-CoV-2 antigen S1, S2, M and N protein) were 71/76 (93%) and 67/73 (92%) at 6m and 12m, respectively. Furthermore, both antibody and T-cell memory levels of the convalescents were positively associated with their disease severity.”

Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections “Our analysis demonstrates that SARS-CoV-2-naïve vaccinees had a 13.06-fold increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant for a symptomatic disease as well…. This analysis demonstrated that natural immunity affords longer lasting and stronger protection against infection, symptomatic disease and hospitalization due to the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity.”

Shedding of Infectious SARS-CoV-2 Despite Vaccination “The SARS-CoV-2 Delta variant might cause high viral loads, is highly transmissible, and contains mutations that confer partial immune escape. Outbreak investigations suggest that vaccinated persons can spread Delta.

Necessity of COVID-19 vaccination in previously infected individuals, by  “Individuals who have had SARS-CoV-2 infection are unlikely to benefit from COVID-19 vaccination, and vaccines can be safely prioritized to those who have not been infected before.”

Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection “This study demonstrates individuals who received the Pfizer-BioNTech mRNA vaccine have different kinetics of antibody levels compared to patients who had been infected with the SARS-CoV-2 virus, with higher initial levels but a much faster exponential decrease in the first group.”

Discrete Immune Response Signature to SARS-CoV-2 mRNA Vaccination Versus Infection. “In COVID-19 patients, immune responses were characterized by a highly augmented interferon response which was largely absent in vaccine recipients.” 

SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. “This study sought to determine whether infection with SARS-CoV-2 induces antigen-specific long-lived BMPCs in humans. We detected SARS-CoV-2 S-specific BMPCs in bone marrow aspirates from 15 out of 19 convalescent individuals, and in none from the 11 control participants…. Overall, our results are consistent with SARS-CoV-2 infection eliciting a canonical T-cell-dependent B cell response, in which an early transient burst of extrafollicular plasmablasts generates a wave of serum antibodies that decline relatively quickly. This is followed by more stably maintained levels of serum antibodies that are supported by long-lived BMPCs.”

Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells “ We evaluated 254 COVID-19 patients longitudinally from early infection and for eight months thereafter and found a predominant broad-based immune memory response. SARS-CoV-2 spike binding and neutralizing antibodies exhibited a bi-phasic decay with an extended half-life of >200 days suggesting the generation of longer-lived plasma cells. In addition, there was a sustained IgG+ memory B cell response, which bodes well for a rapid antibody response upon virus re-exposure.”

Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine”Natural infection induced expansion of larger CD8 T cell clones occupied distinct clusters, likely due to the recognition of a broader set of viral epitopes presented by the virus not seen in the mRNA vaccine.”

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection “We analyzed multiple compartments of circulating immune memory to SARS-CoV-2 in 254 samples from 188 COVID-19 cases, including 43 samples at ≥ 6 months post-infection. IgG to the Spike protein was relatively stable over 6+ months. Spike-specific memory B cells were more abundant at 6 months than at 1 month post symptom onset. SARS-CoV-2-specific CD4+ T cells and CD8+ T cells declined with a half-life of 3-5 months.”

Persistence of neutralizing antibodies a year after SARS-CoV-2 infection “We assessed the persistence of serum antibodies following wild-type SARS-CoV-2 infection six and twelve months after diagnosis in 367 individuals of whom 13% had severe disease requiring hospitalization. We determined the SARS-CoV-2 spike (S-IgG) and nucleoprotein IgG concentrations and the proportion of subjects with neutralizing antibodies (NAb).”

Quantifying the risk of SARS‐CoV‐2 reinfection over time “Reinfection was an uncommon event (absolute rate 0%–1.1%), with no study reporting an increase in the risk of reinfection over time. Only one study esti- mated the population‐level risk of reinfection based on whole genome sequencing in a subset of patients; the estimated risk was low (0.1% [95% CI: 0.08–0.11%]) with no evidence of waning immunity for up to 7 months following primary infection. These data suggest that naturally acquired SARS‐CoV‐2 immunity does not wane for at least 10 months post‐infection.”

SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy “Reinfection is rare in the young and international population of Qatar. Natural infection appears to elicit strong protection against reinfection with an efficacy ~95% for at least seven months.”

Natural immunity against COVID-19 significantly reduces the risk of reinfection: findings from a cohort of sero-survey participants “These findings reinforce the strong plausibility that development of antibody following natural infection not only protects against re-infection by the virus to a great extent, but also safeguards against progression to severe COVID-19 disease.”

Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection: A three-month nationwide experience from Israel “Similarly, the overall estimated level of protection from prior SARS-CoV-2 infection for documented infection is 94·8% (CI:[94·4, 95·1]); hospitalization 94·1% (CI:[91·9, 95·7]); and severe illness 96·4% (CI:[92·5, 98·3]). Our results question the need to vaccinate previously-infected individuals.”

Immune Memory in Mild COVID-19 Patients and Unexposed Donors Reveals Persistent T Cell Responses After SARS-CoV-2 Infection “Using HLA class II predicted peptide megapools, we identified SARS-CoV-2 cross-reactive CD4+ T cells in around 66% of the unexposed individuals. Moreover, we found detectable immune memory in mild COVID-19 patients several months after recovery in the crucial arms of protective adaptive immunity; CD4+ T cells and B cells, with a minimal contribution from CD8+ T cells. Interestingly, the persistent immune memory in COVID-19 patients is predominantly targeted towards the Spike glycoprotein of the SARS-CoV-2. This study provides the evidence of both high magnitude pre-existing and persistent immune memory in Indian population.”

Live virus neutralisation testing in convalescent patients and subjects vaccinated against 19A, 20B, 20I/501Y.V1 and 20H/501Y.V2 isolates of SARS-CoV-2 “Interestingly, a significant difference in neutralisation capacity was observed for vaccinated HCWs between the two variants whereas it was not significant for the convalescent groups.”

Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection “Thus, asymptomatic SARS-CoV-2–infected individuals are not characterized by weak antiviral immunity; on the contrary, they mount a highly functional virus-specific cellular immune response.”

Antibody Evolution after SARS-CoV-2 mRNA Vaccination “We conclude that memory antibodies selected over time by natural infection have greater potency and breadth than antibodies elicited by vaccination.”

COVID-19 natural immunity: Scientific Brief. “Available scientific data suggests that in most people immune responses remain robust and protective against reinfection for at least 6-8 months after infection (the longest follow up with strong scientific evidence is currently approximately 8 months)... While neutralizing antibodies mainly target the spike protein, cellular immunity elicited by natural infection also target other viral proteins, which tend to be more conserved across variants than the spike protein.”

SARS-CoV-2 re-infection risk in Austria. “We recorded 40 tentative re-infections in 14 840 COVID-19 survivors of the first wave (0.27%) and 253 581 infections in 8 885 640 individuals of the remaining general population (2.85%) translating into an odds ratio (95% confidence interval) of 0.09 (0.07 to 0.13). We observed a relatively low re-infection rate of SARS-CoV-2 in Austria. Protection against SARS-CoV-2 after natural infection is comparable with the highest available estimates on vaccine efficacies.”

Anti-spike antibody response to natural SARS-CoV-2 infection in the general population “We estimated antibody levels associated with protection against reinfection likely last 1.5-2 years on average, with levels associated with protection from severe infection present for several years.”

SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN). “A previous history of SARS-CoV-2 infection was associated with an 84% lower risk of infection, with median protective effect observed 7 months following primary infection. This time period is the minimum probable effect because seroconversions were not included. This study shows that previous infection with SARS-CoV-2 induces effective immunity to future infections in most individuals.”

SARS-CoV-2 Natural Antibody Response Persists for at Least 12 Months in a Nationwide Study From the Faroe Islands. “Although the protective role of antibodies is currently unknown, our results show that SARS-CoV-2 antibodies persisted at least 12 months after symptom onset and maybe even longer, indicating that COVID-19-convalescent individuals may be protected from reinfection. Our results represent SARS-CoV-2 antibody immunity in nationwide cohorts in a setting with few undetected cases, and we believe that our results add to the understanding of natural immunity and the expected durability of SARS-CoV-2 vaccine immune responses.

Associations of Vaccination and of Prior Infection With Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar. “The relative risk for PCR positivity was 0.22 (95% CI, 0.17-0.28) for vaccinated individuals and 0.26 (95% CI, 0.21-0.34) for individuals with prior infection compared with no record of vaccination or prior infection.”

Longitudinal observation of antibody responses for 14 months after SARS-CoV-2 infection. “In Conclusion, our study findings are consistent with recent studies reporting antibody persistency suggesting that induced SARS-CoV-2 immunity through natural infection, might be very efficacious against re-infection (>90%) and could persist for more than six months. Our study followed up patients up to 14 months demonstrating the presence of anti-S-RBD IgG in 96.8% of recovered COVID-19 subjects.”

46 posted on 10/26/2021 12:52:15 PM PDT by LilFarmer
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To: House Atreides

No one knows for sure where this is headed, but FYI there was a major simulation conducted by Johns Hopkins in 2017 that predicted what would happen if a Corona virus struck the US in 2025. So far, it has read like a script of exactly what is happening now. In a nutshell:

- Government and media caused a wide scale panic over a virus that has a very low likelihood of death

- Experimental vaccines were rushed into production and treatment options withheld

- Social media creates a media blackout and ostracizes anyone who opposes the vaccines

- Ultimately the vaccines prove deadly for millions and the remaining population is left deciding who is mostly to blame and what to do about it

That’s where the simulation was ended, after three years, and probably where we are headed. Read it yourself:

https://www.centerforhealthsecurity.org/our-work/Center-projects/completed-projects/spars-pandemic-scenario.html


47 posted on 10/26/2021 12:56:36 PM PDT by Golden Eagle (Without treasonous Republicans, the Democrats have zero power.)
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To: goldbux

* * * Links to natural-immunity studies * * *


48 posted on 10/27/2021 9:18:29 AM PDT by goldbux (No sufficiently rich interpreted language can represent its own semantics. -- Alfred Tarski, 1936)
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