Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Study finds low rate of COVID-19 "breakthrough" infections, fewer symptoms in vaccinated people
CBS ^ | 01 September 2021 | Tucker Reals

Posted on 09/02/2021 12:36:53 AM PDT by blueplum

London — A study conducted in the U.K. offers some of the first large-scale, real-world data on how well vaccination protects people against catching a "breakthrough" COVID-19 infection, and how well it protects breakthrough patients from becoming seriously ill. The results are encouraging.

The peer-reviewed study published Wednesday in The Lancet medical journal will help policy makers and epidemiologists fill in a significant gap in the understanding of the true efficacy of three of the major vaccines being used worldwide....

The data, gathered from December 8, 2020, through July 4, 2021, show that of more than 1.2 million adults who received a first dose, fewer than 0.5% reported contracting breakthrough infections two weeks or more after getting the jab. Among those who got both shots, fewer than 0.2% experienced a breakthrough infection a week or more after getting their second shot.

"Among those who did experience a breakthrough infection, the odds of that infection being asymptomatic increased by 63% after one vaccine dose and by 94% after the second dose," the study's authors wrote in The Lancet....

(Excerpt) Read more at cbsnews.com ...


TOPICS: Chit/Chat; Dimensional Doorway; Health/Medicine; Science; The Hobbit Hole
KEYWORDS: antivaxtribe; attentionantivaxxers; blueplum; breakthroughs; ccpvirus; coronavirus; covid19; lancet; pandemic; study; thelancet; vaccine; vaccines
Navigation: use the links below to view more comments.
first previous 1-2021-4041-42 next last
To: House Atreides

Small scale real world data this week:

My vaccinated sister-in-law in her mid-50’s with weight comorbidity(and others) has a very mild breakthrough case.

An unvaccinated acquaintance of my wife in his mid-40’s with weight comorbidity died this week.

Would being vaccinated have saved him? Who knows? My guess is yes.


21 posted on 09/02/2021 2:49:22 AM PDT by FreedomForce
[ Post Reply | Private Reply | To 6 | View Replies]

To: dadfly

“the purpose and goal of any vaccine is to prevent infection”

no vaccines give 100% protection against infection

take the MMR vaccine kids get: One dose of MMR vaccine is 93% effective against measles, 78% effective against mumps, and 97% effective against rubella.

Two doses of MMR vaccine are 97% effective against measles and 88% effective against mumps.

another: measles breakthrough in Sweden

https://pubmed.ncbi.nlm.nih.gov/31039835/

the objective of any vaccine is to prevent serious illness and death. Which these vaccines are doing nicely in those without pre-existing and/or age related issues

leaky immune system in that even “natural immunity” is tricked by escape mechanisms developed by the virus. Even healthy immune systems. The virus mutates in the RBD area, the immune system adjusts, but then it mutates in the N-terminal domain where the immune system may not detect or reach. Or an amino acid changes charge from positive to neutral and throws a curve ball.


22 posted on 09/02/2021 2:53:41 AM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
[ Post Reply | Private Reply | To 19 | View Replies]

To: JonPreston

no that is NOT what I’m saying.

I’m saying a person gets two vaccinations, and, then has a MILD breakthrough, as almost all are, they should have the advantage of both vaccine acquired AND wild acquired immune response

IF we accept the study that says the wild acquired infection plus ONE shot afterward, is better, than one SHOT alone, AND better two SHOTS no infection.

What you think I said is infection, 2 shots, infection. That is not what I said


23 posted on 09/02/2021 3:03:38 AM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
[ Post Reply | Private Reply | To 20 | View Replies]

To: blueplum

I call Bull.

Everyone I know who has received a Covid 19 positive diagnosis, including several who have been admitted to the hospital, in the last month are all fully vaccinated.

The idea that “breakthrough cases are rare” is absurd.

Israel which has the 7th highest vaccination rate in !the world had more reported cases of the Kung flu then it has ever reported before.

Unless the UK has some secret sauce no other nation has this is a dubious result at best.


24 posted on 09/02/2021 3:15:17 AM PDT by HamiltonJay
[ Post Reply | Private Reply | To 1 | View Replies]

To: blueplum

Must just be coincidence that everyday famous ball players, musicians, politicians , actors, etc all have breakthrough cases.


25 posted on 09/02/2021 3:15:42 AM PDT by MrRelevant
[ Post Reply | Private Reply | To 1 | View Replies]

To: blueplum
(Your comment) "...a fully vaccinated person being mildly reinfected..."

Do I have to define reinfected for you? Fully vaccinated?

26 posted on 09/02/2021 3:25:04 AM PDT by JonPreston (Q: Never have so many, been so wrong, so often)
[ Post Reply | Private Reply | To 23 | View Replies]

To: bricklayer

I’m referring to the study that was posted a few days ago that the ‘naturally immune’ were crowing over as proof wild immunity was better than vaccines. IF wild immunity is better, than someone who’s had a double vaccination that then gets a breakthrough is, in effect, getting a booster. :

The authors proposed the following regarding Pfitzer vaccines:
natural infection is better than one shot but wanes over time, which is not defined, but
natural infection with one shot is better than no shot, and
natural infection is better than two shots
T-cell and B-cell interactions may contribute more to immunity than antibody-inducing vaccines alone

When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity by May 20, 2021 was demonstrated but not defined in time

Synopsis of the modeling used by the researchers to come to the above conclusions:

Model 1: natural infection vs 2-shot vaccinated: 16,215 persons each group;
257 cases of infection; 238 breakthrough plus 19 reinfections. zero deaths (1.47% vs 0.12%)
199 symptomatic vaccinated; 8 reinfections (1.2% vs 0.06%)
9 hospitalizations: 8 vaccinated; 1 reinfection
13.06-fold increased risk for breakthrough - caveat: “apart from age 60+” no assessed comorbidities affected risk.
27.02-fold increase in risk for symptomtic - caveat: “apart from age 60+” no covariates were significant

Model 2:uninfected 2-shot versus previously infected: 46,035 persons - zero deaths (1.62% vs 0.23%)
748 cases of infection; 640 breakthrough plus 108 reinfections (1.4% vs 0.23%)
552 symptomatic: 484 vaccinated vs 68 reinfection (1.1% vs 0.15%)
25 hospitalizations: 21 breakthrough; 4 reinfection (0.045%)
5.96-fold increase for breakthrough vs - reinfection - caveat: “apart from SES level and age 60+ that remained significant in this model as well”

Model 3a: uninfected versus 1-shot previously infected 14,029 persons = zero deaths (0.11% vs 0.16%)
0.53-fold decreased risk for 1-shot - based on 20 PCR in 1-shot versus 37 PCR on previously infected.
Given: additional protection for preinfected was gained from a single dose
39 symptomatics: 16 1-shot; 23 previously infected (0.11% vs 0.16%)
1 hospitalization: 1 previously infected

Model 3b: previously infected vs 1-shot previously infected
0.68-fold decreased risk for 1-shot


27 posted on 09/02/2021 3:35:01 AM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
[ Post Reply | Private Reply | To 18 | View Replies]

To: blueplum

You aren’t allowed to mention natural immunity! The CDC is still pretending it doesn’t exist.

The published research, OTOH says it is about 80%, which is one of the reasons why severe infection is rare.

But you are right, for the older, at risk crowd a breakthrough infection is the best possible outcome.

It is tragically hilarious that the CDC and vaccine makers and their cheerleaders set themselves up for failure by claiming the vaccines would pretty much eradicate the virus and if you got the vaccine you wouldn’t get sick. Now as it is becoming apparent that was a lie they both claim never to have said that and that there are not many breakthrough infections.

And by consistently lying and raising the bar to a level they can’t possibly ever meet they lurch from failure to failure, from one set of lies to the next, destroying more of their credibility every step of the way. Now even a lot of the vaccinated are coming to the conclusion they were deceived and the pushers are not to be trusted.


28 posted on 09/02/2021 3:40:49 AM PDT by hopespringseternal
[ Post Reply | Private Reply | To 11 | View Replies]

To: blueplum

Read the methodology.

The study is crap.


29 posted on 09/02/2021 3:56:09 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
[ Post Reply | Private Reply | To 1 | View Replies]

To: blueplum

First, we are dealing with tiny numbers of people who have had a breakthrough or reinfection. So in saying that vaccination reduces risk for even the prior infected, I think putting that into the context of there being extremely low risk for either group is helpful. Near zero times .5 is still near zero.

Second, I don’t think we know much yet about the natural immunity conferred on the vaccinated by breakthrough infections. Does any natural immunity result? Is it as good as no-vaccine natural immunity? As far as I know, we have no idea, just speculation.

Third, this whole discussion ignores the adverse effects of the vaccines, established or potential.


30 posted on 09/02/2021 4:51:32 AM PDT by Stingray51 ( )
[ Post Reply | Private Reply | To 27 | View Replies]

To: ransomnote

ransomnote wrote: “You support propaganda, I don’t. You pretend the real world life-saving results being reported world-wide don’t exist. I don’t.”

Oh, but you do support the anti-vaxxer propaganda while you deny the safety and effectiveness of the vaccines.


31 posted on 09/02/2021 5:21:38 AM PDT by DugwayDuke (Most pick the expert who says the things they agree with.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: blueplum

Your “line of reasoning” is devoid of intelligence.

Following your stupidity, why not take 15 vax shots?
You’ll be super duper immune…

Stay away from decision making.


32 posted on 09/02/2021 5:41:21 AM PDT by EEGator
[ Post Reply | Private Reply | To 11 | View Replies]

To: blueplum

This is an interesting point and one that was kicked around on Wharton Moneyball a few weeks ago (granted, by statistical gurus, not scientists).


33 posted on 09/02/2021 5:41:45 AM PDT by Atticus
[ Post Reply | Private Reply | To 11 | View Replies]

To: blueplum

I have 20 employees in my office. We are up to 10 covid infections now, 6 of them were vaxed. 0.2% my a**


34 posted on 09/02/2021 5:43:41 AM PDT by armydoc
[ Post Reply | Private Reply | To 1 | View Replies]

To: ransomnote
Re: But wait...there's more.

Just noticed that every Israeli (188) who died from COVID in August 2021 was at least 50 years old.

Also interesting...

USA population is 35X Israel population.

(Israel August Deaths) 188 X 35 (USA Pop.) = 6,580

For the last four weeks, based on CDC Death Certificates, the COVID August death toll in the USA, adjusted for population, is about 4X higher than Israel.

Big difference.

USA Fully Vaxxed - 53%

Israel Fully Vaxxed - 84.8%

The difference might also be the USA method for choosing cause of death.

If the word COVID appears anywhere on a USA Death Certificate, the Underlying Cause of Death is almost always COVID, no matter what age, no matter what co-morbidities.

35 posted on 09/02/2021 5:46:54 AM PDT by zeestephen
[ Post Reply | Private Reply | To 15 | View Replies]

To: armydoc

Since July 01, the CDC only counts infections for hospitalizations and fatalities.

That makes it impossible to compare data from before July.

The Cleveland Clinic released a study last week that estimated total USA COVID infections at 100 million, including non-symptomatic infections.


36 posted on 09/02/2021 6:01:22 AM PDT by zeestephen
[ Post Reply | Private Reply | To 34 | View Replies]

To: House Atreides
Hmmm…Large-scale, real world data? We don’t need no stinkin’ large-scale, real-world data. Bah-humbug!

Real world data could bash your socialist skull in an you would still swear that Fauci is God.
37 posted on 09/02/2021 6:05:36 AM PDT by Jan_Sobieski (Sanctification)
[ Post Reply | Private Reply | To 6 | View Replies]

To: blueplum; ransomnote
...this thread is about breakthroughs....

Beg to differ:

...how well vaccination protects people against catching a "breakthrough" COVID-19 infection, and how well it protects breakthrough patients from becoming seriously ill.
This thread is about 'vaccine' propaganda.

...often they were bedridden before infection, immobile and already requiring nursing care,”

Well, that explains Provincetown and all the other scareporn pushing these shots upon the healthy and, particularly, almost entirely invulnerable children.

Got it. /s

“...the unvaccinated COVID patients we see are young, healthy, working people and their condition deteriorates rapidly,” she said. “Suddenly they’re being put on oxygen or on a respirator.”
and

"The bad news, doctors say, is that half of Israel's seriously ill patients who are currently hospitalized were fully vaccinated at least five months ago. Most of them are over 60 years old and have comorbidities. The seriously ill patients who are unvaccinated are mostly young, healthy people whose condition deteriorated quickly."
Can't have it both ways, that the 'vaccines' are effective and 'breakthrough infections are rare' (i.e., "low rate") when equally 'rare' are infections among the 'UNvaccinated'.
38 posted on 09/02/2021 6:14:06 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
[ Post Reply | Private Reply | To 17 | View Replies]

To: blueplum

This “study” is in direct conflict with dozens of other peer-reviewed studies. Which one shall we put our faith and trust into today? ... I know ... none. “Science”, particularly medical “science” has devolved into nothing more than “political science”.


39 posted on 09/02/2021 6:18:41 AM PDT by glennaro (Dennis Prager: "Until it's safe" means "Never")
[ Post Reply | Private Reply | To 1 | View Replies]

To: blueplum

“I’m saying a person gets two vaccinations, and, then has a MILD breakthrough, as almost all are, they should have the advantage of both vaccine acquired AND wild acquired immune response”

So should vaccinated people encourage anti-vaxers to remain unvaccinated so the vaxed can more likely catch the mild form of the virus and thus have stronger immunity?

Or even better, should the vaxed be intentionally infected for the same reason?


40 posted on 09/02/2021 6:41:22 AM PDT by aquila48 (Do not let them make you care! Guilting you is how they control you. )
[ Post Reply | Private Reply | To 23 | View Replies]


Navigation: use the links below to view more comments.
first previous 1-2021-4041-42 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson