Posted on 08/29/2021 1:13:46 PM PDT by nickcarraway
Results published in The Lancet have confirmed the benefit of inhaled budesonide in Covid recovery in higher risk patients in the community.
But the Department of Health and Social Care (DHSC) said advice to only prescribe the treatment on a ‘case by case’ basis remains in place for now.
It is understood that NICE are reviewing the evidence from the PRINCIPLE trial, which first published interim results in April.
The Lancet paper confirms that use of budesonide in over 65s or over-50s with high risk conditions who had tested positive for SARS-CoV-2 recovered 2.94 days sooner than those who had usual care.
There is also a ‘chance’ that the drug reduces hospital admissions or deaths with a 2% lower rate in those who were treated but the results did not quite reach the pre-agreed threshold for superiority, the researchers reported.
The final results are in line with those published as an interim paper in April but do not cover other endpoints that had been reported such as patient wellbeing.
Inhaled budesonide was the first treatment to show effectiveness outside the hospital setting.
Recruitment to the budesonide arm in the Oxford University run PRINCIPLE trial was stopped in March after it was agreed that enough patients had been enrolled to assess if the treatment was effective.
Participants were asked to inhale 800 micrograms of budesonide twice a day for 14 days and were followed-up for 28 days.
The initial positive reports prompted the DHSC to advise GPs they could prescribe budesonide on a case-by-case basis but said it was not being recommended for routine use as more evidence was needed before it could be rolled out wider.
Eligible patients must have had onset of Covid-19 confirmed by PCR test within the past 14 days and have ongoing symptoms and be 65 years and over or 50-64 years with a comorbidity consistent with a long-term health condition from the flu list.
A Department of Health and Social Care spokesperson said: ‘These are promising results and we will wait for the experts at NICE to consider any revisions to the clinical guidelines.
‘Until then, clinicians can prescribe this treatment to certain patients on a case-by-case basis, using their individual judgement.’
Click to complete relevant respiratory CPD modules on Pulse Learning.
After hearing one of the docs who will treat early to keep people out of the hospital talk about it, it’s one of the items we have ‘on hand’, just in case.
What has happened to HCQ and Ivermectin as definitive cures with an overwhelming track record??????
I take generic symbicort twice a day. So I guess I am covered.
The Zelenko protocol
Low Risk Patients
Young healthy people do not need prophylaxis against Covid 19.In young and healthy people, this infection causes mild cold-like symptoms. It is advantageous for these patients to be exposed to Covid-19, build up their antibodies and have their immune system clear the virus. This will facilitate the development of herd immunity and help prevent future Covid-19 pandemics. However, if these patients desire prophylaxis against Covid-19, then they should take the protocol noted below.
Moderate Risk Patients
Patients from this category are healthy but have high viral-load exposure. This group includes medical personnel, caregivers of high-risk patients, people who use public transportation or may otherwise be exposed, first responders and other essential personnel who are crucial to the continued functioning of society. These patients should be encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.
High Risk Patients
Patients are considered high risk if they are over the age of 60, or if they are younger than 60 but they have comorbidities, that is, they have other health conditions that put them at risk. These patients have between a 5 to 10% mortality rate if they are infected with Covid-19. These patients should be strongly encouraged to take prophylaxis against Covid-19 in accordance with the protocol noted below.
Protocol for Low and Moderate Risk Patients
Elemental Zinc 25mg one a day Vitamin C 1000mg once a day: (see also)
Quercetin 500mg (OTC) once a day If Quercetin is unavailable, then use Epigallocatechin-gallate (EGCG) 400mg (OTC) once a day: (see also)
Protocol for High Risk Patients
Elemental Zinc 25mg one a day Hydroxychloroquine (HCQ) 200mg once a day for 5 days, then once a week: (see also)
If HCQ is not available, then use Low and Moderate risk protocol
If anything, Budenoside has a more overwhelming track than those. It has all positive results in several different countries.
Don't you find it interesting that you want to do the same thing to Budenoside that the vaccine people did to HCQ and Ivermectin, using the same argument?
Why is that?
Too bad no inclusion of monoclonal antibodies or ivermectin.
I take Symbicort also. Is there a generic form? Symbicort is very expensive.
bkmk
It has become increasingly difficult to get these items.
Kroger pharmacies will no longer honor prescriptions for these medicines if they are for "off-label" use. The same is true for the CVS pharmacies.
I have personally verified these refusals.
Prescriptions from known tele-medicine doctors will not be accepted.
Once can still get Budesonide without questions. This isn't going to last much longer.
The referral procedures to get monoclonal antibodies at an infusion center are a nightmare of catch-22 requirements. Most people will be denied such treatment until it is too late to do any good.
The only way to get such treatment is by referral from a physician who has admitting privileges at the hospital or clinic where they are done. This is probably not your primary care physician, so an additional referral is needed. That also requires a confirmed diagnosis by tests and severity of symptoms. You must be deemed "eligible" for this treatment and sign a bunch of waivers for the "compassionate use" exemption.
Tick-Tock. You have no more than ten days to be eligible, and you have probably burned four of them with paperwork. That is if all goes well.
(Are you reading this "gas_dr".)
There appears to be a massive and coordinated effort to insure that ordinary people cannot obtain effective treatments for COVID-19. The standard prescription to "Go home and take acetaminophen for a week" is not effective treatment.
Bttt
A generic symbicort recently came out. I was surprised when it happened because I think I only paid a $5 co pay instead of something like $40 prior.
It eases difficulty breathing but doesn't attack the virus AFAIK.
I would definitely ask for it, if needed.
I think it calms the virus spread by reducing the immune metabolism. That metabolism is also what attacks and destroys lungs.
In the past 3 weeks, the number of pharmacies who will fill ivermecting has shrunk considerably. Even the horse paste is very difficult to find.
Budesonide will be next to go.
“Vaccines or die!”
Does this apply to the infusion centers in all states that have them?
Or just in certain states?
And do all Kroger’s and CVS’es in all states deny ivermectin prescriptions?
Locations may vary in what they will or won’t do.
Everything you have just described is 100% TRUE! I have witnessed it happen where I live in Central Ga.
Kroger gave me the runaround and get this, tried to tell me they “had my prescription of Olanzapine ready.” Do you know what THAT is? Medicine for schizophrenia! (i do not have schizophrenia) Later when I called back to bitch to the pharmacy manager about that little incident, I could hear her ask the young woman with whom I spoke not 10 minutes earlier. She DENIED speaking to me or telling me that! Kroger is woke.
I hear many of the Walgreens in the area will no longer fill it, but they were filling it 2 weeks ago.
I’ve got some on order from a tele-doc but it has been over a week and the pharmacy, which is supposedly reputable (Honeybee Health), has yet to ship it. So I’m thinking that is not going to end well either.
The pharmaceutical companies control everything. EVERYTHING! DJT pissed them off, so now we are paying for it.
Budenoside is NOT a cure for covid, but as a powerful corticosteroid plumonary anti-inflammatory, it helps to alleviate the pulmonary inflammation caused by covid; nonetheless, that’s a VERY important action in that it can help keep covid from killing you ...
other inhaled aerosol corticosteroids and even corticosteroid suspensions used in nebulizers are likely to be as effective as budenoside ... i personally know one young man who tested positive for covid and utilized zelenko’s triple therapy but also used Flovent HFA (an inhaled aerosol corticosteroid) who said that helped him recover as much as anything else did ...
Could be.
. There are a over 20 medications with studies present. I'm covering only HCQ, Ivermectin, and Zinc.
Medication / %improvment/ relative risk and confidence interval/ number studies/ total patients
Ivermectin.................. 68%... 0.32 [0.25-0.40]... 63... 26,422
Hydroxychloroquine.. 26%... 0.4 [0.69-0.78].... 281.. 407,627
Zinc............................ 51%... 0.49 [0.38-0.64]... 21... 31,199
Zinc and NCQ are on the list. I don't know if anyone has actually given the Zelenko Protocol a proper clinical trial.
The current Zelenko protocol is Querctin, Zinc, Vitamin A and D3 since they are all over the counter.
It is also really hard for the mainstream news to stigmatize over the counter drugs.
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