Posted on 08/26/2021 9:50:06 AM PDT by BenLurkin
Sotrovimab, the newest antibody therapy, was developed by GlaxoSmithKline and Vir Biotechnology after a large collaborative study by scientists from across the nation discovered a natural antibody (in the blood of a SARS survivor, back in 2003) that has remarkable breadth and efficacy.
Experiments showed that this antibody, called S309, neutralizes all known SARS-CoV-2 strains – including newly emerged mutants that can now “escape” from previous antibody therapies – as well as the closely related original SARS-CoV virus.
Jay Nix, leader of the Molecular Biology Consortium based at Berkeley Lab’s Advanced Light Source (ALS), used beamlines at the ALS and beamlines at SLAC’s Stanford Synchrotron Radiation Lightsource to perform X-ray crystallography on samples of survivor-derived antibodies during an early phase of the study. His work, alongside other crystallography and cryo-electron microscopy findings, helped generate detailed structural maps of how these antibodies bind to the SARS-CoV-2 spike protein, allowing the wider team to select the most promising contenders and advance them to cell culture- and animal-based studies. Following exciting lab results, the developers designed sotrovimab based on the structure of S309, and evaluated it in clinical trials.
The FDA granted an EUA for sotrovimab in late May after trials showed that people with mild to moderate COVID-19 infections who received an infusion of the therapy had an 85% reduction in rates of hospitalization or death, compared with placebo.
(Excerpt) Read more at scitechdaily.com ...
thx aimhigh.
Ah, I was under impression it was for mid to late stage, in hopes of keeping them off breathing tubes. Thanks for the clarification
That’s a very important point!
Wish I had thought to make it...
I do not have any covid symptoms but I am considering going
for infusion as a prophylactic measure.
I’m fat and retired so I should get it...
Not really
Hopeful mark.
AND. IT FREE !
Where do I get my free silver?
Hopefully this treatment will achieve widespread use if it is as good as this article claims.
—
Effective treatments for active cases makes far more sense than vaccinating every man, woman, child, cat, dog, and whitetail deer with vaccines of questionable efficacy and a very real potential of harm.
“The Death Gnome will not be happy ... unless he can find a way to get his fingers in the $$ pie.”
The going rate is 10% for The Big Guy.
Everyone else gets crumbs. Ask Humper.
Fauxi just wants to continue his tv face time.
And probably because they actually work.
There’s no money to be made by big pharma if people get well.
Take one of your sterling silver forks and file or sand it then gently breathe the dust
The National Institute of Health confirms that colloidal silver can kill viruses like COVID:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486059/
But there are considerations such as cytotoxicity which means that you can have too much of a good thing. Colloidal silver can kill good gut bacteria which are important for our health. Also, evidence suggests that silver particles in the 10 nm size are optimized for the therapeutic benefits, but many self-made or over-the-counter solutions could contain particles that are ineffective due to their size.
LOL! Me too!
They merely take bamivortos and spell it backwards.
Yeh what the hell! The chinks get us on one side, and the Roosians from the other! What could possibly go wrong!
It Sounds Great — but — for a disease with a 99.97+% recovery rate, probably unnecessary.
anagram
👍
from the shrinking pool of available domain names...lol
I would have named it “my covid blaster”
Since fully half of studies end up being complete fraud I’ll withhold judgement.
Most “miracle “ drugs end up being pulled from the market.
This is the therapy that Trump and Giuliani got. Governor DeSantis has pushed to open clinics to help people get access to this treatment in Florida.
It works even with mutations of the virus for up to a year, and the safety profile is excellent.
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