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(STUDY) Why so many vaccinated people are getting sick: Antibody Dependent Enhancement (ADE)
SharylAttkisson.com ^ | August 16, 2021 | Sharyl Attkisson

Posted on 08/16/2021 12:31:42 PM PDT by Qiviut

According to studies:

ADE can make vaccinated people more susceptible to serious infection from the virus "ADE may be a concern" for those who have been vaccinated for Covid-19 With ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in "increased viral replication and more severe disease, leading to major safety risks" ADE can also "occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don't protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness" This concern was initially described by some scientists who were subsequently banned from media platforms that incorrectly claimed the scientists were disseminating disinformation Study scientists suggest the answer is to create a new vaccine

In a new study in the Journal of Infection, scientists explain one likely reason why so many vaccinated people are getting sick: a dangerous phenomenon called Antibody Dependent Enhancement or ADE.

Despite the fact that multiple medical authorities predicted, told us, and hoped, ADE would not impact Covid-19 vaccines, data from the study indicates it has done just that.

According to the new study, data suggests that the Covid-19 vaccines originally appeared to provide an overall benefit in fighting the virus. However, when it comes to one of the newer iterations of Covid, the Delta variant, the vaccines appear to facilitate infection displaying "a strikingly increased affinity" for the virus' trademark spike protein.

The scientists conclude that "ADE may be a concern" for those who have been vaccinated for Covid-19.

Read the study here [see live link at source].

According to scientific study, the ADE risk was well known prior to the Covid-19 vaccines being allowed on the market.

"One potential hurdle for antibody-based vaccines and therapeutics is the risk of exacerbating COVID-19 severity via antibody-dependent enhancement (ADE)," explained a study in Nature. "ADE can increase the severity of multiple viral infections, including other respiratory viruses such as respiratory syncytial virus (RSV) and measles."

Scientists say that with ADE, after people get vaccinated for an initial virus, infection by a subsequent variant or strain of the virus can result in "increased viral replication and more severe disease, leading to major safety risks."

"Non-neutralizing antibodies generated by past infection or vaccination fail to shut down the pathogen upon re-exposure. Instead, they act as a gateway by allowing the virus to gain entry and replicate in cells that are usually off limits... That, in turn, can lead to wider dissemination of illness, and over-reactive immune responses that cause more severe illness," according to scientists.

An article in MedPage (prior to the new study) dismissed concerns about ADE, but noted it "can also occur when neutralizing antibodies (which bind the virus and stop it from causing infection) are present at low enough levels that they don't protect against infection. Instead, they can form immune complexes with viral particles, which in turn leads to worse illness."

On the other hand, most scientific studies on this topic say those who have recovered from Covid-19 have natural immunity that does not display the same problem, and appears to be superior to that, so far, of that provided by the vaccines.

Nonetheless, the Centers for Disease Control (CDC) and many public health officials are pressing for more people to get vaccinated, including those who have been previously-infected with Covid. (Numerous studies suggest there is no benefit to recovered patients getting vaccinated.) The health officials state that the vaccinated patients who are getting Covid are getting milder forms than they would have if they had not been vaccinated. However, that is a case-by-case assumption and is impossible to prove.

In Israel, health officials say that only 1% among Covid infections in the latest wave are among those previously infected with Covid. The other 99% are among unvaccinated and not previously-infected, and among fully-vaccinated.

According to the new study, the solution to the current ADE problem is to invent a new, updated version of the vaccine.

Read more from the new study below [at the link]:


TOPICS: Health/Medicine
KEYWORDS: ade; antivaxbs; antivaxhysteria; antivaxxerfantasy; attkisson; chinavirus; chinavirusvaccine; covid19; dumbingdownfr; fake; fearmongering; fearporn; vaxfear
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To: Qiviut

And they named it the delta variant just to keep the fear narrative going.


41 posted on 08/16/2021 3:04:12 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith…. )
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To: Qiviut

that’s a good question -

I checked his wiki page and it says after he tested positive the first time, he tested negative and he was taking tests before Tokyo, which is no help.

The SUN uk says that after that first positive he tested negative and competed in a tourny a few weeks later. Then sometime between June 20 tourney and July 25 announcement, he got vaccinated. Which would have put him outside the ‘second shot plus 2 weeks’ window for best protection. I don’t know if he was infected with Delta both times, had a false positive, or if one was Alpha and one Delta. It is possible to get infected with Delta after recovering from Alpha just because Delta is a stronger virus.

But it must have been a mild infection because he played ‘top ten’ in the Scottish Open Rolex series Jul 10, a ‘near picture-perfect’ round on July 19 in England, and won the 2021 US Open on Aug 1.


42 posted on 08/16/2021 3:05:34 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: 2aProtectsTheRest

You guys won’t find what you don’t want to find.

Admitting ADE to the public would kill the cash cow you are foisting on the American public and want to mandate for everyone.


43 posted on 08/16/2021 3:06:16 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith…. )
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To: blueplum

Don’t forget that Elon Musk got tested four times in one sitting and two came back positive and two came back negative.

Real reliable test there.


44 posted on 08/16/2021 3:10:34 PM PDT by metmom (...fixing our eyes on Jesus, the Author and Perfecter of our faith…. )
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To: 2aProtectsTheRest

I am not sure on the the ones who are not having a good trial, but the rest are at home.

One was in his garden, and complaining that he was sneezing.

I am still giving plasma, and the Vampire Nurses (my name for them) have said they are very picky about who gets the antibodies.


45 posted on 08/16/2021 4:02:50 PM PDT by redgolum (If this is civilization, I will be the barbarian. )
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To: Ceebass

” ADE could be the reason why the vaccinated are being infected by the delta variant”

It could be, and I sure hope we don’t see it. It could be because delta sugar-coated itself to fool the immune system, too, tricky little bugger. If we start seeing breakthroughs in younger age groups that require hospitalization, then it’s time to sweat.

The current ‘confirmed cases’ (ever infected) in the US is pretty much 10% of the pop. Otoh, there’s a 1 in 1,300 risk of a breakthrough infection, averaged across ages, and the number of breakthroughs requiring hospitalization is very small:

NBC news reported that only 10K of of 125K breakthroughs required hospitalization, or 0.08% of 0.08%:
“ According to NBC “ 125,682 “breakthrough” cases in 38 states found by NBC News represented less than 0.08% of the 164.2 million-plus people (and counting) who have been fully vaccinated since the start of the year, or about one in every 1,300.”

Mass reports 100 total breakthrough deaths, average age 82, as of July 30, amounting to 0.002% of the total vaccinated in that state.

According to the Minnesota Dept of Health (also Oregon and Mass) “the median age of breakthrough cases that have resulted in hospitalization is 74.” So the same immune compromised population challenged with a stronger virus.

Fox reports CDC reported on July 26 “Out of the 6,587 cases, 1,263 vaccinated people died “ speaking of hospitalized cases. Again, in contrast to 160M vaccinated.

https://www.nbcnews.com/health/health-news/rarely-covid-vaccine-breakthrough-infections-can-be-severe-who-s-n1274164
https://www.cnbc.com/2021/08/10/breakthrough-covid-cases-why-fully-vaccinated-people-can-get-covid.html
https://www.fox5dc.com/news/cdc-less-than-1-of-breakthrough-covid-19-cases-led-to-hospitalization-or-death
https://www.msn.com/en-us/news/us/as-of-july-31-mass-reports-100-breakthrough-covid-19-case-deaths-0002-percent-of-all-fully-vaccinated-people/ar-AAN7IPZ?ocid=uxbndlbing


46 posted on 08/16/2021 4:25:16 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: metmom

I remember that, and remember wondering, was that before or after he packed his nose with coke? :) kidding tho

the CDC screwed up royal - They should never be able to live down not being able to get regeants and mailing labels right and doing whatever they could to throw monkey wrenches into Operation Warp Speed.


47 posted on 08/16/2021 4:29:28 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: blueplum

How is the sugar coating of the Delta variant different from the sugar coating this coronavirus had always had?


48 posted on 08/16/2021 5:17:56 PM PDT by FreedomForce
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To: FreedomForce

I can only guess from the little I’ve read, but there’s a D614G mutation, which “increases the density’ of the spike (which, I’m also guessing, would make the sugar layer more dense and cover more of the ‘blank’ spots or ‘holes’ in the coating) And then in there somewhere is the S13T and L452R mutations contributing to the increased shielding. But it’s just a guess.

Cool pix of sugar coat with ‘holes’:
https://www.kpbs.org/news/2020/jun/25/coronavirus-covered-sugar-shield-uc-san-diego-scie/


49 posted on 08/16/2021 5:52:55 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: metmom

No, Elon Musk got two rapid antigen tests which are unreliable and one RT-PCR test. The RT-PCR test was positive, as Elon Musk stated he thought it would be, since he had symptoms consistent with COVID-19.


50 posted on 08/17/2021 4:26:02 AM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: metmom
"You guys won’t find what you don’t want to find."

No, I won't find what doesn't exist because I don't live in a fantasy world. If evidence of ADE presents itself, I'll absolutely point to it. But evidence of ADE would be a shift to increased adverse outcomes for those previously infected and/or vaccinated versus those with no prior vaccination or infection. That hasn't happened. Anywhere. Those who have been vaccinated show much better outcomes than those never vaccinated or infected. Those who become reinfected also show better outcomes than controls.

So no, there is no evidence of ADE. From what I can tell, just a lot of disturbingly wishful thinking from people who have no idea what ADE even is. They just really seem to want people who've been vaccinated to have bad outcomes. It isn't happening, thankfully, and it's disgusting that some would desire hundreds of millions of people to have bad outcomes just so their worldview about vaccines can be justified.

51 posted on 08/17/2021 4:31:05 AM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: redgolum

Important to note that monoclonal antibody therapy is significantly different from convalescent plasma. Two completely different treatments with different outcomes. Monoclonals are available at infusion centers around the US and are proven to work. They worked for President Trump, they can work for you if you’re sick.


52 posted on 08/17/2021 4:32:58 AM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: Qiviut
Antibody-Dependent Enhancement Risk for SARS-CoV-2 Vaccine Developers

“Because if the gun is jumped, and a vaccine is widely distributed that is disease enhancing, that would be worse than actually not doing any vaccination at all.”

53 posted on 08/17/2021 4:40:11 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: 2aProtectsTheRest
Interesting link...

Viral-Induced Enhanced Disease Illness

54 posted on 08/17/2021 4:42:23 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: mewzilla

Which is exactly what they’ve done, IMO.


55 posted on 08/17/2021 4:43:41 AM PDT by Qiviut (Faith is the antidote to fear. Mindset: be a victor, not a victim.)
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To: 2aProtectsTheRest
One more...

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies

56 posted on 08/17/2021 4:43:47 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: Qiviut

I agree.


57 posted on 08/17/2021 4:44:03 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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To: mewzilla

Your own link contains zero evidence of any ADE happening with COVID-19. From your own link:

“The extent to which ADE contributes to COVID-19 immunopathology is being actively investigated.”

In other words, “we’re still looking for it”. Over 208,000,000 worldwide over the past 20+ months and “still looking for it”? Huh. We didn’t have to look long to see it happening with Dengue virus. Or HIV-1. Or Zika. Or Yellow Fever. Or RSV.

But man, that SARS-CoV-2, 200 million cases, still can’t find a shred of evidence it’s happening, but NO DOUBT we’ll see it ANY TIME NOW.

No doubt. /s


58 posted on 08/17/2021 4:54:29 AM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: Qiviut

Where is the evidence that vaccinated people are having worse outcomes than unvaccinated?

99% of the people dying from COVID-19 are unvaccinated. Over 90% of the people hospitalized for COVID-19 are unvaccinated. Meanwhile, 81% of seniors in the US are fully vaccinated. Since they’re most of the hospitalizations and deaths, if the vaccines were neutral (no benefit or harm), we should see roughly 81% of the hospitalizations and deaths happening with vaccinated people. But we don’t. If the vaccines caused worse outcomes, nearly all the hospitalizations and deaths should be with vaccinated people. They aren’t.

The exact opposite of what’s claimed here is happening in the real world. In every single state, it’s the same story. Texas, Florida, Georgia, Kentucky, Indiana, Maryland, Virginia; all seeing the same outcome: nearly all the people with severe COVID-19 are unvaccinated.


59 posted on 08/17/2021 4:58:27 AM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: 2aProtectsTheRest
They've seen it in animal studies...

Dissecting strategies to tune the therapeutic potential of SARS-CoV-2–specific monoclonal antibody CR3022

Holy crap, maybe even with convalescent plasma...

The potential for antibody-dependent enhancement of SARS-CoV-2 infection: Translational implications for vaccine development

60 posted on 08/17/2021 5:11:52 AM PDT by mewzilla (Those aren't masks. They're muzzles. )
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