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medpagetoday.com
medpagetoday.com ^ | July 28, 2020 | Molly Walker

Posted on 04/24/2021 3:33:34 PM PDT by ransomnote

ransomnote: I'm frequently told that the Moderna Vaccines proved safe and effective in animal trials with monkeys. I'll explain why that's not true in post #1. Here's an article providing a description of the research.


The mRNA vaccine co-developed by Moderna and the National Institute of Allergy and Infectious Diseases (NIAID) protected both the upper and lower airways of non-human primates against SARS-CoV-2 infection.

Rhesus macaques receiving low or high doses of mRNA-1273 vaccine (10 or 100 μg, two injections 4 weeks apart) were then challenged with the virus via both the nose and the lungs a month after the second injection. Seven of eight vaccinated monkeys in both dosing groups had no detectable virus in the lungs two days afterwards, whereas viral RNA was found in lungs of all eight monkeys receiving placebo, according to Barney Graham, MD, PhD, of NIAID, and colleagues.

And all monkeys receiving the higher dose of vaccine had no detectable virus in their noses two days after the nasal challenge, compared with three of eight in the low-dose group and two of eight receiving placebo, Graham's group reported in the New England Journal of Medicine.

"A COVID-19 vaccine that reduces viral replication in the lungs would limit disease in the individual, while reducing shedding in the upper airway would potentially lessen transmission of SARS-CoV-2 and consequently reduce the spread of disease," the NIAID said in a statement.

MORE AT THE LINK


TOPICS: Miscellaneous
KEYWORDS: chinavirusvaccine; info; moderna; mrna
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mRNA 'vaccines' a terrible experimental history in which they never made it past animal trials until Covid-19. In prior mRNA research 2005 and 2012, all cats injected with a platform mRNA 'vaccine' developed antibodies. When exposed to the virus, all cats died. The ability to trigger anti-body production is not sufficient to calls something a 'vaccine' since pathogens also trigger that response.

mRNA never succeeded as HIV, Hep C or other Corona virus vaccines. That's why the mRNA technology has never been FDA approved; it failed.

There have been mRNA mouse studies - they exposed the mice to SARS-1 and then sacrificed (killed) the mice to examine their lungs. Despite 'vaccination', the mice had infected lungs.

SO these 'monkey' trials are cited as proof that the experimental Covid-19 'vaccine'   is finally proving mRNA technology is safe for humans and works to protect against Covid-19. There's just so much wrong with this assertion, where to begin....

8 Rhesus macaques were given a high dose of the 'vaccine' and 8 were given a low dose of the 'vaccine'. The vaccine developers chose one of the dose levels to move forward with, meaning 8 macaques are standing in for the safety of the entire world's popuation if they used the same dose on humans, but why would they? So the macqaque study is irrelevant and all involved knew it.

8 subjects of any speciies is statistically inadquate sampling. Even if that had been tried on 8 unfortunate humans at each dose, and then used that dose on people, humans have too many variations in their response to drugs/'vaccines' etc. to make any claim that '8 is enough.'  

Further, Covid-19 is not available as an isolated sample  (also here and here) which would be required to test exposure to it, right? They used a slurry they 'think' has Covid-19 in it but they don't know as theirs contains a mixture which is likely one or more straings of  influenza and a variety of other materials.

Moreover, the 'test' for Covid-19 does not detect the presence of what researchers claim is the Covid-19 virus (see same 3 links in above paragraph). So it's unknown whether or not the animals had or did not have what the researchers claim is Covid-19 because they weren't testing for it. They could observe symptoms of influenza or other, but wouldn't know what it was. They could have tested for the flu, but given theirs is not mere incompetence, but is instead the weaponization of science against the public, I don't believe they would.

So the macaques were exposed to some version or other of Corona virus or maybe none at all. It turns out rhesus macacques never really become severely ill from SARS-1; their symptoms are mild and they recover completely. That's why they chose this type of primate. If SARS-1 was present in their slurry, it may be that 2 days is not long enough for the animals to display symptoms.

So you have researchers using a fake PCR 'test' and an unidentified slurry they claim, but can't prove, conatains at least 'some' Covid-19 - do you see the problem here. They are lying. The vaccines are China's biowarfare so I'm not surprised they claim their tiny little sample of macaques did well for TWO WHOLE DAYS following infection! That's right! When known adverse effects usually settle in at the 3 to 6 month mark, the Moderna team tested the macaques 2 days after exposure to the sludge sample and declared it a success.

For more about the inadequate trials for the mRNA's now being Phase III tested on the world, click the link:

ADVERSE EFFECTS OF MESSENGER RNA VACCINES An Evidence Review from the Penn Medicine Center for Evidence-based Practice


1 posted on 04/24/2021 3:33:34 PM PDT by ransomnote
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To: ransomnote; admin

Dear Admin, I accidentally posted a date instead of the title for this article, which is:

Monkey Data Support Moderna COVID-19 Vaccine
— Prevents disease, perhaps transmission too in preclinical tests

If possible, could you update the title? I apologize for the error.


2 posted on 04/24/2021 3:35:11 PM PDT by ransomnote (IN GOD WE TRUST)
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To: ransomnote

So they use animals to test it? Why is there no uproar from PETA?


3 posted on 04/24/2021 3:38:50 PM PDT by Mercat
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To: ransomnote

“ransomnote: I’m frequently told that the Moderna Vaccines proved safe and effective in animal trials...”

1). There are no trials in animals. There are only trials with humans.

2) there is no safety determined in animals. Safety is only determined in clinical trials.

Animal studies are pre-clinical research or studies. Safety is not determined but toxicity is assessed which provides information for designing the human safety trials.


4 posted on 04/24/2021 3:42:23 PM PDT by ifinnegan ( Democrats kill babies and harvest their organs to sell)
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To: ransomnote

Well, so much for the canard that the mRNA vaccines were never tested in animals.


5 posted on 04/24/2021 3:46:13 PM PDT by House Atreides (mil)
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To: House Atreides
Well, so much for the canard that the mRNA vaccines were never tested in animals.

~~~~~~~~~~~~
The assertion was that they were never successfully tested in animals.

All the cats in trials 2005 and 2012 died when their immune systems over-heated as a result of 'vaccination.'

The mice trials proved that the mice became ill (infected lungs Sars-1). The rhesus macqaues were not known to be exposed to Covid-19 as no isolated samples exist and as they are relatively resistant (never become severely ill) to Sars-1. 

The animal trials failed or were shams. No successful animal trials for mRNA 'vaccines' exist.

6 posted on 04/24/2021 3:56:22 PM PDT by ransomnote (IN GOD WE TRUST)
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To: ransomnote
Many many prototype vaccines fail in animal testing and never make it to human testing. This really is no big deal. This particular study assessed vaccine efficacy in monkeys. Before that, no doubt, countless rodents were given the vaccine and their immune responses assessed. No one ever takes prototypes synthesized in the lab and proceeds directly to testing in monkeys, since monkeys are expensive and the animal welfare laws for handling of monkeys are very strict. They test in cell culture, then in small animals. By the time they are ready to test in non-human primates, they already have volumes of data on the prototype's effects and can anticipate the results in monkeys.

And in every case, the Covid-19 vaccines were tested in humans during clinical trials.

What is your interest in trying to scare people about vaccines, anyway? Do you share the belief that fighting infectious disease caused human overpopulation? Do you share the anti-vaxxers goals to scare enough people away from vaccines that infectious disease will once again kill half or more of all people, thereby "solving" the problem of overpopulation?

7 posted on 04/24/2021 3:59:42 PM PDT by exDemMom (Current visual of the hole the US continues to dig itself into: http://www.usdebtclock.org)
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To: ransomnote

So the testing with rhesus macaques determined that the COVID-19 vaccines were not toxic prior to advancing to human trials. MISSION ACCOMPLISHED!


8 posted on 04/24/2021 4:00:40 PM PDT by House Atreides (mil)
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To: House Atreides

And the flat earthers now reach for the associated editor of a website with little of any clinical background

It appears there is desperation ....


9 posted on 04/24/2021 4:04:16 PM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: exDemMom
Many many prototype vaccines fail in animal testing and never make it to human testing.

This isn't The Island of Dr. Moreau. They are making fake vaccinations a social respsonsibility, injecting our medical staff and first responders with experimental technology with a track record of failure, they are injecting kids as young as 12 years old and pregnant women. I HAVE A CONSCIENCE and can't stay silent.

This really is no big deal.

If you don't care about humanity, it's no big deal. But I do care.

This particular study assessed vaccine efficacy in monkeys. Before that, no doubt, countless rodents were given the vaccine and their immune responses assessed. No one ever takes prototypes synthesized in the lab and proceeds directly to testing in monkeys, since monkeys are expensive and the animal welfare laws for handling of monkeys are very strict. They test in cell culture, then in small animals. By the time they are ready to test in non-human primates, they already have volumes of data on the prototype's effects and can anticipate the results in monkeys.

You don't fail in animal testing, choose a sample of 8 animals that are resistant and test them before they have time to incubate, become ill and then declare everyone in the world MUST get this dangerous vaccine STAT before they find out what the real side effects are. There is no need for vaccination as Covid-19, or whatever illnesses they are calling Covid, has a survivability rate of 99.8 or so percent IF YOU DENY ALL TREATMENT to the ill. If the ill were treated, the rate of death would be tiny. 

And in every case, the Covid-19 vaccines were tested in humans during clinical trials.

I've already demonstrated that no double-blind, phase III large scale testing has done on humans. mRNA failed and was dangerous/lethal so they made it a requirement for airline travel, employment etc.

What is your interest in trying to scare people about vaccines, anyway?

China is behind the vaccines and is orchestrating the lack of proper response to it. I don't want to be a Chinese slave, which they don't want either as I'm too old. But if you want the US to passively enter medical slavery and sicken and die from unnecessary vaccinse, you're doing a good job of supporting it.

Do you share the belief that fighting infectious disease caused human overpopulation? Do you share the anti-vaxxers goals to scare enough people away from vaccines that infectious disease will once again kill half or more of all people, thereby "solving" the problem of overpopulation?

No, but you do. The 'vax' is the biowarfare agent deployed against the world.

10 posted on 04/24/2021 4:08:34 PM PDT by ransomnote (IN GOD WE TRUST)
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To: House Atreides

So the testing with rhesus macaques determined that the COVID-19 vaccines were not toxic prior to advancing to human trials. MISSION ACCOMPLISHED!

~~~~~~~~~~~
They only tested 8.
The animals are not susceptible to the broth of mixted viruses, some of them likely corona
They didn’t wait around longer than 2 days to see if the animals sickened and died.
For your side, pawning this sham off as ‘safety testing’ is mission accomplished in the goal of forwarding China’s biowarfare vaccines to the public.


11 posted on 04/24/2021 4:11:37 PM PDT by ransomnote (IN GOD WE TRUST)
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To: ransomnote

So you believe every American scientist...every American physician and every American person associated with operation warp speed which was the creation of PDJT is either in on the grand conspiracy OR too stupid to know the difference?

That’s an awfully tall bar to clear my friend.


12 posted on 04/24/2021 4:14:23 PM PDT by gas_dr (Trial lawyers AND POLITICIANS are Endangering Every Patient in America: INCLUDING THEIR LIBERTIES)
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To: exDemMom
This is what some of us are worried about:

The West's Obituary.

13 posted on 04/24/2021 4:23:28 PM PDT by DuncanWaring (The Lord uses the good ones; the bad ones use the Lord.)
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To: House Atreides

How dare you point out the facts that prove what you’ve been saying from a anti-vaccine article!

How much is Bill Gates paying you???


14 posted on 04/24/2021 4:24:34 PM PDT by David Chase
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To: ransomnote

Ping.


15 posted on 04/24/2021 4:24:44 PM PDT by DuncanWaring (The Lord uses the good ones; the bad ones use the Lord.)
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To: ifinnegan

You can’t possibly know more than ransomnote :-)


16 posted on 04/24/2021 4:28:02 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: House Atreides

No it said 8 monkeys survived (if we can believe any claptrap a drug company puts out). Many humans have not.


17 posted on 04/24/2021 4:45:57 PM PDT by dforest (huh?)
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To: ransomnote

https://www.thehealthyamerican.org/religious-exemption-card

18 posted on 04/24/2021 4:52:40 PM PDT by Pollard
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To: gas_dr
There's always going to be desperation when you're trying to convince people that observable reality isn't real.


19 posted on 04/24/2021 4:57:06 PM PDT by 2aProtectsTheRest (The media is banging the fear drum enough. Don't help them do it.)
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To: gas_dr

You mean the author who has a BS in Advertising (i.e. a BS in BS) and whose credentials include interviewing Dr. Fauci, should not be believed without question?

I’ll say this: People’s attitudes about the vaccines are fixed, I’ve yet to read anything in any of these seemingly endless diatribes against the vaccines where someone says they’ve changed their mind. If their goal is just to rattle around in their echo chamber, fine, but none of this is persuasive, no minds are being changed.

And people will continue to get vaccinated - or not - as they choose. It’s hard to prove bias in the MSM when the alternative media commits the same sins.


20 posted on 04/24/2021 5:34:02 PM PDT by bigbob
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