“ransomnote: I’m frequently told that the Moderna Vaccines proved safe and effective in animal trials...”
1). There are no trials in animals. There are only trials with humans.
2) there is no safety determined in animals. Safety is only determined in clinical trials.
Animal studies are pre-clinical research or studies. Safety is not determined but toxicity is assessed which provides information for designing the human safety trials.
You can’t possibly know more than ransomnote :-)