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Dogs Can Sniff Out Lethal Prostate Cancer With High Accuracy, Suggests First Blind Study
IFLSCIENCE ^ | 24 FEB 2021 | Jack Dunhill

Posted on 02/24/2021 5:01:54 PM PST by nickcarraway

If you own a dog, you already know they are masters of sniffing rears. Despite wielding powerful noses that can detect diabetes and even COVID-19, they often prioritize diving into the nearest posterior to make friends as opposed to putting them to good use, but you can’t stop them doing what they love.

Steering them in the right direction, researchers from Medical Detection Dogs have concluded a trial for scent dogs detecting the presence of prostate cancer and found they are highly sensitive to the most aggressive forms of the disease. The study, which is published in the journal PLOS ONE, aimed at assessing two dogs’ ability to detect lethal prostate cancer in urine samples. Florin and Midas, the genius sniffer dogs, were capable of identifying urine samples from patients with prostate cancer with high specificity, giving hope for a non-invasive cancer diagnostic test that can support the current blood tests.

The researchers even suggest that the dog’s incredible noses could be replicated in a synthetic device in the future.

“This is hugely exciting because one of the challenges of the PSA blood test, the test most widely used at the moment, is that other conditions can cause an elevated PSA but that does not necessarily mean you have cancer. The dogs in this study were able to differentiate between cancer and other prostatic diseases with good reliability,” said Dr Claire Guest, Medical Detection Dogs’ co-founder, in a statement.

“This additional information could support the PSA and would provide earlier, non-invasive, sensitive detection of clinically aggressive prostate cancers that would most benefit from early diagnosis, simply from a urine sample.  This has enormous potential and in time the ability of the dogs’ nose could be translated to an electronic device.”

Prostate cancer is the second leading cause of lethal cancers in American men, with 1 in 8 men being diagnosed in their lifetime. Current diagnostic tests, such as prostate-specific antigen (PSA) screening, can be unreliable, with many giving false-positive results leading to treatments that aren’t necessary.

Dogs have proven to be accurate at identifying various cancers, but this is the first double-blind study (meaning neither researchers nor dogs knew where the positive samples were) to stop trainers subconsciously biasing the dogs. After being given a carousel of samples to sniff and choose from, the dogs accurately identified samples from cancer patients 71 percent of the time and ignored samples from other patients 73 percent of the time. These are marked improvements over the 21-51 percent sensitivity of current PSA screening, suggesting that while the dogs are not practical for an accurate single test, usage alongside other methods could save countless lives.

Check out Florin being the good boy he is in the video below.

With the knowledge that dogs can detect molecules in the odor of cancer samples, the researchers are now attempting to pin down what it is they are smelling to create an artificial nose. These could be far more scalable for widespread testing, be made more accurate, and free up the dogs to play more fetch.


TOPICS: Health/Medicine; Pets/Animals; Science
KEYWORDS: cancer; dogs; prostatecancer
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1 posted on 02/24/2021 5:01:54 PM PST by nickcarraway
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To: nickcarraway

My crotch sniffing Lab would be a pefect candidate.


2 posted on 02/24/2021 5:05:10 PM PST by Wilderness Conservative (Nature is the ultimate conservative)
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To: nickcarraway

bookmark


3 posted on 02/24/2021 5:08:59 PM PST by GOP Poet (Super cool you can change your tag line EVERYTIME you post!! :D. (Small things make me happy))
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To: Wilderness Conservative

That was my first thought, they stick their nose there so often they are bound to detect when something is wrong.


4 posted on 02/24/2021 5:09:35 PM PST by LukeL
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To: Wilderness Conservative

My chihuahua would need a ladder.


5 posted on 02/24/2021 5:16:29 PM PST by oldasrocks
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To: nickcarraway

Now I know why my Greyhound Ginger’s nose was in my crotch!
“ the researchers are now attempting to pin down what it is they are smelling to create an artificial nose.”


The senses of smell and taste, which we humans aren’t that great at, is one sense that we haven’t yet greatly improved with mechanical/electrical devices. Vision has had the telescope and microscope for centuries and we’ve extended our sense of sound to detect very faint sounds in frequencies we cannot hear.

But we have no idea what the world reveals to our pups when they are busy sniffing the ground.


6 posted on 02/24/2021 5:18:34 PM PST by hanamizu
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To: nickcarraway

Beware, cold nose!


7 posted on 02/24/2021 5:21:59 PM PST by a fool in paradise (Lean on Joe Biden to follow Donald Trump's example and donate his annual salary to charity. )
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To: a fool in paradise

I’ve got a queer buddy that will stick his finger up there for free. if there’s anything up there he’ll find it.


8 posted on 02/24/2021 5:42:45 PM PST by DIRTYSECRET (`)
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My dog smells like a dog.


9 posted on 02/24/2021 5:46:25 PM PST by sonova (That's what I always say sometimes.)
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To: DIRTYSECRET

10 posted on 02/24/2021 5:58:53 PM PST by billorites (freepo ergo sum)
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To: hanamizu

One of my dogs used to ride in the car with his nose to the vent on the dashboard. If we got within 50 feet of a dog, he’d stand up and check it out.


11 posted on 02/24/2021 6:12:47 PM PST by gundog (It was a bright cold day in April, and the clocks were striking thirteen. )
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To: billorites

12 posted on 02/24/2021 6:14:38 PM PST by BenLurkin (The above is not a statement of fact. It is either opinion, or satire. Or both.)
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To: nickcarraway

They blinded the dogs!?!? How CRUEL!!!


13 posted on 02/24/2021 6:49:25 PM PST by OrangeHoof (Halftime score: COVID-19, Constitutional Freedoms - 0)
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To: nickcarraway

Can POTUS sniff out prostate cancer or just young girls?


14 posted on 02/24/2021 7:24:29 PM PST by packagingguy
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To: nickcarraway

That would have been far more preferable than that damned biopsy regime. 12 samples? Seriously?


15 posted on 02/24/2021 7:29:54 PM PST by NonValueAdded (Killer Joe: babies, jobs, tax cuts, he kills them all.)
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To: NonValueAdded

Holy farook, what were you, a training test dummy, I’ve never heard of so many.


16 posted on 02/24/2021 7:34:21 PM PST by crosdaddy
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To: billorites

Lol


17 posted on 02/24/2021 7:37:15 PM PST by martin_fierro (< |:)~)
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To: crosdaddy

IDK, six from each side, they said All clear, thank God, but still ... All for a 4.5 PSA result. Definitely BPH, though.


18 posted on 02/24/2021 7:47:36 PM PST by NonValueAdded (Killer Joe: babies, jobs, tax cuts, he kills them all.)
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To: NonValueAdded

Ugh,glad it turned out ok, but dang.


19 posted on 02/24/2021 7:51:44 PM PST by crosdaddy
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To: Wilderness Conservative

Beat me to it.


20 posted on 02/24/2021 8:19:34 PM PST by from occupied ga (Your government is your most dangerous enemy)
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