Zelenko Zinc Hydroxychloroquine Doxy or Zith for advanced COVID cases

Daughter's friend's mom is in ICU with COVID-19. She is not on ventilator, getting oxygen but going to use feeding tube because when she eats, oxygen goes down. She is early 60s...I don't know of any co-morbidities.

Anyone know if Zelenko protocol can be used for a late-case but prior to ventilator...

>>The cost of vitamin D is about a penny for 1000 IU, so this treatment costs less than a dollar.

That would seem to be reason enough for our current Federal public health edifice to not consider it.

Can you tell I’m a bit cynical about things?

From the Spanish study:

“Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study”:

" Nevertheless, calcifediol may have some advantages over native vitamin D. It has a more reliable intestinal absorption (close to 100 %) and can rapidly restore serum concentrations of 25OHD as it does not require hepatic 25-hydroxylation. This is especially relevant in clinical situations whereby rapid restoration of serum 25OHD is desirable and CYP2R1 expression is compromised. Such impaired CYP2R1 activity has been well demonstrated in several animal models [41] and has also been observed in patients with COPD or asthma [42]. In addition, calcifediol is more potent when compared to oral vitamin D3 [43]. In subjects with a deficient state of vitamin D, and administering physiological doses (up to 25 μg or 1000 IU daily, approximately 1 in 3 molecules of vitamin D appears as 25OHD; the efficacy of conversion is lower (about 1 in 10 molecules) when pharmacological doses of vitamin D/25OHD are used. [42]"

Because calcifediol is more potent and faster acting than the vitamin D3 sold by Swanson and others, there is an increased risk of overshooting and reaching a toxic level. This risk has to be weighed by the prescribing physician, who will no doubt use frequent tests of vitamin D serum level.

Thank you for your input and prayers.

I am not sure what treatment protocols are being employed...Brief message from family that Ann is not doing well...chest x-ray is not looking good and she has delirium.

Any additional input would be appreciated.

More importantly, your prayers for her family...Her daughter
was diagnosed with leukemia last Thanksgiving, so the family has gone thru a lot.

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