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Novel antioxidant makes old blood vessels seem young again
Hypertension/University of Colorado at Boulder/Science Daily ^ | April 19, 2018 | Matthew Rossman, et al

Posted on 09/07/2020 5:24:35 PM PDT by ConservativeMind

Older adults who take a novel antioxidant that specifically targets cellular powerhouses, or mitochondria, see age-related vascular changes reverse by the equivalent of 15 to 20 years within six weeks, according to new University of Colorado Boulder research.

The study, published this week in the American Heart Association journal Hypertension, adds to a growing body of evidence suggesting pharmaceutical-grade nutritional supplements, or nutraceuticals, could play an important role in preventing heart disease-the nation's No. 1 killer. It also resurrects the notion that oral antioxidants, which have been broadly dismissed as ineffective in recent years, could reap measurable health benefits if properly targeted, the authors say.

"This is the first clinical trial to assess the impact of a mitochondrial-specific antioxidant on vascular function in humans," said lead author Matthew Rossman, a postdoctoral researcher in the department of integrative physiology. "It suggests that therapies like this may hold real promise for reducing the risk of age-related cardiovascular disease."

Half took 20 milligrams per day of a supplement called MitoQ, made by chemically altering the naturally-occurring antioxidant Coenzyme Q10 to make it cling to mitochondria inside cells.

The other half took a placebo.

The researchers found that when taking the supplement, dilation of subjects' arteries improved by 42 percent, making their blood vessels, at least by that measure, look like those of someone 15 to 20 years younger. An improvement of that magnitude, if sustained, is associated with about a 13 percent reduction in heart disease, Rossman said. The study also showed that the improvement in dilation was due to a reduction in oxidative stress.

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine
KEYWORDS: dsj03; nutrition; pill
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My wife and I took this for some months without issue. I found that ergotheinine, found in certain mushrooms, does about the same thing, but the mitochondria has a way to regenerate that antioxidant molecule for up to a month, while this only lasts a day or two before it needs to be replaced in the mitochondria. Still, it appears to work.

You can order MitoQ from various stores.

1 posted on 09/07/2020 5:24:36 PM PDT by ConservativeMind
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To: ConservativeMind

Maybe Byedone is taking that medicine.


2 posted on 09/07/2020 5:26:45 PM PDT by HighSierra5
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To: ConservativeMind
"Novel antioxidant makes old blood vessels seem young again..." Alcohol does the same thing...for awhile.😎
3 posted on 09/07/2020 5:30:37 PM PDT by Bonemaker (invictus maneo)
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To: ConservativeMind

btt


4 posted on 09/07/2020 5:34:55 PM PDT by chiller (Davey Crockett said: "Be sure you're right. Then go ahead'. I'm going ahead.)
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To: ConservativeMind

Only $170 for 3 bottles of 60 each at Amazon.


5 posted on 09/07/2020 5:42:23 PM PDT by moovova (https://therealjoe.com/)
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To: moovova

It isn’t cheap. We found shiitake, maitake, oyster, porcini, and a few others had varying amounts of a similar substance and went went changing our diets to eating mushrooms whenever possible.

They are also low-carb and have other beneficial substances.


6 posted on 09/07/2020 5:58:11 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ckilmer

Ping, Sir.


7 posted on 09/07/2020 5:59:03 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

What kind of mushrooms?


8 posted on 09/07/2020 6:04:14 PM PDT by Flaming Conservative ((Pray without ceasing))
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To: ConservativeMind

The product MitoQ has been found to cause unintended and negative side effects

See here

The Targeted anti-oxidant MitoQ causes mitochondrial swelling and depolarization in kidney tissue, PHYSIOLOGIAL REPORTS, APRIL 2018.


9 posted on 09/07/2020 6:05:03 PM PDT by WLusvardi (Drudge Fudges)
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To: Flaming Conservative

The smoking kind?


10 posted on 09/07/2020 6:12:42 PM PDT by Jyotishi (Seeking the truth, a fact at a time.)
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To: ConservativeMind

Health, BTTT


11 posted on 09/07/2020 6:12:43 PM PDT by Balding_Eagle ( The Great Wall of Trump ---- 100% sealing of the border. Coming soon.)
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To: ConservativeMind

“It isn’t cheap.”

I don’t know... A dollar a day isn’t much different than a low-end prescription drug with a decent insurance plan. I guess it’s not that expensive if it does what it says. You think it’s beneficial?


12 posted on 09/07/2020 6:16:22 PM PDT by moovova (https://therealjoe.com/)
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To: ConservativeMind
What dose did they give?


13 posted on 09/07/2020 6:17:42 PM PDT by Right Wing Assault (Die-ggl,TWT,FCBK,NYT,WPo,Hwd,CNN,NFL,BLM,CAIR,Antf,SPLC,ESPN,NPR,NBA,ARP,MSNBC)
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To: ConservativeMind
It isn’t cheap.

If the dose is only one pill, then it IS cheap. One dollar a day or $365 a year if it works. Cheaper than a lot of things we do. Even if you need 3 a day, that's still cheap if it works.


14 posted on 09/07/2020 6:21:03 PM PDT by Right Wing Assault (Die-ggl,TWT,FCBK,NYT,WPo,Hwd,CNN,NFL,BLM,CAIR,Antf,SPLC,ESPN,NPR,NBA,ARP,MSNBC)
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To: ConservativeMind

This stuff is available on Amazon at $73.00 a bottle for a one month supply. It’s proprietary to a company in New Zealand.


15 posted on 09/07/2020 6:31:04 PM PDT by ocrp1982
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To: Flaming Conservative

I list them in post #6.


16 posted on 09/07/2020 6:33:43 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: WLusvardi

Excellent catch!

We noticed no issues during the four months or so we tried it. I will need to read that study.

We do this to be able to help both ourselves and others with what we took. I don’t want to encourage taking anything I haven’t taken myself.


17 posted on 09/07/2020 6:36:26 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Right Wing Assault

My wife and I took 10 mg a day.

The study subjects took 20 mg a day.


18 posted on 09/07/2020 6:39:59 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: Bonemaker

Lol

A lot of trying to live longer going on around here. Quality not quantity. although when it comes to alcohol both are important :-)


19 posted on 09/07/2020 6:48:08 PM PDT by dp0622 (I DON'T KNOW WHAT TO DO?? ABOUT THE COVID GODFATHER I DON'T KNOW WHAT TO DO. YOU CAN ACT LIKE A MAN!)
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To: ConservativeMind

Assuming you had positive results, how did you gauge them? (As in lower BP reading compared to a baseline; just felt better, etc.)


20 posted on 09/07/2020 6:52:05 PM PDT by Chewbarkah
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