Posted on 05/05/2020 7:33:51 AM PDT by SeekAndFind
An Italian pharmacology scholar has claimed that COVID-19 damages the hemoglobin, thus impairing the ability of red blood cells to transport oxygen throughout the body, affecting the lungs and leading to Acute Respiratory Distress Syndrome (ARDS).
In an explanation of her thesis to The Jerusalem Post, Annalisa Chiusolo said that her theory provides the answers to several questions about the novel coronavirus, including the higher vulnerability demonstrated by men, particularly diabetics, to becoming seriously ill from the virus, as well as the lower rate of COVID-19 infection among pregnant women and children. Chiusolo believes that understanding this mechanism can pave the way for a quicker discovery of highly effective drugs for treating the virus.
Chiusolo who is a graduate of the Faculty of Pharmacy of the University of Perugia, Italy, and works as a pharmacist in the country has published her theory in some of the leading Italian newspapers. According to Chiusolo, SARS-CoV-2 is dependent upon porphyrins for surviving and possibly for replicating, making it attack hemoglobin, the protein that carries oxygen in the blood, resulting in less oxygen available for the body. As a result of less oxygen, carbon dioxide gets accumulated.
Chiusolo has also evaluated the use of hydroxychloroquine to treat SARS-CoV-2, and has found that in addition to having an antiviral and immunomodulatory effect, the drug binds to the ferriprotoporphyrin of the ecgonine methyl ester (EME), thereby blocking the key enzyme of malaria. Ferriprotoporphyrin is the group responsible for the oxygen binding of hemoglobin. Chiusolo believes that a similar mechanism can be used against SARS-CoV-2. Her theory is supported by a study by a Chinese university demonstrating that SARS-CoV-2 binds to the beta chain of hemoglobin, thereby inhibiting EME metabolism.
According to Chiusolo, hydroxychloroquine could act as a prophylactic, thus preventing or limiting the symptoms of COVID-19 while a vaccine is being formulated that specifically stimulates the body’s antibody response. Chiusolo believes that hydroxychloroquine could make the patient immune to COVID-19 and/or limit its side effects, but admitted that the drug does has some severe side-effects, especially among patients having heart disease.
New Hydroxychloroquine data
https://www.medrxiv.org/content/10.1101/2020.04.27.20073379v1
https://blogs.sciencemag.org/pipeline/archives/2020/05/04/hydroxychloroquine-update-may-4
https://www.sciencedirect.com/science/article/pii/S092485792030145X?via=ihub
bump
This is what our FDA says are the side effects of Plaquenil https://www.drugs.com/sfx/plaquenil-side-effects.html
Not a easy drug to take.
for the idiot running around implying he is a DR...and he may very well be..that is spending a lot of time bashing Gilead and remdesivir..just saw where Patient 0 in Seattle who came from Wuhan who recovered was given that drug
also for that idiot..thalessemia is not rare in Italy...and causes the blood to have problems with oxygen
It is so terrible. Ban HCQ now!
Oh yes we believe what the FDA has to say.
The point is; Ask not what the government can do for you but what does the government do to you. And it has not been good.
And by the way why are they so amped up about the Gilead drug. How much $$$$$ is involved and who has their fingers on it.
Been lied to for most of my 84 years so I can’t find it in me to believe anything that comes from the government.
Aspirin side effects (oral)
Tell your doctor right away if you have any serious side effects, including:
•Easy bruising/bleeding
•Difficulty hearing
•Ringing in the ears
•Signs of kidney problems
•Persistent or severe nausea/vomiting
•Unexplained tiredness
•Dizziness
•Dark urine
•Yellowing eyes/skin
Ban ASPIRIN NOW!
We need a new FDA. That side effect listing was unbelievable and so untrue. I took it daily for years just like hundreds of thousands of other people do now and never experienced even one of those side effects.
The best theories I have seen all lead to the conclusion that the Coronavirus attacks the lungs and inhibits the transfer of oxygen and carbon dioxide to and from the lung cells.
My personal favorite is based on the idea that the virus attacks an enzyme that mediates the chemical reactions in the lung cells to maintain a proper balance. The virus disables that enzyme.
The reason I like this theory is that Hydroxycloroquine appears to protect that enzyme so the virus cannot interfere with the normal lung function. But it doesn’t kill the virus and it needs to be applied early in the cycle. Another fact that seems well established.
Nobody gets rich from an effective, safe, generic drug.
Some of these claims sound like snake oil BS to me. What I’ve read about and seen so far is that the beer virus doesn’t kill people itself. It’s not ebola. It doesn’t dissolve flesh and turn people into bled-out gumbo. Normally, it just proceeds like a common cold. For an unfortunate few, though, they are basically “allergic” in a sense and they get a massive autoimmune reaction that does the actual damage. THAT is the problem at hand RIGHT NOW. Too many nerds, even very intelligent nerds tend to lose focus of that. They babble on about “eradicating the virus” or “stopping the virus replication”. Who cares about that? If you can prevent the autoimmune storm and prevent death, then the beer virus turns back into just another stupid cold.
HCQ is a drug used to treat Lupus, which is an autoimmune disorder. (Among other uses such as Malaria) It’s known to be very safe, especially for short term use. It’s literally been used by millions of people for 75 years. There is very little downside to trying it. It actually makes some sense that it might prevent or mitigate the autoimmune storm in the beer virus, if given soon enough before the severe physical damage has already occurred to the victim’s lungs.
I’m getting tired of articles from dubious websites breathlessly claiming this is some sort of “cure”. I seriously doubt that it cures anything. If it simply prevents death and permanent lung damage, that’s good enough. The virus itself “cures” itself in a couple of weeks like any other common cold if you can prevent the aforementioned secondary effects.
Focus! Take care of the problem at hand RIGHT NOW with what you have RIGHT NOW. People who are having life-threatening autoimmune reactions to this virus don’t have months and months to wait for the nerds at the FDA navel gaze over some expensive new “treatment” or “vaccine”. At least TRY to help them NOW, damn it!
You are far too logical for the times we are living in.
feeling that others can hear your thoughts
feeling, seeing, or hearing things that are not there
wtf?
From an article in 2010:
A little over 25 years ago a paper was published in the journal Science showing that BHT, a common food preservative, could inactivate herpes simplex and other lipid-coated viruses in lab dishes. Two years later another paper in the same journal reported similar results, but this time in live animals – dietary BHT could prevent chickens from dying of Newcastle disease. Like herpes simplex, NDV (the virus that causes Newcastle disease) is lipid-enveloped – its nucleic acid core is sheathed in a fatty membrane. Viruses of this type require an intact membrane to be infective. BHT seems to work against such viruses by disrupting their viral membranes.
Ok - the Wuhanic Plague has an E protein structure, or envelope, made of lipids. That’s why hand washing works, soap and water destroy the fatty lipid envelope. Without the envelope, the S protein spikes have no structure to bind to our cells, and the RNA contained inside the envelope become junk. BHT can do this to Covid, just as it does for herpes, H1N1, and HIV. Prophylaxis is preferable to treatment.
Why don’t you ever hear about it? Simple - money. Amazon sells BHT for $30 for 500 capsules. No one gets rich..
Normally, it just proceeds like a common cold. For an unfortunate few, though, they are basically “allergic” in a sense and they get a massive autoimmune reaction that does the actual damage.
+++++
Take a look at my post #10. You are correct that it is the massive autoimmune reaction that is the culprit. That has been fairly widely reported.
My short summary of the Coronavirus - Enzyme theory in that post also predicts the autoimmune reaction and provides a chemical explanation for its cause.
You are on the right track. Keep posting.
Here are the side effects for ASPIRIN from WebMD which takes its information from NIH, CDC, FDA and others:
Aspirin Tablet Side Effects
MILD SIDE EFFECTS
Skin Rash
Stomach Irritation Called Gastritis
Abnormal Liver Function Tests
Black Tarry Stools
Bleeding Gums
Decreased Appetite
Drowsiness
Erythema Or Skin Redness
Hematoma, A Collection Of Blood Outside Of The Blood Vessels
Indigestion
Itching
Nosebleed
Ringing In The Ears
MODERATE SIDE EFFECTS
Conditions Of Excess Stomach Acid Secretion
Heartburn
Irritation Of The Stomach Or Intestines
Nausea
Stomach Cramps
Vomiting
SEVERE SIDE EFFECTS
Decrease In Platelet Clotting
Rupture In The Wall Of The Stomach Or Intestine
Significant Type Of Allergic Reaction Called Anaphylaxis
Allergic Reaction Called Angioedema
Blood Disorder Where The Red Blood Cells Burst Called Hemolytic Anemia
Kidney Inflammation Called Interstitial Nephritis
Anemia
Bleeding
Bleeding Of The Stomach Or Intestines
Bleeding Within The Skull
Blistering Of The Skin
Blood Coming From Anus
Bronchospasm
Damage To The Liver And Inflammation
Decreased Blood Platelets
Hives
Inflammation Of The Skin Due To An Allergy
Large Purple Or Brown Skin Blotches
Low Levels Of White Blood Cells
Seizures
Stomach Or Intestinal Ulcer
Trouble Breathing
Wheezing
Looks like ASPIRIN will kill you dead!
Let me tell you something about ‘SIDE EFFECTS’ from one who spent decades designing, monitoring, data gathering, analyzing and publishing results from clinical trials.
IF A PATIENT COMPLAINS ABOUT ANYTHING RELATED TO A TREATMENT OR PRESCRIPTION, YOU WRITE IT DOWN AND BY LAW YOU ADD IT TO THE SIDE EFFECT PROFILE.
That means the side effect list gets longer and longer and longer.
Cathi,
If you take any drug, you are going to die. Just look at #19 above and be informed that breathing causes death.
You’re welcome.
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