Is There a High Blood Pressure and Coronavirus Link?

Web MD ^ | March 21, 2020 | Web MD

[tired&retired]

Ralph Baric, PhD, perked up when he saw that SARS-CoV-2, the virus that causes COVID-19 illness, enters the lungs through ACE2 receptors, and that people with hypertension have worse outcomes than those with any other underlying condition.

"I've thought it needed to be explored in more detail for quite a while," said Baric, a professor of epidemiology, microbiology, and immunology at the UNC Gillings School of Global Public Health in Chapel Hill, North Carolina, who has been studying coronavirus outbreaks for decades.

Researchers and doctors are trying to determine whether the spike in serious COVID-19 illness in those with baseline hypertension is a coincidence of age and general ill health, or if it speaks to the role ACE2 receptors play in both hypertension and COVID-19 infection. And if there is an association, they want to know whether ACE inhibitors help or hurt people at highest risk for severe COVID-19 disease.

During the same session, Zunyou Wu, MD, PhD, chief epidemiologist at the Chinese Center for Disease Control and Prevention, presented data showing that more than 40% of people with severe infection had baseline hypertension.

Reinin–angiotensin–aldosterone system inhibitors, which include ACE inhibitors, cause an increase in the expression of ACE2 receptors, according to a recent comment in Nature Reviews Cardiology.

"The safety and potential effects of antihypertension therapy with ACE inhibitors or angiotensin-receptor blockers in patients with COVID-19 should be carefully considered," write the Chinese researchers.

If there is an association between ACE inhibitors and the virus, "we might be able to reduce the risk of fatal COVID-19 courses in many patients by temporarily replacing these drugs," they write.

"There is probably some direct relationship to the level of ACE2 expression and disease severity," he said. "And it probably plays some role in the age-related" severity trends we've seen in COVID-19.

[PGalt]

INFORMATION/HEALTH/LIFE BUMP!

[EnquiringMind]

The only reason I remember hearing about high blood pressure is because they named Losartan as a medication they were looking at that helped ease the severe symptoms of Covid-19, and that is the med I have been taking for years. They also named a BP med that could have the opposite, negative effect.

[tired&retired]

Antibody test was not available.

I had no active symptoms, so no test was performed.

[null and void]

Starting the day on a high (pressure) note...

Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

The false positive rate was 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

If a quarantine saves just one child's or one old fart’s life, it's worth it.

[null and void]

Bummer.

[lepton]

Ralph Baric, PhD, perked up when he saw that SARS-CoV-2, the virus that causes COVID-19 illness, enters the lungs through ACE2 receptors, and that people with hypertension have worse outcomes than those with any other underlying condition.

---

Yeah. It struck me as important too - especially since it isn’t really an indicator for the flu except in extreme cases. Which also says that COVID-19 is killing different people than would be killed by the flu, even if generally in similar age brackets.

[dp0622]

Yeah there’s a Definite Connection

I keep seeing a MILLION articles Everywhere posted by Faggots who are Terrified of Everything and my Blood Pressure Goes Way The #### up!!

[tired&retired]

Odd thing was, I was traveling in a small group of a dozen people, mostly MD’s from around the world.

We all piled in a van, or on boats together with tight quarters. Several others developed the dry cough and illness after me, but got better as we all started taking anti malaria medicine at the same time.

[null and void]

but but but but but hydroxychloroquine doesn’t work! </Dr. Fallacy>

[LucyT]

.

PING

Check out article and # 1.

[Mariner]

I wish I could swap my Lisinopril for something else that works and has few side effects.

What I know is on the days I do HIIT, I don’t need the pill and if I take it my BP goes too low.

But I can’t do HIIT every day.

Maybe if I give up salt and alcohol entirely, and get in a 30 min walk...I could be OK at 150/90? I think that was just borderline in the olden days...

[DoodleBob]

Agnes illuminated me to the BMI link to this and other viruses. I was blown away, but it was informative.

Whoda thunk FR would be more informative than The Lancet or NEJM? Thank you.

[BwanaNdege]

Thank you for that detailed information.

Could you provide a Link for me to pass along to my Primary Provider?

Thanks!

[allendale]

Go to the NEJM Journal Watch. Reference the article entitled “Ace inhibitors and ARBs during COVID 19 pandemic” date April 9, 2020.

[tired&retired]

I was taking Malarone which is stronger than Chloroquine, but in the same family.

It is a combination of Atovaquone/Proguanil and is anti fungal and anti parasite.

Ironically, it is also used to treat “Crazy Cat Lady” disease or toxoplasmosis.

[Jane Long]

Someone should start a thread with a listing of all of the names and organizations that have called for a global vax and global/centralized governance of said vax/med supplies.

It mirrors closely to what the “mock”/not to mock pandemic simulation film, Event 201, produced late last year by Gates/CDC, et al, had called for.

[EBH]

I am just going to throw this out here, because it should be further investigated. All the blood pressure medication recalls last year...some supposedly for ‘cancer links’ and others for “chemical contaminants.” See: https://abcnews.go.com/Health/blood-pressure-medication-recall/story?id=59585424

How many of these recalled drugs were made in China? And if the drugs were contaminated is there a corollary to Sars-Cov-2 making people more susceptible than normal?

[tired&retired]

Thanks... Getting a copy of it now.

[Jane Long]

That’s quite the group trial/study!

Thanks for posting this.

[Jane Long]

Can you post a link?

Thanks.