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Trump touts 'game changer' drug against coronavirus. What does the study show?
Yahoo News ^ | 03/22/2020 | Jerry Adler, Senior Editor

Posted on 03/22/2020 8:23:49 AM PDT by SeekAndFind

Like all Americans, President Trump can’t wait for the COVID-19 pandemic to be over. And while his administration struggles to get supplies and equipment out to hospitals facing critical shortages, he holds out hope that the disease, for which there is currently no proven treatment, can be eradicated with one stroke, by a medical coup.

[SNIP]

Trump has been touting the potential of hydroxychloroquine for several days, noting that it has already been approved by the FDA for treating malaria and rheumatoid arthritis. That means it has been tested for safety (although it can have side effects, some of them unpleasant or dangerous) and can be prescribed by any doctor for any legitimate medical purpose, including so-called “off-label” uses. Azithromycin is a well-known antibiotic frequently prescribed for pneumonia, familiar to many Americans under the brand name Zithromax Z-Pak.

Trump’s tweet referenced an article in a medical journal, the International Journal of Antimicrobial Agents, which appeared online the day before in preprint, meaning it has not been put through “peer review” by other researchers and may or may not stand up to their scrutiny. The article was based on a single study in France that administered the drug regimen to 26 patients infected with the coronavirus, plus 16 in a control group who received only symptomatic care. Of the 26 who got the drugs, one died — a rate of 3.8%, which is about in line with the usual estimates of mortality from COVID-19. The experimental treatment was stopped for three when they went into intensive care and one dropped out of the study because of side effects.

But the encouraging news from the study was that the people taking the drugs were cleared of the virus — i.e., tested negative — much more rapidly and completely than the control group.

(Excerpt) Read more at news.yahoo.com ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: chinavirusdrugs; chinavirustreatment; coronavirus; covid19; hydroxychloroquine
THE ARTICLE GOES ON TO SAY:

That is very much short of the full clinical trial the Food and Drug Administration typically requires before approving a new drug, which can take a year or more, cost millions of dollars and involve thousands of patients. But, as the authors wrote in explaining why they rushed to publicize their findings, “despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.”

1 posted on 03/22/2020 8:23:49 AM PDT by SeekAndFind
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To: SeekAndFind

“IS” or “COULD BE”.


2 posted on 03/22/2020 8:37:52 AM PDT by rktman ( #My2ndAmend! ----- Enlisted in the Navy in '67 to protect folks rights to strip my rights. WTH?)
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To: SeekAndFind

Article neglects to say that 50 hospitals in Australia are using it, not to mention other countries.


3 posted on 03/22/2020 8:38:49 AM PDT by WildHighlander57 ((WildHighlander57 returning after lurking since 2000)
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To: WildHighlander57

Poland has already approved it and it’s their main drug to use.


4 posted on 03/22/2020 8:43:58 AM PDT by BipolarBob (I survived Covid-19 pandemic scare and all I got was this lousy T-shirt and a depleted 401k account.)
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To: BipolarBob

Thanks!

Related; timeline of President Trump’s actions against the virus:

https://www.freerepublic.com/focus/f-news/3827072/posts?page=1#1


5 posted on 03/22/2020 8:52:24 AM PDT by WildHighlander57 ((WildHighlander57 returning after lurking since 2000)
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To: SeekAndFind

Wonder what Fauci would say if someone asked him “If YOU were diagnosed with covid-19 and your symptoms were getting bad would YOU take hydroxychloroquine and azithromycin?”


6 posted on 03/22/2020 8:54:24 AM PDT by FreedomForce
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To: SeekAndFind

No deaths at Lennox Hill Hospital from the virus after using hydroxychloroquine By M. Dowling March 20, 2020

Dr. William Grace from Lennox Hill Hospital told Laura Ingraham on her show last night that he has been prescribing Hydroxychloroquine to his patients with coronavirus. They have 100 patients and have had zero deaths after the use of Hydroxychloroquine.

Hydroxychloroquine is the less toxic version of Chloroquine.
Grace said that a big reason older people die from the coronavirus is that their lungs fill up with fluid as part of an immune response to the virus. Hydroxychloroquine works, Grace notes, in both inhibiting the immune response and inhibiting the replication of the virus.


7 posted on 03/22/2020 8:57:02 AM PDT by JayGalt (You can't teach a donkey how to tap dance. Nemo me impune lacessit!)
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To: SeekAndFind

Can’t read this commie bllsht from fricking Yay-Hoo.

Fricking Yayhoos....


8 posted on 03/22/2020 9:05:11 AM PDT by RArtfulogerDodger (peace, Love, and Joy To All, Especially Obama and Democrats)
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To: rktman
The FDA, like other scientists, is used to getting ambiguous results and making decisions which could be wrong.

Because if there is random variability in the data, you have to bite the bullet and accept a hypothesis with, say, a 5% chance you could be wrong.

It’s one thing to demand a 95% certainty to make a decision when you are in a nice, air-conditioned office in perfect health. It’s quite another thing when you are in a hospital bed afraid every breath might be your last. Then “could be wrong” doesn’t matter a whole lot compared to “probably right.” At that point even might be right sounds pretty good.

The other thing is that when your results don’t show a great deal of variability - if all your patients respond positively, none significantly negatively - then you can be 95% sure of your decision with a pretty small sample size.


9 posted on 03/22/2020 9:30:35 AM PDT by conservatism_IS_compassion (Socialism is cynicism directed towards society and - correspondingly - naivete towards government.)
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To: SeekAndFind

New York will start implementing the trial drugs to treat Coronavirus.

NY has acquired:
- 70,000 Hydroxychloroquine
- 10,000 Zithromax
- 750,000 Chloroquine

From the Federal Government.

Trials will start Tuesday.

https://twitter.com/bennyjohnson/status/1241749428492537864

Looks like NY is going to do some trials for us


10 posted on 03/22/2020 9:48:27 AM PDT by Pollard (If you don't understand what I typed, you haven't read the classics.)
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To: FreedomForce

Always a good question...but...there are examples of drugs which have been studied in detail...showed some promise, even approved and failed when used on a larger scale...gut level is that it may help...probably should be approved under compassionate use for the very ill and results should be reported IMMEDIATELY...analyzed...and recommendations made...ASAP. I am not sure if Fauci is directing those efforts but somebody should be, like, right now.


11 posted on 03/22/2020 9:58:11 AM PDT by Getready (Wisdom is more valuable than gold and diamonds, and harder to find.)
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To: Getready

The President needs to stop with all the false hope. We need at least 100,000 deaths and 48 news conferences by Joe Biden to have a chance at this election. I say that with sarcasm but in the minds of Michael Moore and Rachel Maddow those demons would trade a few 100,000 Americans if they could get socialists elected. It angers them we may be able to run this thing down in a few months. Why we can’t debate them or compromise with them, we need to defeat them at thew ballot box and the Antifa style ones we need to send to the graveyard.


12 posted on 03/22/2020 10:03:41 AM PDT by pburgh01 (Negan all the MSM)
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To: SeekAndFind

If someone knows statistics, the French results are significant beyond doubt.


13 posted on 03/22/2020 10:08:01 AM PDT by Governor Dinwiddie (Guide me, O thou great redeemer, pilgrim through this barren land.)
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