Posted on 03/16/2020 9:13:00 AM PDT by SeekAndFind
The most promising drug to potentially treat coronavirus -- Gilead Sciences' remdesivir -- is being given a second shot at clinical trials after three seriously-affected patients in the US treated with remdesivir recovered albeit with some side effects.
According to a report in Statnews on Monday, remdesivir is now being tested in five COVID-19 clinical trials and the first trial results are expected next month.
As of now, there are no approved therapies for any coronavirus infection, and "remdesivir is the farthest along in the development process of any candidate."
"There's only one drug right now that we think may have real efficacy. And that's remdesivir," Bruce Aylward of the World Health Organisation (WHO) said.
A randomised, controlled clinical trial to evaluate the safety and efficacy of the investigational antiviral remdesivir in hospitalised adults diagnosed with COVID-19 began at the University of Nebraska Medical Center (UNMC) in Omaha late last month.
According to the US National Institute of Health (NIH), this was the first clinical trial in the US to evaluate an experimental treatment for COVID-19.
A paper describing the first 12 patients with COVID-19 in the US started circulating ahead of an official peer review.
"All three patients treated with remdesivir recovered, but they also reported significant gastrointestinal symptoms. Investigators also noticed elevated liver enzyme levels in their blood samples," according to a report in The Motley Fool.
Remdesivir is an investigational broad-spectrum antiviral treatment.
It was previously tested in humans with Ebola virus disease and has shown promise in animal models for treating Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS), which are caused by other coronaviruses.
Clinical trials of remdesivir are also ongoing in China.
(Excerpt) Read more at sify.com ...
From the source I cited:
Chloroquine:
* Designed to treat: Malaria
* Evidence for: Lab tests against COVID-19
* Evidence against: No data
Remdesivir
* Designed to treat: RNA viruses (MERS, Ebola)
* Evidence for: Lab tests against the COVID-19 virus; animal tests against MERS; tests in people with Ebola
* Evidence against: Not as helpful as other drugs against Ebola
Thanks for synopsis on chloroquine & remdesivir!
This shit needs to be expedited to the front lines if not already!
There is a story from Australia that they have found two drugs completely eradicate he virus supposedly- and one of the drugs was an older HIV drug- not sure if it’s the same one in this thread or not- if so- they say hte drugs have been out a long time are are ‘very well tolerated’- the article below does not mention what the drug is though-
https://www.freerepublic.com/focus/f-chat/3825140/posts
Could you share what kind of colloidal silver you use? I have a half full bottle (small bottle). I guess I need more?
RE: There is a story from Australia that they have found two drugs completely eradicate he virus supposedly-
Yes, the tests were done IN-VITRO though.
This work was done by a team headed by Professor David Paterson, director of the University of Queensland Centre for Clinical Research and infectious disease physician at the RBWH
The hopeful sign is this ( from the article in the link you showed ):
“There have already been patients treated with these in Australia and there’s been successful outcomes but it hasn’t been done in a controlled or a comparative way,” Prof Paterson said.
The drugs would be given orally, as tablets.
FINALLY, a use for all that toilet paper!
Thank you.
good point- it’s been used before, so side effects should be known-
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