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Will Gilead Sciences Remdesivir Help Arrest the Coronavirus? Here's What We Know From the Small Sample Size
Real Money ^ | 03/12/2020 | By STEPHEN GUILFOYLE

Posted on 03/12/2020 11:59:39 AM PDT by SeekAndFind

No. Not a cure. Not a vaccine. A treatment. A treatment that is effective in at least slowing the further spread of illness to global populations, might cure not just financial markets, but global economies prior to further exacerbation of negatively trending conditions. This treatment I speak of is known as Remdesivir. The firm behind that name is Gilead Sciences (GILD) . The stock is a member of my "Virus" group, and has easily outperformed the broader market as well as most of my book as equities have sold off hard.

Remdesivir

Since the very beginning of public cognizance that there was a novel coronavirus working its way through China, biotechnology stocks, or at least those already working on anti-viral medications meant for either Ebola of HIV, have become quite volatile. One that had not really been all that volatile for an entire year had been Gilead Sciences. It's volatile now.

Gilead has been a leader in the development of anti-virals. In recent days, the firm has received some positive results in clinical trials for two different HIV treatments, Descovy and TLR-7. Remdesivir had been under development for the treatment of Ebola, and had thus far not truly distinguished itself. That said, this drug was believed to maybe have an ability to work toward at least some positive effect versus Covid-19 in China and is now undergoing clinical trials there. Actually two studies. Remember, the term novel in front of the word coronavirus means "new" as in we have no natural immunity.

China

The fact that Remdesivir had reached mid-stage trials already made the drug ready for shipment to China ahead of other potential treatments that other bio-techs might be working on from scratch, or built upon prior works. What we have known for weeks now is that at least 230 patients in China diagnosed with a severe case of Covid-19 had been enrolled out of the 453 patients that had been hoped for. Results for these trials are not expected until April. However, there has been some hope expressed from within the analyst community that perhaps sometime this month (March) an update might be made public.

What we know is from an extremely small sample size. Apparently two patients in France were treated with Remdesivir for Covid-19. One recovered after about three weeks and the other died. A third patient, profiled in the New England Journal of Medicine (known to be 35 years of age), recovered "quickly".

The question is this. Will Remdesivir show enough efficacy in severe cases to warrant a global deployment as part of the effort to arrest the outbreak, or at least buy time as we await something specifically designed to treat this illness? Or warmer weather. If that even helps.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: chloroquine; coronavirus; gilead; remdesivir

1 posted on 03/12/2020 11:59:39 AM PDT by SeekAndFind
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To: SeekAndFind

Could an old malaria drug help fight the new coronavirus?
http://freerepublic.com/focus/f-news/3823805/posts


2 posted on 03/12/2020 12:03:58 PM PDT by Zhang Fei (My dad had a Delta 88. That was a car. It was like driving your living room.)
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To: SeekAndFind

“Will Gilead Sciences Remdesivir Help Arrest the Coronavirus?”

Maybe in a year it will help, after it works through the bureaucracy. But it does sound like it has promise in making recovery a bit easier and faster.


3 posted on 03/12/2020 12:08:17 PM PDT by LouieFisk
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To: SeekAndFind

Colloidal silver works and has been around thousands of years

It kills all viruses and bacteria and this is all proven and white papers be a transmission electron microscopy

Silver is in 20,000+ medical products approved by the FDA

So why does the medical establishment claim that silver internally does not work effectively despite tremendous amounts of data to the contrary?

This is very simple because you can make it for free


4 posted on 03/12/2020 12:09:45 PM PDT by Truthoverpower (The guv mint you get is the Trump winning express !)
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To: Truthoverpower

What do you say to this :

https://www.ftc.gov/news-events/blogs/business-blog/2020/03/ftc-fda-warn-companies-making-coronavirus-claims

When public health concerns hit the headlines, some companies rush to the market with products advertised to prevent or treat the problem. We’re seeing the same thing with the Coronavirus. But do those businesses have proof for their advertising claims, as the FTC requires? And have their products been approved, cleared, or authorized by the FDA? The FTC and FDA just sent warning letters to seven companies raising concerns about their Coronavirus-related products. If your business is making Coronavirus claims, stop. Pay special attention to what the letters say. The FTC also has advice for consumers about protecting themselves from Coronavirus scams.

Here are the companies that received the FTC-FDA warning letters and some of the products they’re pitching.

Jim Bakker and The Jim Bakker Show. (Yes, that Jim Bakker you may remember from TV in the the 80s.) The FTC-FDA warning letter cites antiviral claims for Silver Sol Liquid, Silver Sol Gel, and Silver Lozenges made in a video titled A Close Look at What’s Not Being Said About the Coronavirus, on social media, and on websites.

Herbal Amy, Inc. The warning letter calls into question claims the Idaho firm is making for multiple products, including a “Coronavirus Protocol.” According to ads, “The formulations are preventative as well as specific for acute infections.”

N-Ergetics. The FTC-FDA letter quotes claims the Oklahoma-based business makes for colloidal silver products. According to its website, “Colloidal Silver is still the only known anti-viral supplement to kill all seven of these Human Coronaviruses,” and “This Chinese Wuhan Flu Pneumonia has a non-traditional remedy that has successfully killed coronaviruses from the flu virus to pandemic diseases, in vitro, for over 100 years. . . .”

Vital Silver. The Florida-based company makes numerous claims on Facebook and on its website that the FTC and FDA cite in the warning letter – for example, “So it’s actually widely acknowledged in both science and the medical industry that ionic silver kills coronaviruses” and “[R]esearch efforts have demonstrated that silver was found to effectively deactivate the human coronavirus strain 229E, a virus linked to SARS . . .”

Quinessence Aromatherapy Ltd. On Twitter and on its site, the UK company advertises “Essential Oils To Protect Against Coronavirus” and lists products it sells that are “The most powerful anti-virus essential oils to provide defence against coronavirus.” Those are among the claims cited in the FTC-FDA warning letter.

GuruNanda, LLC. California-based GuruNanda asks on its website, “Just what is this new Coronavirus, and how can you prevent and/or treat it?” According to the company, its frankincense product is a way to “decrease your chances of becoming infected.” The warning letter cites those claims and others the company makes on Twitter and Facebook.

Vivify Holistic Clinic. According to the FTC-FDA warning letter, the Canadian company makes a variety of claims on its site and on Facebook – for example, “Regarding the Wuhan Coronavirus: Stephen Buhner . . . has done extensive research on coronaviruses . . . and has treated them very successfully using his protocols.” The company also makes recommendations about the use of its product “for a preventative dose” and “for an infection dosage.”

FTC Coronavirus pageWhat is the FDA telling these companies? “You should take immediate action to ensure that your firm is not marketing, and does not market in the future, products intended to diagnose, mitigate, prevent, treat or cure COVID-19 that have not been approved, cleared, or authorized by the FDA.”

The FTC reminds those businesses it’s illegal “to advertise that a product can prevent, treat, or cure human disease unless you possess competent and reliable scientific evidence, including, when appropriate, well-controlled human clinical studies, substantiating that the claims are true at the time they are made.” Furthermore, because “there currently are no vaccines, pills, potions, lotions, lozenges or other prescription or over-the-counter products available to treat or cure coronavirus disease 2019 (COVID-19),” the FTC says those companies “must immediately cease making all such claims.”

Recipients of the letters have 48 hours to tell the FDA and FTC what they’re doing to address the issues the agencies have raised. The letters also include a reminder of the ramifications of violating the law. If a firm fails to follow through with immediate corrective measures, the FDA may take enforcement action, which could involve criminal prosecution. The FTC may seek a federal court injunction and financial remedies for consumers.


5 posted on 03/12/2020 12:13:20 PM PDT by SeekAndFind (look at Michigan, it will)
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To: Truthoverpower

Supplies and process?


6 posted on 03/12/2020 12:16:13 PM PDT by Norski
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To: SeekAndFind

Grace Hatton If you think about the virus for a moment and assume some of the claims that tens of thousands are already infected, but mostly not showing symptoms, that would suggest that in a week or two all those thousands of people would probably be just as immune as if they had been vaccinated. Some of this will take care of itself.
Remember West Nile Virus? Today probably tons of folks have antibodies to it although some people did suffer terrible after effects from that virus most never knew they had been exposed.


7 posted on 03/12/2020 12:27:20 PM PDT by finnsheep
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To: SeekAndFind

Gild has been touted by our gov, by name, as having the most promise in the fight against covid 19


8 posted on 03/12/2020 12:28:32 PM PDT by spacejunkie2001
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To: spacejunkie2001

And yet the stock is tanking like every other stock.


9 posted on 03/12/2020 12:31:44 PM PDT by Old Yeller (Auto-correct has become my worst enema.)
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To: Old Yeller

probably because no results have been released. and....the market is down 25%(?)


10 posted on 03/12/2020 12:41:09 PM PDT by spacejunkie2001
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To: SeekAndFind

South Korea has been using some sort of zinc based spray to the throat which has greatly slowed the spread of the virus in those confirmed with the ChiCom Wuhan Virus.

There’s also been reports about the efficacy of Vitamin C.

We should be getting our act together on all of it.


11 posted on 03/12/2020 12:42:06 PM PDT by romanesq (8Chan & its child porn are kaput & all the crap with it. Trump-Pence 2020! Magacoalition.com)
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To: romanesq

New treatment methods are being used now. The HIV treatment ones are already approved (so, ready now if they work, they currently have great results). The transfusions using previous patient’s blood shown a lot of progress (and is already approved procedure). A gene sequencing one has been tested and approved for other closely related viruses.

There are over 90 pharmaceutical companies working on a cure and vaccine, several are showing great progress (not factored into the deathrate), Favilavir, Remdesivir, Actemra, REGN3048-3051, blood transfusions from survivors, etc.


12 posted on 03/12/2020 12:51:32 PM PDT by BushCountry (thinks he needs a gal whose name doesn't end in ".jpg")
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To: romanesq

https://www.youtube.com/watch?v=vE4_LsftNKM
Zinc and COQ10.


13 posted on 03/12/2020 12:53:17 PM PDT by Battle Axe (Repent, for the Lord is coming.)
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To: Battle Axe
The HIV treatment ones are already approved (so, ready now if they work, they currently have great results).


14 posted on 03/12/2020 12:55:12 PM PDT by Old Yeller (Auto-correct has become my worst enema.)
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To: SeekAndFind

Bkmk


15 posted on 03/12/2020 1:03:59 PM PDT by sauropod (David Horowitz: “Inside every progressive is a totalitarian screaming to get out.”)
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To: Battle Axe

Thank you Battle Axe, that was good and yes, that’s the stuff:
hydroxychloroquine.

They are using it in South Korea to good effect.


16 posted on 03/12/2020 1:08:34 PM PDT by romanesq (8Chan & its child porn are kaput & all the crap with it. Trump-Pence 2020! Magacoalition.com)
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To: All
I think Jim Bakker was hawking colloidal silver spray as coronavirus killer until the gubmint asked him to shut it down unless he wanted to go back to the crossbar hotel.
17 posted on 03/12/2020 1:16:43 PM PDT by BipolarBob (Hi! I'm Joe Biden and I forgot this message.)
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To: LouieFisk

“Maybe in a year it will help, after it works through the bureaucracy. But it does sound like it has promise in making recovery a bit easier and faster”

The only $hit that has hit the fan is fear / panic / the stock market (in the USA) If it really hits medically there is no way this drug will be required to go through the normal FDA process if found effective. Gileads drug is being developed to treat a similar virus, it is not known (to the public) yet if it is effective for CV. If effective there will be a heavy price to pay for politicians standing in the way. Gilead might already have an idea of the efficacy of Remdesivirhas, it has ramped up production fast and beyond the the needs for the approximate 1,000 patients that will be part of the phase III testing.


18 posted on 03/12/2020 1:44:00 PM PDT by DAC21 ( and Naflet had demint)
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To: DAC21

If it were up to me, I’d make it available for use in treating CV19 yesterday. Take the ones most likely to not pull through first, tell them whatever risk there may be and let them choose. I suspect you’d get a lot of willing “guinea pigs” who would want to try it.


19 posted on 03/12/2020 1:51:05 PM PDT by LouieFisk
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To: SeekAndFind; nuconvert

98 clinical trials

https://clinicaltrials.gov/ct2/results?cond=Corona+Virus+Infection&term=&cntry=&state=&city=&dist=


20 posted on 03/14/2020 8:55:38 AM PDT by AdmSmith (GCTGATATGTCTATGATTACTCAT)
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