Posted on 06/24/2018 6:59:46 AM PDT by ConservativeMind
Levels of CoQ and the presence of insulin resistance were analysed in a range of experimental laboratory settings, mouse models and samples from humans, as part of an ambitious research collaboration conducted with the University of Sydney, Victor Chang Cardiac Research Institute, Duke University School of Medicine, Garvan Institute of Medical Research, Genentech Inc. and the University of New South Wales.
Concentrations of CoQ were found to be lower in insulin resistant body fat and muscle tissue. When the researchers replenished CoQ, insulin resistance or pre-diabetes was reversed.
"CoQ is found in mitochondria, the power plants in the cells of our body, where it is required for the flow of electricity to the cell's 'motor' which is responsible for energy production," he explained.
"Energy production can also generate reactive chemical species -- often referred to as 'reactive oxygen species' or 'oxidants' -- as by-products, which can be damaging to cells.
"Previous studies have shown that these oxidants can cause insulin resistance. Our study has found that lower mitochondrial CoQ enhanced oxidant formation by mitochondria.
"Importantly, by replenishing CoQ in mitochondria, either in cells or in animals, we were able to restore 'normal' mitochondrial oxidants and reverse insulin resistance."
Published in eLife today, the research provides a missing link in our understanding of how changes in our diet can trigger insulin resistance, said co-lead author Professor David James, Leonard P. Ullmann Chair of Metabolic Systems Biology at the University of Sydney's Charles Perkins Centre.
"Eating a high fat, high sugar diet has long been known to be a major risk factor for obesity and pre-diabetes and our latest work brings us one step closer to understanding how and why," Professor James explained.
"However, oral CoQ supplements may not effectively restore mitochondrial CoQ due to its low absorption," Professor Stocker explained.
(Excerpt) Read more at sciencedaily.com ...
If prediabetic, stop eating breads, pasta, rice, sugars, cereals and the vast majority of “normal” desserts. That leaves unsweetened beans, lentils, and possibly potatoes. Only potatoes would be allowed on a “paleo” diet of these, if you wanted to consider that jump.
Another way to view this is from Glycemic Load. We aren’t buying things above a “2.”
https://academic.oup.com/ajcn/article/76/1/5/4689459
http://care.diabetesjournals.org/content/suppl/2008/09/18/dc08-1239.DC1/TableA1_1.pdf
http://doctormurray.com/wp-content/uploads/2017/09/Glycemic-Load-of-Foods-Table.pdf
However, we do specifically eat two things for dessert that are lower carb and very tasty. From Walmart’s freezer section, “Paleo Cookies”’ from Jimmy’s Cookies and any ice cream from “Enlightened.”
https://www.walmart.com/ip/Jimmy-s-Cookies-Chocolate-Chunk-Paleo-Cookies-18-cookies/179574365
https://eatenlightened.com/
Do you measure your sugar?
I do so I figure that would be a good way to empirically determine whether it helps or not by carefully lowering the dosage of my other meds (Metphormin and a few others).
I am going to give it a shot and I’ll keep yo posted.
it’s alpha lipoic acid and it’s used to supposedly treat peripheral neuropathy- I got peripheral neuropathy from chemo and it did absolutely nothing to help the condition- Some folks say it worked for them- i had no help from it
There are a couple forms of co q10. Basically a form of it primarily located inside cells, and another form of it primarily located outside of the cells.
The organ with the most coq10 is the heart. Sometimes up to ten times as much as the next leading part of the body.
Please work to shift his cravings toward low “net carb” desserts.
My wife and I really like these:
From Walmart’s freezer section, “Paleo Cookies”’ from Jimmy’s Cookies and any ice cream from “Enlightened.”
https://www.walmart.com/ip/Jimmy-s-Cookies-Chocolate-Chunk-Paleo-Cookies-18-cookies/179574365
https://eatenlightened.com/
Reference Bump!
Those paleo cookies look delicious! Thanks for the tip!
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