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This Rub-on Male Hormonal Contraceptive Is About to Be Tested on People
www.sciencealert.com ^ | 21 DEC 2017 | MIKE MCRAE

Posted on 12/21/2017 1:11:03 PM PST by Red Badger

It's a gel, but it doesn't go where you'd think.

If you're a sperm-producer who doesn't want kids, your personal contribution to contraception is currently limited to condoms or the snip.

Needless to say, not everybody likes those choices. But now a topical treatment could add another simple, non-invasive option to the mix - it's a hormonal gel that reduces sperm count when applied to the skin.

Next April, researchers at the National Institute of Child Health and Human Development are expecting to begin clinical trials on this gel, which has been in development for several years.

In 2012 the team conducted a trial on a combination of two gels that successfully saw the number of sperm in their semen drop to less than 1 million per millilitre – a concentration that's far enough below the normal 15 to 200 million sperm per millilitre to actually hamper fertility.

Applying two gels (it had to be done on two different body parts, too) would be quite a hassle though, so now researchers have finally combined the treatment into one easy-to-use application.

The gel is a combination of synthetic versions of the hormones progesterone and testosterone.

The progesterone analogue, called nestorone, competes with the body's testosterone levels, reducing them in the testes just enough to prevent mature sperm from being made. The added boost of testosterone helps keep hormones balanced throughout the rest of the body.

By rubbing half a teaspoon of the quick-drying liquid each day onto a body part, such as the upper arms or shoulders (away from the family jewels is probably best), sperm levels will be kept down for the next couple of days.

The study will take in a few hundred partnered test subjects scattered over the US, Chile, Europe, and Kenya, who are expected to use the treatment over four months while their sperm levels are monitored.

Once they get the thumbs up, the couples are invited to go off all other forms of birth control, meaning for the next year the only thing between the test subjects and parenthood is the gel.

"I am very confident that if men put the gel on every day and apply it correctly, it will be effective," Stephanie Page, principle investigator and a professor of medicine at the University of Washington told Emily Mullin at MIT Technology Review.

Another trial is currently underway to ensure any stray gel rubbing onto a partner isn't cause for alarm.

Male contraceptives have been on the horizon for a while now. But while a number of progressive men are keen to carry their share of responsibility, fanfare isn't as loud as we might expect and not all pharmaceutical companies are clamouring for a piece of the pie.

For one thing, a number of the treatments currently in the pipeline include injections of one sort or another. On paper, that shouldn't scare your average fully grown male, but in reality it may not have everybody rushing out for a shot.

Another hurdle could simply be that a number of men just don't care when it comes to birth control. Or don't make the connection between female contraception and not having a baby.

With potential roadblocks like these in the way, anything that makes the process of male contraception as simple and foolproof as possible is a worthy goal.

Given the nature of clinical trials, even with a best case scenario we shouldn't expect this gel to be available on the market just yet.

But if this treatment passes with flying colours and makes it through red tape and regulations, it would be a great addition to our currently limited contraception choices.


TOPICS: Health/Medicine; Religion; Science; Sports
KEYWORDS: males; testosterone
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To: gathersnomoss

Ben-Gay?


41 posted on 12/21/2017 1:43:00 PM PST by bar sin·is·ter (Climate Scientology - another example of science fiction morphing into a religious cult)
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To: gathersnomoss

https://www.youtube.com/watch?v=INXAe5I42CM

“....and those warts on your d___ aren’t gonna go away, unless you start using topical cream every day.”


42 posted on 12/21/2017 1:44:49 PM PST by dfwgator
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To: dp0622

WIFE: Honey, just came back from the gynecologist and she says I can’t have sex for three weeks.

HUSBAND: What did the dentist say?


43 posted on 12/21/2017 1:45:30 PM PST by bar sin·is·ter (Climate Scientology - another example of science fiction morphing into a religious cult)
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To: dp0622

Your question is irony isn’t it? 5


44 posted on 12/21/2017 1:46:24 PM PST by amihow
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To: WashingtonFire

His female counterpart who does myriad attacks on her healthy body to reduce her God given femininity and fertility so she can catch or keep a guy.$


45 posted on 12/21/2017 1:50:03 PM PST by amihow
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To: Red Badger

“This Rub-on Male Hormonal Contraceptive”

Its called ice.


46 posted on 12/21/2017 1:51:04 PM PST by HereInTheHeartland (I don't want better government; I want much less of it.)
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To: cmj328

Sweeeet.


47 posted on 12/21/2017 1:51:52 PM PST by amihow
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To: Red Badger

“The scientists tell us that SPF from suntan lotions...”

No, they don’t, because scientists know that “SPF” is a just a unit of measurement, like a centimeter or a calorie, and not an actual chemical.


48 posted on 12/21/2017 1:55:18 PM PST by Boogieman
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To: Boogieman

I was talking about the chemicals that produce the SPF..............


49 posted on 12/21/2017 1:56:42 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Red Badger
it's a hormonal gel that reduces sperm count

Hi! Here are our children, Itonlytakesone, Rubbedmewrong and Missedaspot!

50 posted on 12/21/2017 2:00:16 PM PST by Albion Wilde (I was not elected to continue a failed system. I was elected to change it. --Donald J. Trump)
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To: Albion Wilde

.....and BrokenRubber............


51 posted on 12/21/2017 2:03:41 PM PST by Red Badger (Road Rage lasts 5 minutes. Road Rash lasts 5 months!.....................)
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To: Red Badger

"....and then my therapist Tiffany says, tail curling and whisker braiding are next..."

52 posted on 12/21/2017 2:06:42 PM PST by Doogle (( USAF.68-73..8th TFW Ubon Thailand....never store a threat you should have eliminated)))
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To: NEMDF

This is all they should get if they want "free" contraceptives. More effective, and it's cheaper.

(No, I'm not seriously advocating this... but only because permanent sterilization is just as immoral as contraception.)

53 posted on 12/21/2017 2:06:57 PM PST by GCC Catholic (Trump doesn't suffer fools, but fools will suffer Trump. Make America Great Again!)
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To: bar sin·is·ter

Love it! Just not on me...


54 posted on 12/21/2017 2:07:08 PM PST by JayGalt (Let Trump Be Trump)
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To: gathersnomoss

#39, no, but gorilla tape does wonders


55 posted on 12/21/2017 2:08:57 PM PST by VRWCarea51 (The Original 1998 Version)
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To: Red Badger

I’m 71 with several major medical problems. I’d settle for the rub on part


56 posted on 12/21/2017 2:09:49 PM PST by morphing libertarian (Build Kate's Wall)
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To: Red Badger

good....now there will be no excuse, no name calling if someone gets pregnant because now the boys have another way to avoid producing a baby other than refraining from sex,or using a condom.


57 posted on 12/21/2017 2:12:39 PM PST by cherry
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To: bar sin·is·ter

OMG!!! ROFLMAO!!!!!!!!!!


58 posted on 12/21/2017 2:17:49 PM PST by dp0622 (The Left should know that if Trump is kicked out of office, it is WAR!)
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To: amihow

To the extreme!!!!!!

Or I’d be over at KOS :)


59 posted on 12/21/2017 2:18:22 PM PST by dp0622 (The Left should know that if Trump is kicked out of office, it is WAR!)
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To: bar sin·is·ter

Hey!
What are you doing with a picture of my first girlfriend!
NOT NICE!


60 posted on 12/21/2017 2:22:05 PM PST by oldvirginian (Happy Holidays my chapped buttocks. I'm going to Merry Christmas the hell out of everyone i meet!)
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