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New Microscope Ditches The Lenses
CBS News | CNET ^ | 8/4/08

Posted on 08/05/2008 11:18:59 AM PDT by LibWhacker

(CNET) Researchers have come up with a microscopic microscope, tiny enough to fit on a fingertip, that can be cheaply mass-produced and used to scan blood and water for pathogens.

The high-resolution microscope functions without the large and expensive lenses usually associated with such imaging devices. Instead, it combines the chip technology found in digital cameras with "microfluidics," the science of channeling liquid at scales far smaller than a common droplet.

"The whole thing is truly compact -- it could be put in a cell phone -- and it can use just sunlight for illumination, which makes it very appealing for third-world applications," said Changhuei Yang, an assistant professor of electrical engineering and bioengineering at the California Institute of Technology and one of the lead developers of the device.

Yang imagines a range of uses for the so-called optofluidic microscope, which measures about the size of George Washington's nose on a quarter and has the magnifying power of a top-quality optical microscope, according to the Caltech research team.

Health field workers could use it to examine blood samples for malaria and check water for giardia and other parasites. It could be employed on the battlefield. Yang said the microscope could one day even be implanted inside humans to isolate rogue cancer cells circulating in the bloodstream.

"Our research is motivated by the fact that microscopes have been around since the 16th century, and yet their basic design has undergone very little change and has proven prohibitively expensive to miniaturize," said Yang, who is currently in talks with biotech companies about mass-producing the chip, a process he says costs about $10 per microscope.

(Excerpt) Read more at cbsnews.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: compact; lenses; microscope; optofluidic

1 posted on 08/05/2008 11:19:01 AM PDT by LibWhacker
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To: neverdem

Ping list worthy, oh great one?


2 posted on 08/05/2008 11:27:07 AM PDT by bajabaja
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To: LibWhacker
Coming soon: the Nokia cellphone with the in-built 20 MP digicam AND the super hi-res microscope. They say one can shave with it too.

Oh, the wonders of science...

3 posted on 08/05/2008 11:37:30 AM PDT by Apollo 13
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To: Apollo 13
coming soon to a tri-corder near you


4 posted on 08/05/2008 11:49:36 AM PDT by Mr. K (Some days even my lucky rocketship underpants don't help)
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To: Mr. K

LOL! I want one! NOW!


5 posted on 08/05/2008 11:57:19 AM PDT by Apollo 13
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To: LibWhacker

Didn’t Dr. McCoy have one of these in his tricorder on Star Trek 30 years ago?


6 posted on 08/05/2008 11:59:28 AM PDT by CholeraJoe ("Space may be the final frontier, But it's made in a Hollywood basement")
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To: bajabaja; LibWhacker; SunkenCiv
Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging

It appears that this is an open access, pdf linked article after reading the abstract.

7 posted on 08/05/2008 12:07:53 PM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: LibWhacker
I didn't see any mention of depth of field or working distance. I wonder if this could be used in a specimen scope setup for gemological uses where one wants to focus below the surface of the gemstone.
8 posted on 08/05/2008 12:14:21 PM PDT by DocRock (All they that TAKE the sword shall perish with the sword. Matthew 26:52 Gun grabbers beware.)
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To: neverdem
Petran-Hadravsky
Google

9 posted on 08/05/2008 12:36:16 PM PDT by SunkenCiv (https://secure.freerepublic.com/donate/_______Profile hasn't been updated since Friday, May 30, 2008)
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To: DocRock

Good question. I have no idea.

But it sounds like something you could use!

Me, I’m waiting for them to invent Mt-Palomar-in-Your-Pocket ™, $1.89.


10 posted on 08/05/2008 12:50:41 PM PDT by LibWhacker
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To: DocRock

I carry a 10X eyepiece around at work (electronics assembly). This would be really handy if combined with a good LCD screen and went to substantially higher magnification.


11 posted on 08/05/2008 1:00:16 PM PDT by Liberty1970
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To: LibWhacker
Me, I’m waiting for them to invent Mt-Palomar-in-Your-Pocket ™, $1.89.

Is that a telescope in your pocket or have are you just happily looking at Heavenly Bodies?

Cheers!

12 posted on 08/05/2008 9:05:15 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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