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!!!NIH Halts Study on Naproxen!!! (Aleve Ingredient)
washingtonpost.com ^ | Tuesday, December 21, 2004 | Rick Weiss

Posted on 12/20/2004 7:29:28 PM PST by crushelits

Another Painkiller Linked to Heart Risk

NIH Halts Study On Aleve Ingredient

The epidemic of bad news about the potential risks of popular anti-inflammatory medications expanded yesterday as federal officials announced that naproxen, a painkiller sold by prescription and also over the counter as Aleve, might increase people's risk of having a heart attack or stroke.

<> The new findings bring to three the number of widely used anti-inflammatory drugs suddenly in the spotlight for their potential health risks. Vioxx was pulled from the market this fall, and its sister drug Celebrex, the blockbuster arthritis drug, was linked to heart attacks and strokes last week, stopping a major clinical trial.Researchers uncovered the potential problem with naproxen on Friday during a quick review of data from a large, ongoing three-year-old National Institutes of Health study. As part of that study, which has aimed to see if anti-inflammatory drugs can help delay the onset of Alzheimer's disease, 2,500 elderly people have been receiving regular doses of naproxen or Celebrex.

The Alzheimer's study review, triggered by Celebrex's recent woes, surprised officials by revealing a 50 percent increase in heart attacks or strokes among study participants taking naproxen compared with those who had been taking placebos. There were no apparent increases in those life-threatening events among those taking Celebrex -- a reassuring if somewhat confusing finding in light of other evidence to the contrary.

(Excerpt) Read more at washingtonpost.com ...


TOPICS: Health/Medicine
KEYWORDS: acetominifen; aleve; aspirin; atkins; fda; halts; health; ibuprofen; naproxen; nih; study

1 posted on 12/20/2004 7:29:28 PM PST by crushelits
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To: crushelits

The studies fail to tell you that most of the participants also ate broccoli in large amounts.


2 posted on 12/20/2004 7:31:49 PM PST by Salvey
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To: crushelits

Oh well. there is always codeine. Ironic isn't it, that the paranoia of narcotics that actually DO relieve pain, led to the proliferation of all these drugs that are for the most part innefective against pain, and are turning out to have negative cardio-vascular effect.


3 posted on 12/20/2004 7:32:21 PM PST by L`enn
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To: crushelits

Naproxen has been on the market for a long long time, perhaps 20 to 30 years or even longer under the brand name Naprosyn.

How in the sam hell can a product be around for that long, and nobody notice a 50% increase in heart problems?

Perhaps the new studies used elevated strengths over what was the normal doseage over the years.


4 posted on 12/20/2004 7:34:29 PM PST by DoughtyOne (US socialist liberalism would be dead without the help of politicians who claim to be conservat)
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To: crushelits

BTW, I guess this could be the silver lining, but those who died of Heart Failure and Strokes were probably mostly Alsheimers free. Groan...


5 posted on 12/20/2004 7:36:55 PM PST by DoughtyOne (US socialist liberalism would be dead without the help of politicians who claim to be conservat)
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To: crushelits

Luckily I don't take any OTC meds every day, just every once in a while (and no prescriptions). One of those is Aleve, which works like a charm, and for a long time (most of the waking day). Ibuprofen chews up my stomach.


6 posted on 12/20/2004 11:38:51 PM PST by SunkenCiv ("All I have seen teaches me trust the Creator for all I have not seen." -- Emerson)
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To: SunkenCiv

For an anti-inflamatory, I use a health food product - Bromelain. Less expensive, no side effects, and it works.


7 posted on 12/21/2004 8:58:02 AM PST by aimhigh
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