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Review of More Than 120 Studies Finds Scant Evidence of Benefit for Medical Cannabis
Epoch Times ^ | 12/16/2025 | Zachary Stieber

Posted on 12/16/2025 10:13:29 AM PST by SeekAndFind

A new review of more than 120 studies concluded that there is little evidence supporting the use of medical cannabis for a variety of conditions, including insomnia.

The U.S. Food and Drug Administration has approved cannabinoids, a chemical compound extracted from cannabis, for chemotherapy-induced nausea and vomiting and seizures, among other conditions. Many patients use cannabinoids or other medical cannabis for other conditions, such as anorexia, insomnia, and chronic pain, either through off-label prescriptions or through state availability.

A look at research published from January 2010 through September, though, showed that for many conditions, “evidence is insufficient,” researchers with the University of California, Los Angeles (UCLA) and other institutions said in the review, which was published Nov. 26 by the Journal of the American Medical Association.

The evidence base featured more than 120 studies, including some randomized. placebo-controlled clinical trials.

“While many people turn to cannabis seeking relief, our review highlights significant gaps between public perception and scientific evidence regarding its effectiveness for most medical conditions,” Dr. Michael Hsu, one of the authors and a health sciences clinical instructor at the UCLA Health Department of Psychiatry and Biobehavioral Sciences, said in a statement. “Clear guidance from clinicians is essential to support safe, evidence-based decision-making when discussing medical cannabis with their patients.”

He also said, “Patients deserve honest conversations about what the science does and doesn’t tell us about medical cannabis.”

At the same time, the products can lead to problems such as dry mouth, diarrhea, and dizziness, and long-term health outcomes are still being studied.

There is evidence supporting treating certain conditions, such as nausea and vomiting, with medical cannabis or cannabinoids, the researchers said. Limitations of the research included not covering the risk of bias for the studies that were analyzed, and some of the studies analyzed for the review being observational.

“Further research is crucial to better understand the potential benefits and risks of medical cannabis,” Hsu stated. “By supporting more rigorous studies, we can provide clearer guidance and improve clinical care for patients.”

Conflict of interest disclosures included Hsu reporting being on the advisory board for Healthy Gamer, a platform that creates content and provides mental health coaching for youth. The research was supported by the Greater Los Angeles Veterans Affairs Medical Center. The center did not have a role in the design or conduct of the study, or the interpretation of the data, the authors said.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: bravenewworld; cannabis; duh; marijuana; medicine; ofcourse; pot
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To: SaxxonWoods

“some have massive problems with alcohol,”

But we don’t have Soros funding it as a miracle drug.


41 posted on 12/16/2025 12:26:04 PM PST by TexasGator
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To: Jim W N

Yes it’s been proven over and over stoners give finger.

PROOF


42 posted on 12/16/2025 12:29:25 PM PST by Vaduz (?.)
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To: normbal
THC takes many multiples of hours for reducing interference with fine motor skills

Boy have I got a story for you. Lol. In the end, I'd rather be on the road with a bunch of stoners who have their eyes on the road, hands at ten & two and every set of headlights in the rear view is a cop, rather than a bunch of drunks who don't & can't care.

43 posted on 12/16/2025 12:55:41 PM PST by dware (Americans prefer peaceful slavery over dangerous freedom)
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To: gundog

Well, I’m a child of the Sixties so I smoked the gange for years. I have nothing against it and it has some benefits. The only reason I quit smoking it was because it was making me gain weight with the appetite enhancement. Its fine with me if they legalize it.


44 posted on 12/16/2025 1:19:36 PM PST by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Georgia Girl 2
It was age that made you gain weight. Ban aging! 😃 And more Doritos, please.

I remember telling a high school teacher that it would be legal, and taxed, at some point. I didn’t foresee that I’d have lost interest in it, by then.

45 posted on 12/16/2025 1:28:36 PM PST by gundog (The ends justify the mean tweets. )
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To: SeekAndFind

I was telling people this fact here years ago. Medical MJ has always been a crock of hogwash and an excuse to legally get high.


46 posted on 12/16/2025 1:32:40 PM PST by Bullish (My tagline ran off with another man, but it's okay... I wasn't married to it.)
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To: dware

Dude, you have some serious language comprehension issues probably due to the THC. Try to recall, I did say impaired is impaired..


47 posted on 12/16/2025 1:54:53 PM PST by normbal (normbal. Non-native Tennessean.)
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To: SeekAndFind

You mean like the clot shot?


48 posted on 12/16/2025 1:59:02 PM PST by 1FreeAmerican
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To: SeekAndFind

Of my limited experience NOTHING has worked better for my migraines like a puff or two from a THC vape pen. At the first sign of a migraine (flashes of light, blindness, etc.) a puff stops it in minutes.


49 posted on 12/16/2025 2:51:15 PM PST by Organic Panic ('Was I molested. I think so' - Ashley Biden in response to her father joining her in the shower)
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To: dware

I just posted nothing has stopped an oncoming migraine attack like pot. I get the flashes and lose sight in one eye before it happens. If I get a hit in time it compeletely stops it in minutes. If I don’t, I am laid up for a day or two. I know epileptics who get signs of an attack coming up too. CBD has been tested and approved to treat epilepsy in children. You don’t get high with CBD.

I will take my chances with a vape pen over some of the drugs used to treat migraines. The potential side effects are worse than the migraine.


50 posted on 12/16/2025 2:56:35 PM PST by Organic Panic ('Was I molested. I think so' - Ashley Biden in response to her father joining her in the shower)
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To: SeekAndFind
Bombshell Cannabis Study Reveals Hidden Risks of Medical Pot That May Actually Outweigh Any Benefits

12/13/2025 1:01:45 PM PST · by nickcarraway · 93 replies New York Post ^ | Dec. 13, 2025 | McKenzie Beard

https://freerepublic.com/focus/f-news/4357254/posts

51 posted on 12/16/2025 3:34:35 PM PST by Paal Gulli
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To: SeekAndFind

The higher the pain level the higher the anxiety is for the patient waiting for his next pain killer dose, usually an opiate. The anxiety will intensify the sensation of pain. THC in weed decreases anxiety and thus has valid medical use. It does nothing directly to reduce pain.


52 posted on 12/16/2025 8:39:08 PM PST by cpdiii (cane cutter, deckhand, oilfield roughneck, drilling fluid tech, geologist, pilot, pharmacist, MAGA)
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To: dware

“In the end, I’d rather be on the road with a bunch of stoners who have their eyes on the road, hands at ten & two and every set of headlights in the rear view is a cop, rather than a bunch of drunks who don’t & can’t care.”

ROTFLMAO at your description of how stoners drive ...

NO WAY!


53 posted on 12/17/2025 9:13:29 AM PST by TexasGator
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To: TexasGator
ROTFLMAO at your description of how stoners drive

I forgot the "5 miles under the limit" part. MJ affects short term memory.

54 posted on 12/17/2025 9:34:34 AM PST by dware (Americans prefer peaceful slavery over dangerous freedom)
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