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Your Spouse Started Antidepressants and Became a Stranger
Brownstone Institute ^ | August 12, 2025 | Roger McFillin

Posted on 08/12/2025 6:41:26 AM PDT by Heartlander

Your Spouse Started Antidepressants and Became a Stranger

I don’t know who this person is anymore,” James told me, his voice cracking as he described his wife of fifteen years. “She started Zoloft eight months ago for some mild anxiety about work. Now she’s rewritten our entire history together. According to her new narrative, I’ve been emotionally abusive for years. She’s filed for divorce, moved in with some guy she met at a yoga retreat, and told our kids that daddy was never really there for them.”

He paused, searching for words. “The strangest part? She seems completely unbothered by destroying our family. It’s like she’s watching it happen from outside her own body.”

Welcome to the SSRI marriage apocalypse: a phenomenon so widespread that entire online communities have formed to support its casualties. Spouses gathering in digital refugee camps, comparing notes about partners who transformed into unrecognizable strangers after starting antidepressants. The stories are eerily similar: personality changes, moral compass spinning wildly, empathy evaporating, sexual connection obliterated, and a strange, detached willingness to torch everything they once held sacred.

But here’s what makes my blood boil: The mental health establishment celebrates these relationship demolitions as therapeutic breakthroughs. “The medication lifted their mood enough to finally leave that toxic relationship!” they’ll proclaim, completely ignoring that the “toxicity” might be a drug-induced fabrication. This is my fundamental criticism of the therapy industry: therapists attach to their client’s inner world as if it’s absolute fact, unquestionable truth. 

Even without SSRIs, people alter reality and create stories to cope with pain. But add psychiatric drugs to the mix, and you’ve got modern therapists providing unfettered validation to chemically distorted narratives, rarely approaching cases with empirical scrutiny. They jump right on the victim mindset, and in many cases, actively create it. “Yes, you were trapped in an abusive marriage!” they’ll affirm to someone whose brain chemistry has been so altered they couldn’t recognize genuine love if it slapped them in the face.

The Spell-Binding Effect 

Dr. Peter Breggin, Harvard-trained psychiatrist and former consultant to the National Institute of Mental Health, who’s spent decades exposing the dark underbelly of his own profession, called it “medication spellbinding:” the insidious way psychiatric drugs prevent users from recognizing their own drug-induced dysfunction. (I’m actually traveling to Dr. Breggin’s home next week to interview him, and you can bet your ass I’ll be drilling deep into this spellbinding phenomenon.) It’s not just that SSRIs change you; they rob you of the ability to perceive that you’ve been changed. You become a stranger to yourself while believing you’re finally seeing clearly.

“Lisa” sat across from me six months after stopping Lexapro, tears streaming down her face. “I feel like I’m waking up from a nightmare I created. I had an affair. I told my husband of twenty years that I’d never really loved him. I was prepared to walk away from my children without a second thought. Now I look back and think, ‘Who was that person?’ But at the time, it all made perfect sense. I felt nothing. No guilt, no remorse, no connection to my old life. It was like living in emotional Novocain.”

This is your brain on SSRIs: chemically castrated, not just sexually but emotionally, morally, spiritually. The same serotonergic manipulation that’s supposed to lift your mood also severs the invisible threads connecting you to everything that matters. But you won’t realize it’s happening because the drug disables your ability to recognize its own effects.

The psychiatric establishment has convinced millions that flooding the brain with serotonin is as benign as taking vitamin C. They’ve never bothered to mention that serotonin doesn’t just regulate mood; it shapes moral reasoning, empathy, pair bonding, sexual response, and the entire constellation of neurochemical processes that make us capable of authentic human connection. 

This is why I have profound concerns about prescribing these drugs during critical developmental periods. When you chemically alter serotonin in a developing adolescent brain, you’re not just tweaking mood; you’re potentially rewiring their capacity for intimacy, identity formation, and even sexual orientation. The explosion of gender dysphoria cases perfectly paralleling the mass prescribing of SSRIs to teenagers? That’s not a coincidence worth ignoring. That’s a red flag the size of Texas that nobody wants to acknowledge because it threatens both Big Pharma profits and progressive orthodoxy.

When “Treatment” Becomes Home-Wrecking

Here’s what the hundreds of stories flooding my inbox and online communities reveal: SSRIs create a spectrum of personality destruction, and we’re essentially playing Russian roulette with human consciousness. The response varies wildly because we’re experimenting with pharmaceutical compounds that fundamentally alter human nature itself.

For some, there’s an almost immediate activation syndrome (conveniently buried in the clinical trial data). Within days or weeks, they experience impulsivity that would make a teenager blush. Reckless spending, sexual promiscuity, acting without any consideration of consequences. One woman described it perfectly: “It was like someone disconnected the brake pedal in my brain. I was all accelerator, no caution.” Affairs happen in this state. Life-destroying decisions get made. Families implode while the person feels euphoric about the destruction.

For others, it’s the slow slide into emotional death. The detachment creeps in gradually: first, colors seem less vibrant. Music loses its emotional pull. Then comes the relationship anesthesia. “I just don’t feel anything for him anymore” becomes the refrain, as if discussing a roommate rather than a life partner. The sexual dysfunction arrives not just as decreased libido but complete genital numbness, the physical capacity for intimate bonding chemically severed. But instead of recognizing this as drug-induced castration, it gets reframed: “I guess I was never really attracted to them.”

The empathy erosion is perhaps the most chilling. The person who once cried at commercials now watches their partner’s pain with scientific detachment. Children become logistical problems to solve. Love transforms into a word they remember but can’t feel. It’s not cruelty; it’s worse. It’s the presence of absence where humanity used to live.

The therapy industrial complex, thoroughly indoctrinated in the chemical imbalance mythology, validates every drug-distorted thought. Your couples therapist, who hasn’t bothered to research SSRIs beyond pharmaceutical marketing materials, encourages your drugged spouse to “trust their feelings” and “honor their truth,” never once considering that their feelings are chemically manufactured and their truth is pharmaceutical fiction.

Post SSRI Sexual Dysfunction (PSSD)

Post-SSRI Sexual Dysfunction (PSSD) is the dirty secret of psychiatry that could bring down the entire house of cards if people truly understood its implications. We’re not talking about temporary side effects here. We’re talking about permanent sexual castration that persists, even after stopping the drugs.

But PSSD isn’t just about sex. It’s about the complete severing of the embodied experience of human connection. The neurochemical pathways that create sexual arousal are the same ones involved in emotional bonding, passionate engagement with life, and the felt sense of love itself. When SSRIs nuke these systems, they don’t just steal orgasms; they steal the capacity for embodied intimacy altogether.

And now we have hard scientific evidence for what these communities have been screaming into the void. A 2019 study published in Translational Psychiatry by Rütgen and colleagues finally confirmed what Big Pharma has desperately tried to suppress: SSRIs don’t improve empathy in depression; they systematically destroy it.

The researchers found that after just three months of antidepressant treatment, patients showed significant decreases in both emotional empathy and brain activity in regions crucial for empathic responding. The more their depression “improved,” the less they could feel others’ pain. They literally measured the chemical assassination of human compassion.

But here’s what nobody wants to admit: the pharmaceutical industry measures “improvement” in depression by how much less you feel. Can’t cry at your mother’s funeral? Success! Don’t feel devastated when your child is hurting? Treatment is working! Unable to empathize with your spouse’s pain? Congratulations, your depression is in remission! They’ve redefined mental health as emotional lobotomy and convinced us to celebrate our numbness as recovery.

Think about what this means for marriages: Your depressed spouse starts SSRIs, and within months, they’re neurologically incapable of feeling your emotional pain. The researchers called this a “protective function,” but let’s call it what it really is: chemically-induced sociopathy. The study showed decreased connectivity between brain regions responsible for emotional and cognitive empathy. Translation: the drug literally disconnects the wiring that allows us to feel for each other.

The Anti-Human Agenda 

Let’s call this what it is: an anti-human movement masquerading as mental health care. When you create drugs that systematically disable the neurochemical foundations of human bonding, empathy, and moral reasoning, you’re not treating illness; you’re engineering the dissolution of the social fabric itself.

But SSRIs are just one weapon in a much larger war against human flourishing. Look around: We’re poisoning masculinity as “toxic,” redefining female hormonal cycles as psychiatric disorders, and severing our children from nature itself, replacing dirt, sunlight, and real play with screens and synthetic environments. We’re feeding them processed poison disguised as food, then wondering why their bodies and minds rebel. We’re replacing human connection with digital interfaces, substituting virtual “friends” for real relationships, and celebrating isolation as “self-care.” Every institution that once fostered genuine human bonds (family, community, spiritual fellowship) is under systematic attack.

The gender confusion epidemic perfectly paralleling mass SSRI prescribing to adolescents? The explosion of young people who suddenly can’t recognize their own bodies, can’t connect to their biological reality? When you chemically sever a developing mind from its capacity to feel authentic connection to self and others, is it any wonder they become strangers in their own skin?

This anti-human agenda operates through multiple vectors: Seed oils inflaming our brains, endocrine disruptors scrambling our hormones, screens hijacking our attention, pornography replacing intimacy, and yes, psychiatric drugs severing our souls. Each element reinforces the others, creating a perfect storm of disconnection. The SSRIs ensure you won’t feel the horror of what’s being done to you. They’re the anesthesia for the operation that’s removing our humanity.

Every marriage destroyed by SSRI-induced apathy, every parent who stops feeling love for their children, every affair justified by chemically-induced emotional numbness: these aren’t unfortunate side effects. They’re features, not bugs, of a system designed to atomize human connection and create perpetual patients.

The online communities tracking this phenomenon aren’t conspiracy theorists or anti-medication extremists. They’re regular people sharing strikingly similar stories: My spouse started antidepressants and became someone else. They lost the ability to feel love. They rewrote our history. They destroyed our family with cold efficiency. And when they finally stopped the drugs (if they stopped) they woke up horrified at what they’d done.

One woman in these forums wrote something that haunts me: “The drug didn’t just steal my husband. It stole the person he was during our children’s most formative years. Even though he’s himself again now, off the drugs, our kids don’t know who he really is. They only know the emotionally absent stranger who lived in our house for three years.”

The Revolution We Need

The psychiatric establishment won’t save us from this; they created it. The therapists validating drug-distorted realities won’t help; they’re complicit. The only solution is brutal honesty about what these drugs actually do to human consciousness and connection.

If you’re on SSRIs and your marriage is falling apart, consider this: Maybe it’s not your marriage that’s broken. Maybe it’s your capacity to feel it.

If your partner started antidepressants and became a stranger, you’re not imagining it. You’re witnessing a chemically induced personality transplant.

If you’re a therapist reading this and getting defensive, ask yourself: How many marriages have you helped validate into destruction because you couldn’t question the sacred cow of psychiatric medication?

We need to stop pretending that chemically altering the foundation of human emotion and connection is neutral. We need to stop acting like SSRIs are precision instruments when they’re actually neurochemical sledgehammers. We need to acknowledge that when you interfere with serotonin, you’re not just adjusting mood; you’re rewiring the capacity for love itself.

The families destroyed by SSRIs aren’t collateral damage; they’re casualties of an undeclared chemical war on human connection. And until we’re willing to name this war and fight back, the casualties will keep mounting, one numbed-out divorce at a time.

Your depression might be real. Your anxiety might be valid. Hell, in this toxic wasteland of a culture we’ve created, feeling depressed and anxious might be the only sane response. But look at how we’ve been programmed to address these legitimate feelings: Rush to the doctor. Get the diagnosis. Take the pill. Never once questioning whether numbing the pain is the same as healing it. 

We’ve been brainwashed to believe that feeling less is the same as feeling better, that chemical numbness equals mental health. But is addressing your struggle this way worth sacrificing your capacity to love and be loved? Is it worth becoming a stranger to yourself and everyone who matters to you? Is a life without authentic emotional connection really better than a life with difficult emotions?

This more than a medical question. It’s a spiritual one. And the answer might just save your marriage and your soul. 

RESIST


TOPICS:
KEYWORDS: mgtow; pua; redpill; ssri; women
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To: rod5591

“”Ain’t psychiatrists and psychologists great!””

In a family member’s case, it was neither - it was a Neurologist! Started with one med and over the years, one med piled on top of another and another and another until that person is unrecognizable.


41 posted on 08/12/2025 7:38:10 AM PDT by Thank You Rush
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To: Georgia Girl 2
"She's ready to get out, ssri's just gave her the push"

bingo! Ssri's take away any thoughts of others feelings, no empathy, you want to feel better NOW, and screw your spouse AND any small children's lives.

42 posted on 08/12/2025 7:39:39 AM PDT by Ikeon (Help a man today, and tomorrow he will get into trouble on purpose, because youll help him.)
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To: Heartlander

Years and years ago, I went through this. I was being treated for depression, but I didn’t consider myself particularly depressed, just going through a rough patch. I was put on Zoloft.

It made me feel like a zombie. No highs, no lows. I couldn’t feel joy anymore, but I didn’t cry either. Some people think that’s being steady, but for me, it was like I wasn’t alive, just going through the motions.

I had several issues that I was legitimately working through, which I won’t go into here, and I did need treatment for that. Talking with my doctor took time, but I eventually got it sorted out with his help. Unfortunately, that included years of me being medicated with Zoloft.

When I told him I no longer wanted to be on the medication, he had to taper me off of it. Every time I dosed down, I was a raving bitch maniac on day 2 and day 3. I have a gem of a husband who knew I was truly on the path of being healed, so he put up with those awful days, that happened every 3 months for two years. Two years! Let that sink in! It took two whole years of tapering off that damn SSRI to finally be free of it.

I’m so happy that I am off of those terrible drugs. I think they hand them out like candy, but they are very dangerous.


43 posted on 08/12/2025 7:40:07 AM PDT by FamiliarFace (I got my own way of livin' But everything gets done With a southern accent Where I come from. TPetty)
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To: Heartlander

My gal can go from a princess to a total witch just by missing one day without her pill.


44 posted on 08/12/2025 7:40:34 AM PDT by South Dakota (Vance / Trump...2028 )
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To: Tuxedo

27 years for mine. I now have 28 with a wonderful woman. Was a nightmare when it happened.


45 posted on 08/12/2025 7:46:53 AM PDT by KC Burke
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To: Ikeon

Mushroom spores are legal and readily available over the internet. Personally I ignore stupid laws anyway. Last time I checked IV ketamine ( the most effective way of administering it) was rarely covered by insurance. To get a script for Esketamine (intranasal) you have to show you’ve tried all the cheaper antidepressants first and it’s not as effective as IV administration from what I’ve heard.


46 posted on 08/12/2025 7:53:08 AM PDT by jimwatx
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To: fwdude

Incredible story....thank you for being his advocate.

There are some people in the elder generation who feel that they didn’t get their monies worth from a doctor visit unless the leave with a new, additional prescription. And of course the barrage of direct to patient pitched commercials on TV does not help that situation!


47 posted on 08/12/2025 8:01:03 AM PDT by lightman (Beat the Philly fraud machine the Amish did onest, ja? Nein, zweimal they did already!)
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To: heartwood

That took guts on this thread


48 posted on 08/12/2025 8:04:51 AM PDT by sopo
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To: T.B. Yoits

The medical industry never stopped performing lobotomies. They switched to chemical ones.


49 posted on 08/12/2025 8:25:40 AM PDT by T.B. Yoits
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To: Nea Wood

Ping for later


50 posted on 08/12/2025 8:39:37 AM PDT by Nea Wood ( )
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To: Heartlander

If the mass murderers were checked out, they would find most were on anti-depressants. Columbine for example and others, but no one addresses this.

Very sad.


51 posted on 08/12/2025 8:49:05 AM PDT by sweetiepiezer (WINNING is not getting old!!! ❤️USA❤️)
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To: Heartlander

I have a female friend who married a man totally unaware of his lifelong struggle with depression. He obviously did a damned good job of concealing it during their courtship. The mask came off after the wedding, though. She lived a hellish existence for a while, before getting him on different meds and proclaiming him “cured.” I’m pretty damned skeptical of that, tbh. I pray for them (and their kid).


52 posted on 08/12/2025 8:55:34 AM PDT by irishjuggler
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To: Heartlander

Souma Yergon, Sou Nou Yergon
We are shakin’ the tree
Souma Yergon, Sou Nou Yergon
We are shakin’ the tree
Waiting your time, dreaming of a better life
Waiting your time, you’re more than just a wife
You don’t have to do what your mother has done
She has done, this is your life, this new life has begun
It’s your day, a woman’s day
It’s your day, a woman’s day


53 posted on 08/12/2025 9:04:44 AM PDT by aspasia
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To: Heartlander
She started Zoloft eight months ago for some mild anxiety about work.

What happened that we somehow think anxiety is something that should be treated with medication?

Anxiety is normal when you are under stress. You should have started to learn to deal with it sometime about age six or seven.

Medication is for real problems. Not, oh I have three reports to fill out today. You work for the bomb squad you may end up with anxiety that needs medical treatment.

Most people do not.

54 posted on 08/12/2025 9:07:27 AM PDT by Harmless Teddy Bear ( Not my circus. Not my monkeys. But I can pick out the clowns at 100 yards.)
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To: Thank You Rush

I have 3 family members whose lives were ruined by SSRIs. Only one was able to get off them and rebuild their life.


55 posted on 08/12/2025 9:45:19 AM PDT by CaptainK ("No matter how cynical you get, it is impossible to keep up” )
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To: Heartlander

Oh no...thank you for posting this.


56 posted on 08/12/2025 10:03:06 AM PDT by subterfuge (I'm a pure-blood!)
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To: rod5591

And GPs! My wife went in for a check-up and she was going through a rough patch (her ex, a child molester, was getting released). The GP asked her two questions: if she was depressed and had suicidal thoughts (”yes” and “sometimes I guess” were the answers). BAM! Instant prescriptions to “anti-depressants”. She became physically and emotionally abusive. She committed several, let’s say, “high risk” behaviors. Then came the painkillers: oxy and lortab.

I talked to my docs, I did my research, and I got her off the pills (used to work in an addiction clinic, and I treated her like she had a heroin addiction). Got her off everything in three weeks and she never went back on that crap.

In this day and age, ANY doctor can prescribe anything at any time for any reason. And I hate them for exercising that ability for their own desires and to hell with everyone else.


57 posted on 08/12/2025 10:57:00 AM PDT by Retrofitted
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To: jimwatx
Personally I ignore stupid laws anyway

😬🙄 You need drugs.

58 posted on 08/12/2025 11:01:56 AM PDT by Ikeon (Help a man today, and tomorrow he will get into trouble on purpose, because youll help him.)
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To: Ikeon

That’s true. As a matter of fact I think I will start the process of growing some psilocybin mushrooms today especially now that’s there’s evidence it prolongs lifespan.

Psilocybin delays aging, extends lifespan, new Emory study suggests
https://news.emory.edu/stories/2025/07/hs_psilocybin_aging_study_10-07-2025/story.html


59 posted on 08/12/2025 11:13:32 AM PDT by jimwatx
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To: Harmless Teddy Bear

At one time the Pharma/Shrink complex was pushing a completely false narrative that you could have depression without symptoms. Let that sink in.

Read the DSM4 sometimes for a good laugh. My favorite Disorders: drinks too much coffee, can’t do math, disagrees with the shrink’s diagnosis. That last one is very obviously insane. In many jurisdictions you can be involuntarily institutionalized for these disorders.


60 posted on 08/12/2025 11:15:16 AM PDT by Seruzawa ("The Political left is the Garden of Eden of incompetence" - Marx the Smarter (Groucho))
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