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Higher dose of melatonin improved sleep in older adults (5 mg taken for 2 weeks = “Significant increase in total sleep time and sleep efficiency)
Medical Xpress / Harvard University / Journal of Pineal Research ^ | May 19, 2022 | Jeanne F. Duffy et al

Posted on 05/19/2022 9:09:45 AM PDT by ConservativeMind

In a small study of healthy adults aged 55 and older, 5 mg of melatonin increased total sleep time compared to a placebo.

Researchers conducted the study in 24 healthy, older adults to evaluate whether a high-dose or a low-dose melatonin supplement could improve sleep. The team found that the higher dose had a significant impact, increasing total sleep time compared to placebo by more than 15 minutes for nighttime sleep and by half an hour for daytime sleep.

The body naturally produces melatonin, which helps regulate a person's sleep-wake cycle with night and day. Melatonin levels peak at night. But among older people, levels of the hormone are often lower. Exogenous melatonin is sold over the counter and can be taken before bedtime as a dietary supplement, usually in a pill.

During the monthlong study period, participants lived in individual study rooms with no windows, clocks, or other indications of time of day. Participants followed a forced desynchrony protocol—instead of experiencing 24-hour cycles of days and nights, they were on schedules of 20-hour cycles to disentangle the effects of rest-activity from the circadian clock. Participants were randomly assigned to receive two weeks of a placebo pill and two weeks of either a low (0.3 mg) or high (5 mg) dose of melatonin 30 minutes before bedtime. Researchers used polysomnography to record brain waves, eye movement, muscle tone, and other key sleep metrics.

The team found that the low dose of melatonin did not lead to a statistically significant change in overall sleep time and that the changes that were seen were when sleep was scheduled during the biological day. Participants taking the 5 mg dose had a significant increase in total sleep time and sleep efficiency regardless of whether sleep was scheduled during the day or night.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: melatonin; sleep; supplement
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To: SheepWhisperer; All

“It’s quite amazing how many sleep with a teevee on all night in the bedroom and complain they don’t sleep well!”

I have never had a TV in the bedroom, for all the reasons you stated. I LOVE to sleep and I’m good at it! It’s sometimes the best part of the day!

Glad to see I’m not the only one that has had a bad reaction to melatonin. I’m also equally glad that it’s working well for others. :)


41 posted on 05/19/2022 12:52:38 PM PDT by Diana in Wisconsin (I don't have, 'Hobbies.' I'm developing a robust Post-Apocalyptic skill set. )
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To: PeterPrinciple

The low dose was too little to impact the results in any way.

The high dose, was enough, with its results.


42 posted on 05/19/2022 12:52:53 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: MomwithHope

I’m glad it works for you! It gives me the heebie-geebies! ;)


43 posted on 05/19/2022 1:11:24 PM PDT by Diana in Wisconsin (I don't have, 'Hobbies.' I'm developing a robust Post-Apocalyptic skill set. )
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To: steve86

https://lifespa.com/ayurvedic-lifestyle/circadian-rhythm/sun-exposure-melatonin/


44 posted on 05/19/2022 2:06:58 PM PDT by Sacajaweau ( )
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To: ConservativeMind

Eh, I’ve tried it.

I don’t sleep any better and just feel groggier in the morning.


45 posted on 05/19/2022 2:31:47 PM PDT by martin_fierro (< |:)~)
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To: refreshed; Diana in Wisconsin; All

The herb Valerian can help reduce anxiety. I sometimes can’t sleep worrying about all I need to do, and Valerian helps with that. Sometimes I am just keyed up from an active day and melatonin helps with that. I seem to recall reading something about Vitamin B6 and vivid dreams. I don’t remember if it was too much or not enough.


46 posted on 05/19/2022 2:38:02 PM PDT by gleeaikin (Question authority)
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To: Sacajaweau

...during the day


47 posted on 05/19/2022 3:01:09 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: ConservativeMind

No friggen way I could participate in that study !

I take 15 mg melatonin every nite.


48 posted on 05/19/2022 6:24:48 PM PDT by Delta 21 (It started as a virus, and mutated into an IQ test.)
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To: WHATNEXT?

The scopalomine sea-sick patches would give me full blown hallucinations. 1st crazy dreams, then hallucinated dreams, then just tripping out twice a day. That would have been a fun week if we hadn’t of been in 30’ seas off Nova Scotia in January.


49 posted on 05/19/2022 6:36:59 PM PDT by Delta 21 (It started as a virus, and mutated into an IQ test.)
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To: SheepWhisperer

For a few dollars, blue-wavelength-blocking googles can be purchased.

I sometimes wear them in the evening before I’m ready to turn out the lights.

Amber/Red light bulbs (think i a submarine) can also be purchased for evening use.


50 posted on 05/19/2022 7:24:35 PM PDT by YogicCowboy (I know what I like, and like what I know.)
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To: SheepWhisperer

Bookmark for later


51 posted on 05/20/2022 8:52:06 AM PDT by Irish Eyes
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To: Delta 21

I had tried most things for seasickness. I was in Hawaii sitting on a bench on land, waiting to get on a glass bottom boat, when I began to feel seasick. I went on the boat, off the back into the water, like the rest of the people AND CHUMMED THE FISH. The fish loved me...gross I know. The effects lasted two days.

Have found that Motion Mate (mainly ginger) will let me do water things...with care.


52 posted on 05/20/2022 2:18:35 PM PDT by WHATNEXT?
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To: WHATNEXT?

Scopolamine is a wonder drug for me.

Melatonin works for me, too, but I don’t take it regularly. I don’t want to build up a tolerance.


53 posted on 05/20/2022 10:29:49 PM PDT by Reddy ( B.O. stinks)
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To: WHATNEXT?

Wait, all that happened after you used scopolamine? Definitely not as advertised for you lol.


54 posted on 05/20/2022 10:34:33 PM PDT by Reddy ( B.O. stinks)
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To: YogicCowboy
I sometimes wear them in the evening before I’m ready to turn out the lights.

You are clearly a big giant dork.

55 posted on 05/21/2022 7:41:46 PM PDT by humblegunner (Ain't drownin', Just wavin'...)
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