Posted on 08/30/2021 10:15:37 AM PDT by Red Badger
SCIENCEALERT STAFF Ivermectin is the active ingredient in many widely available anti-parasite medications used to treat infections of worms, scabies, and lice in humans and livestock.
Recently, it has gained popularity in some parts of the world as a potential COVID-19 treatment, despite a lack of scientific evidence for its benefits, and a substantial risk of harmful overdoses.
How does ivermectin work? Ivermectin was developed from a species of Streptomyces bacterium found in the 1970s, the finding was a huge win for the livestock industry and for fighting numerous devastating illnesses around the world, eventually earning the researchers a Nobel Prize.
Ivermectin and its family of parasite-fighting compounds act selectively on a kind of chloride channel only found in invertebrates.
While this makes it a relatively safe drug for knocking out any creepy-crawlies in the body, it is possible to have a toxic reaction or overdose of this medication. At higher concentrations, ivermectin can interact with similar channels in vertebrates like us, interfering with nervous impulses and muscle control.
Can ivermectin treat COVID-19? Over the past 50 years, researchers have found that ivermectin may have other interactions in the human body apart from just tackling parasites.
There have even been signs that ivermectin has antiviral effects in the lab on RNA viruses such as Zika, Hendra, and HIV1, however trials in animal models have been spotty to date.
Since ivermectin already had FDA approval for treating parasites, it seemed like a perfect candidate to test against the SARS-CoV-2 virus – as a potential medication that might limit viral replication in the human body.
Early in 2020, a laboratory study on cell cultures concluded that a single treatment could cause a 5,000-fold reduction in virus particle numbers within just two days. However, this is vastly different from actually using the drug in people.
Several influential studies on the potential benefit of ivermectin as a COVID-19 treatment have resulted in controversy, with independent researchers uncovering substantial scientific fraud in preprint papers that were widely publicized without having received peer review, but ended up being removed from preprint servers or retracted.
"My sincere opinion is that at least a third of the evidence supporting the use of ivermectin as a COVID-19 therapeutic is not just 'based on shaky data', but consists of studies that may never have happened at all," writes Australian epidemiologist Gideon Meyerowitz-Katz.
The latest evidence from a large clinical trial on several repurposed drugs that might be useful for COVID-19 treatment has shown no benefit for ivermectin. More studies are underway, however.
Despite fraud, controversies, and lackluster evidence, ivermectin has been popularized as a COVID-19 treatment around the world, with a number of medical professionals prescribing ivermectin to patients in the hope it might stave off a more serious infection.
If ivermectin has approval, and doctors are prescribing it, what's the harm? Ivermectin has approval in many government jurisdictions for treating parasitic infections. None have approved it for treating COVID-19, and doing so can be dangerous.
Drug regulators such as the US FDA and Australian TGA have issued strict warnings against treating COVID-19 with ivermectin.
"There's a lot of misinformation around, and you may have heard that it's okay to take large doses of ivermectin. That is wrong," warns the FDA.
If ivermectin does have any antiviral benefits in people, clinical trials are needed to determine precisely what dosage can provide the greatest benefits with the fewest risks, for example. There could be conflicts between medications commonly used to treat advanced cases of COVID-19, which would make either medication ineffective, or worse, cause harm.
Read the full US FDA warning here:
https://www.fda.gov/consumers/consumer-updates/why-you-should-not-use-ivermectin-treat-or-prevent-covid-19
All Explainers are determined by fact-checkers to be correct and relevant at the time of publishing. Text and images may be altered, removed, or added to as an editorial decision to keep information current.
Yeah because ya know when there’s a world wide “pandemic” that’s going to kill 300 billion people one of the first things you do is shut down any discussion of and all access to any drug or treatment that is NOT a highly experimental mrna trial injection and forbid and shame any possible alternative to the injection and no this isn’t at all suspicious behavior so stop thinking and weighing facts and just take the injection that has a high kill rate and basically zero effectiveness against anything besides separating free men from slaves.
Mmmkay??
A ton of reports of good results using Ivermectin including right here on this forum. A hell of a lot more people than you will find in your typical clinical trial.
“Scientific evidence” does not mean reports from patients and their physicians that Ivermectin was responsible for keeping their COVID infection from getting worse or from contacting it. It means studies financed by pharmaceutical companies with government support that they have a very good chance of profiting from. I hope that clears things up.
These are all journal-list.
https://www.sciencealert.com/our-team
If Ivermectin so awesome, how do you explain this 30 year old Texas user?
https://www.sfgate.com/coronavirus/article/caleb-wallace-anti-mask-rally-death-covid-16419641.php
Don’t fool yourselves, despite some signs of efficacy, there is no cure for covid.
“Ivermectin has approval in many government jurisdictions for treating parasitic infections. None have approved it for treating COVID-19, and doing so can be dangerous.”
Seems like a lot of doctors in India should be in trouble, then. Haven’t heard anything to that effect, has anyone else?
Why do these shills use terms like ‘large dose’, massive doses
‘ etc. when the usual takers are taking therapeutic doses? Because these bastards are trying to stop us from using what works instewd of their poison jabs.
Opus?
"I am proud of our track record in both of my clinics and at the jail in particular, where not one single patient of the five hundred plus who have followed our plan of care has been hospitalized, intubated or died."
“There’s a lot of misinformation around, and you may have heard that it’s okay to take large doses of ivermectin. That is wrong,” warns the FDA.
This is a bogus strawman dishonest argument.
What about appropriate doses?
And BTW, the title is a lie since the author gave zero information on how to dose yet claimed he was writing for us all we need to know on Ivermectin. Whast a dutiful little lying ‘journo’ the author is.
“So now if my horse has roundworms I have to schlepp around on the dark web like a criminal.”
I suspect that Tractor Supply and similar places have it, but will advertise they don’t. So you’d need to go in there, convince them you have a horse or two and they’ll sell it to you. Just speculation, but with a try before you go to the black market only to buy apple-flavored vasoline.
But the CDC's own website said this:
Who can take hydroxychloroquine?
Hydroxychloroquine can be prescribed to adults and children of all ages. It can also be safely taken by pregnant women and nursing mothers.
I don't know about you, but if the CDC says pregnant woman and nursing women and kids off all ages can take, I'd say it's pretty safe.
YOU lie.
## The irony is it’s the vaccinated creating new strains.
I had that exact conversation with my doctor a couple of weeks ago. By now, we could know an =amazing= amount of information about the actions of these experimental drugs, their actual efficacy, and potential side effects, but no one in a position to actually gather this information seems to be interested at all. NOTHING about this has even appeared to be slightly in line with the scientific method. If they wanted it, they could have massive amounts of data.
At this point there is so much propaganda out there from both sides, that a reasonable person should just go with his gut and act accordingly.
This is an excellent, recent, scientific review article on ivermectin:
Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19
A.D.Santin,E.Scheim,P.A.McCullough,M.Yagisawa,T.J.Borody
1)
Department of Obstetrics & Gynecology, Yale University School of Medicine, New Haven, CT, USA
2)
US Public Health Service, Inactive Reserve, Blacksburg, VA, USA
3)
Texas A & M College of Medicine, Dallas, TX, USA
4)
Ōmura Satoshi Memorial Institute, Infection Control Research Center, Kitasato University, Tokyo, Japan
5)
Centre for Digestive Diseases, New South Wales, Australia
Available online 3 August 2021.
https://www.sciencedirect.com/science/article/pii/S2052297521000883
# Maybe the reason the dems are so afraid of it is because it kills parasites.
LOL. By Jove I think you’ve got it!
When you try to gently explain and tell certain people NOT to do something, it just makes them want to do it even more because “they’re hiding something it must be a conspiracy etc”. It has got to be insanely frustrating haha
The Drug That Cracked Covid
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