'Breakthrough' Found That Could 'Block Course' of COVID-19 Infection

PJ Media ^ | 05/05/2020 | Victoria Taft

[SeekAndFind]

European researchers have found the antibody that can block the infection by the SARS-CoV-2 virus – aka the Wuhan coronavirus – which is now re-branded COVID-19.

The Daily Mail reports that the antibody, “known as 47D11, targets the deadly virus’s infamous ‘spike protein’, which it uses to hook onto cells and insert its genetic material.”

Researchers say that the virus, depicted as a sphere with spikes, “binds to this protein and prevents it from hooking on – effectively neutralising it.”

The good news is that the antibody attacks the worst part of the virus that creates the respiratory disease in COVID-19.

The Daily Mail says the breakthrough could “alter the course of infection or protect an unfenced person exposed to someone with the virus.”

The European research team identified the antibody from 51 cell lines from mice that had been engineered to carry human genes.

The antibody targets the novel coronavirus that caused the 2003 SARS outbreak, known as SARS-CoV-1.

However, scientists claim that it can also neutralise SARS-CoV-2, which is from the same family of coronaviruses as SARS-CoV-1.

‘This research builds on the work our groups have done in the past on antibodies targeting the SARS-CoV that emerged in 2002/2003,’ said co-lead author Professor Berend-Jan Bosch at Utrecht University.

‘Using this collection of SARS-CoV antibodies, we identified an antibody that also neutralises infection of SARS-CoV-2 in cultured cells.

The virus hooks onto a locking point on human cells to insert its genetic material, makes multiples copies of itself and spreads throughout the body.

[SeekAndFind]

NOTE:

Researchers say not only will the antibody neutralize the virus, but it can be made in the lab, which means it’s not dependent on plasma from people previously infected with the virus.

BUT BUT BUT....We can only hope that this is a genuine breakthrough. Research scientists say that this will not be without risk because injecting people with antibodies can be dangerous.

[Artcore]

Dr Fauci to the rescue to pooh pooh this in 3...2...1!

[SeekAndFind]

RE: Dr Fauci to the rescue to pooh pooh this in 3...2...1!

Dr. Fauci vs. Europe? Not gonna happen.

[ClearCase_guy]

As I understand it, a vaccine stimulates the production of antibodies and thereby provides immunity.

What the article talks about would not be a vaccine per se. It would not stimulate production of antibodies. It would simply be an infusion of antibodies manufactured in a lab.

Would this need to be regularly administered?

[gibsonguy]

Fauci’s mission is to keep Trump from being re-elected.

[Vaduz]

Great news but not for the nay sayer’s who said it would take years to do.

[babble-on]

I found a cure for having money! Fund every startup where a doctor announces he’s found the cure for a major disease.

[Mouton]

Fauci’s mission is to keep Trump from being re-elected.

If not his mission, definitely his cause. Trump sees him as some kind of regulator who harasses and bends productive people to his meddlesome ways. No No says the Fauci types, it is raining out, go find your umbrella before you go. Meanwhile you point out the house is on fire and you must get out now. No no says this type control freak.

Wherever this go back to normal push goes, Fauci will work it like an auditor. Auditors are people who come in after the battle is fought and tell you what you did wrong. In that bunch of reactors, he is the chief dung beetle.

[eastexsteve]

So, just injecting this antibody would sidestep the process of a vaccine having to trigger the immune system in to creating antibodies. If true, you would almost be immediately immune instead of waiting a week to ten days for your body to create the antibodies. Let’s hope this works. And, it works on both SARS-1 and SARS-2.

[Rockingham]

It would be administered to stop ongoing infections. The article does not say how long the antibodies persist at effective levels.

[Normandy]

Bkmrk

[sauropod]

bkmk

[Chaguito]

And how many people have received this treatment for Sars-Cov-1? Sars-Cov-2?

I thought so. And when will it be available for human use? About in time for the next attack of a NEW novel coronavirus, for which the testing has to begin from zero.

This is how one gets funding these days. /cynicism

[conservatism_IS_compassion]

It would be administered to stop ongoing infections. The article does not say how long the antibodies persist at effective levels.

IOW, an effective treatment, not a vaccine. OTOH wouldn’t being exposed to Covid itself stimulate the immune system to create immunity?

If you know your treatment is 100% (well, 99.9%) effective, couldn’t you deliberately infect someone you want to protect and, after a calibrated interval, kill off the infection with your synthetic antibodies - and get a health care worker (or other “essential” worker) who was immune?

Sorta like an "attenuated live virus” vaccination - except the attenuation occurs after its introduction into the patient.

[daniel1212]

Thanks for your diligence in posting these informative articles. However, it appears that we have yet to find a cure for the virus that mutates normal character like “ into “ and ’ into ’ and .” into .”, thus hijacking software to produce what is replicated below:

European researchers have found the antibody that can block the infection by the SARS-CoV-2 virus – aka the Wuhan coronavirus – which is now re-branded COVID-19. The Daily Mail reports that the antibody, “known as 47D11, targets the deadly virus’s infamous ‘spike protein’, which it uses to hook onto cells and insert its genetic material.”Researchers say that the virus, depicted as a sphere with spikes, “binds to this protein and prevents it from hooking on – effectively neutralising it.”The good news is that the antibody attacks the worst part of the virus that creates the respiratory disease in COVID-19.

Researchers have yet to find a vaccine for this virus, however, most FReepers are asymptomatic and reportedly immune to it, and carry on their normal perusing and posting practices, though immigrants wonder if there is something serious to it.

A proposed remedy may be to post the text in this word counter and then copy and paste it from there.

[Grampa Dave]

I found a cure for having money! Fund every startup where a doctor announces he’s found the cure for a major disease.

Then, redo sell orders on a regular basis to protect your gains.

[Rockingham]

The problem is that such an approach would be considered too dangerous for those who most urgently need a vaccine — seniors and those with major chronic health issues. For them, the better course is to have the antibody available as a treatment and to await success as to one of the 120 or so vaccine candidates now being developed.

[conservatism_IS_compassion]

What you say has merit, but IMHO the nurses and docs, etc, would tell you that their comrades are "the ones who most urgently need a vaccine.”

When you think about it, the mask issue needs a “view from outer space” perspective. If you were going to a planet which had oxygen in the atmosphere but the atmosphere had toxicity in it, what would you do to prepare to go there?

You would make a space helmet with an electrically powered gizmo to create a benign, comfortable atmosphere inside it. And that is where we are. With the caveats that you also want

• your own exhaust to be non-toxic as well.
• to handle sneezes as necessary,
• to be comfortable for hours of use at a time.
• to be able to converse normally while wearing it.

• And it has to be cheap enough to market to workers/employers everywhere.

Sounds doable to me. All the “electric gizmo" takes is battery-operated low-pressure blowers for the intake and exhaust filters - piece of cake.

[conservatism_IS_compassion]

What you say has merit, but IMHO the nurses and docs, etc, would tell you that their comrades are "the ones who most urgently need a vaccine.”

When you think about it, the mask issue needs a “view from outer space” perspective. If you were going to a planet which had oxygen in the atmosphere but the atmosphere had toxicity in it, what would you do to prepare to go there?

You would make a space helmet with an electrically powered gizmo to create a benign, comfortable atmosphere inside it. And that is where we are. With the caveats that you also want

• your own exhaust to be non-toxic as well.
• to handle sneezes as necessary,
• to be comfortable for hours of use at a time.
• to be able to converse normally while wearing it.

• And it has to be cheap enough to market to workers/employers everywhere.

Sounds doable to me. All the “electric gizmo" takes is battery-operated low-pressure blowers for the intake and exhaust filters - piece of cake.