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What made humans 'the fat primate'?
phys.org ^ | 06/26/2019 | Robin A. Smith, Duke University

Posted on 06/27/2019 10:54:12 AM PDT by BenLurkin

While other primates have less than 9% body fat, a healthy range for humans is anywhere from 14% to 31%.

Using a technique called ATAC-seq, they scanned each species' genome for differences in how their fat cell DNA is packaged.

Normally most of the DNA within a cell is condensed into coils and loops and tightly wound around proteins, such that only certain DNA regions are loosely packed enough to be accessible to the cellular machinery that turns genes on and off.

The researchers identified roughly 780 DNA regions that were accessible in chimps and macaques, but had become more bunched up in humans. Examining these regions in detail, the team also noticed a recurring snippet of DNA that helps convert fat from one cell type to another.

Not all fat is created equal... Most fat is made up of calorie-storing white fat. It's what makes up the marbling in a steak and builds up around our waistlines.

Specialized fat cells called beige and brown fat, on the other hand, can burn calories rather than store them to generate heat and keep us warm.

One of the reasons we're so fat, the research suggests, … is because the regions of the genome that help turn white fat to brown were essentially locked up...in humans but not in chimps.

Humans, like chimps, need fat to cushion vital organs, insulate us from the cold, and buffer us from starvation. But early humans may have needed to plump up for another reason, the researchers say—as an additional source of energy to fuel our growing, hungry brains.

The human brain uses more energy, pound for pound, than any other tissue. Steering fat cells toward calorie-storing white fat rather than calorie-burning brown fat, the thinking goes, would have given our ancestors a survival advantage.

(Excerpt) Read more at phys.org ...


TOPICS: Health/Medicine
KEYWORDS: fat; sugar
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1 posted on 06/27/2019 10:54:12 AM PDT by BenLurkin
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To: BenLurkin

Beer


2 posted on 06/27/2019 10:55:08 AM PDT by Spruce
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To: BenLurkin

BACON!................


3 posted on 06/27/2019 10:55:55 AM PDT by Red Badger (We are headed for a Civil War. It won't be nice like the last one....................)
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To: BenLurkin

Cheeseburgers.


4 posted on 06/27/2019 10:57:14 AM PDT by libertylover (Democrats hated Lincoln too.)
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To: BenLurkin

Orangutans getting no respect.


5 posted on 06/27/2019 10:57:29 AM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: BenLurkin

6 posted on 06/27/2019 10:57:35 AM PDT by Steely Tom ([Seth Rich] == [the Democrat's John Dean])
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To: BenLurkin

Agrarian results in excess, which we eat and learn how process certain carbs and sugars to produce alcohol.

Also, we love hot dead chicken skin.


7 posted on 06/27/2019 10:58:10 AM PDT by Vendome (I've Gotta Be Me https://www.youtube.com/watch?v=BB0ndRzaz2o)
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To: BenLurkin

Crispr that DNA out of me after i have my next box of fried chicken and an extra large dr pepper.


8 posted on 06/27/2019 10:58:16 AM PDT by SWAMP-C1PHER (HOMO, OECONOMIA, ET CIVITAS.)
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To: BenLurkin
One of the reasons we're so fat,

We no longer have to hunt and gather.......and run for our lives from larger predators.

9 posted on 06/27/2019 10:58:31 AM PDT by Hot Tabasco (I'm in the cleaning business.......I launder money)
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To: BenLurkin

We’re not naturally very fat, it is just our modern lifestyles that make us fat, and those are the product of us using our intelligence to prosper beyond what any other animal could achieve.


10 posted on 06/27/2019 10:59:03 AM PDT by Boogieman
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To: BenLurkin

Monkeys can’t drive to Krispy Kreme.


11 posted on 06/27/2019 11:00:42 AM PDT by GnuThere
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To: BenLurkin

Eating other tasty animals.


12 posted on 06/27/2019 11:01:18 AM PDT by Fido969 (In!)
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To: Boogieman

That makes perfectly good sense, but it’s actually not what the article says.

At least not 100%


13 posted on 06/27/2019 11:01:19 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: BenLurkin

Pasta.


14 posted on 06/27/2019 11:02:06 AM PDT by SJSAMPLE
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To: Hot Tabasco

and...I am human and I AM NOT A PRIMATE! Maybe these people should speak for themselves!


15 posted on 06/27/2019 11:02:31 AM PDT by gr8eman
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To: GnuThere
Monkey see monkey do...


"This is your pilot speaking....."

16 posted on 06/27/2019 11:04:44 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: gr8eman

https://en.wikipedia.org/wiki/Primate#Classification_of_living_primates


17 posted on 06/27/2019 11:06:26 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: BenLurkin

So many pro athletes are unhealthy?


18 posted on 06/27/2019 11:07:30 AM PDT by 9YearLurker
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To: BenLurkin

White Castle (long may it live).


19 posted on 06/27/2019 11:10:23 AM PDT by Category Four (Joy, Fun, the Joke Proper, and Flippancy ... Flippancy is the best of all.)
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To: Spruce

Good answer! Also drove agriculture...


20 posted on 06/27/2019 11:11:49 AM PDT by null and void (Stamp out philately!)
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