Posted on 10/23/2017 9:08:11 PM PDT by nickcarraway
Roughly 5 ¹/₂ million Americans are living with Alzheimer’s, a disease that ravages sufferers’ memories and, ultimately, stops their bodies from performing basic functions. There’s no cure, and not much that patients and their caregivers can do to stop the progression — but according to Joseph Jebelli, a neuroscientist and author of “In Pursuit of Memory: The Fight Against Alzheimer’s” (Little, Brown; out Oct. 31), hope is on the way. He estimates that there will be a medication to prevent the disease within the next 10 to 20 years.
“[The idea is to push] the disease back, by developing a drug that we can give to someone years before they start experiencing symptoms,” Jebelli tells The Post. Researchers can use biomarkers — certain signs of the disease visible in spinal fluid and blood — to determine who may need early treatment.
“It will change the course of the disease, pushing it back to the point where not only do they not experience any symptoms, but they’re dying naturally,” Jebelli says.
(Excerpt) Read more at nypost.com ...
The newest alleged prevention is drinking coffee - 4-5 cups a day, I think.
My mom, dad, and aunts drink/drank coffee all day long. In their 80s and 90s — minds as sharp as a tack, and put me to shame.
It’s like everything else, I suppose. A fad prevention will appear and in a couple years be replaced by another fad. I do believe there will be a cure in the near future.
One very interesting observation by a top researcher on schizophrenia..... People with schizophrenia do not get Alzheimer’s.
Evil rays from television sets?
You can prevent it NOW...by rejecting the very wrongheaded dietary guidelines that created the “crisis” to begin with. Eat avacados, coconut and olive oils, butter, eggs (WITH yolks). Avoid sugars, excessive carbs, margarine, pesticides. Avoid “low fat” diets in favor of low carb and low sugar diets.
One very interesting observation by a top researcher on schizophrenia..... People with schizophrenia do not get Alzheimer’s.
__________________
Yes they do.
The large cohort of schizophrenic baby boomers is now aging and Alzheimer’s is a prominent feature.
http://www.upmc.com/media/experts/Pages/david-a-lewis.aspx
David A. Lewis, MD UPMC Endowed Professor in Translational Neuroscience and Chair, Psychiatry, University of Pittsburgh Schools of the Health Sciences David A. Lewis, MD was named chair of the University of Pittsburgh Department of Psychiatry and Medical Director of the Western Psychiatric Institute and Clinic of UPMC in September 2009. A national expert in schizophrenia, Dr. Lewis’ research focuses on the neural circuitry of the prefrontal cortex and related brain regions and the alterations of this circuitry in schizophrenia.
Dr. Lewis is the UPMC Professor of Translational Neuroscience in the Department of Psychiatry, School of Medicine; professor of neuroscience in the School of Arts and Sciences; and director of the Translational Neuroscience Program at the University of Pittsburgh. In addition to his academic responsibilities, Dr. Lewis serves as director of a National Institute of Mental Health (NIMH) Conte Center for the Neuroscience of Mental Disorders at Western Psychiatric Institute and Clinic, which is focused on understanding the role of prefrontal cortical dysfunction in the pathophysiology of schizophrenia.
Dr. Lewis received his Bachelor of Arts in psychology and his medical degree from The Ohio State University. After completing residencies in internal medicine and psychiatry at the University of Iowa, Dr. Lewis received his research training at the Research Institute of the Scripps Clinic in California. He arrived in Pittsburgh in 1987 as associate professor of psychiatry and behavioral neuroscience. He has been the UPMC professor of translational neuroscience since 2006. An author of more than 300 scientific articles, Dr. Lewis serves as deputy editor of The American Journal of Psychiatry and a section editor of Neurobiology of Disease.
In 2007, he was appointed to the Institute of Medicine of the National Academy of Sciences for his contributions to the advancement of schizophrenia treatments and his efforts to bring the importance of this major public health issue to the forefront. He also has received the Leiber Prize from NARSAD, the Dean Award from the American College of Psychiatry and the Warren Award from the International Congress on Schizophrenia Research, each of which recognizes major contributions to advancing the understanding of schizophrenia.
Dementia as a complication of schizophrenia
P J de Vries, W G Honer, P M Kemp, P J McKenna
J Neurol Neurosurg Psychiatry 2001;70:588–596
Abstract
Objectives—Cognitive impairment is
known to occur in schizophrenia, and may
be marked in institutionalised patients.
The aim of this study was to determine
whether it ever warrants an additional
diagnosis of dementia.
Conclusions—Dementia in schizophrenia
seems to be a real entity with a neuropsychological
signature similar to that of
frontotemporal dementia. Functional but
not structural imaging abnormalities may
also be characteristic.
(J Neurol Neurosurg Psychiatry 2001;70:588–596)
The coincidental development of Alzheimer’s
disease, multi-infarct dementia, or cortical
Lewy body disease in some of the older patients
is diffcult to exclude with certainty during life,
and CT appearances may be deceptively
normal in Alzheimer’s disease.52
However, there are reasons for doubting that the patients
had any of these disorders: (a) Alzheimer’s disease
is rare in the presenile period; (b) medial
temporal lobe atrophy was no greater in this
series of patients than in schizophrenia as a
whole; (c) multi-infarct dementia would be
unusual in the absence of other evidence of
vascular disease; and (d) all three dementias
would be likely to progress rather than remain
static over periods of observation ranging from
2 to 10 years. One further dementia, frontotemporal
dementia, remains a realistic differential
diagnosis: this commonly presents in the
presenile period, may progress only slowly, and
may show functional imaging abnormalities
coupled with structural imaging appearances
which remain normal for a long time.53–55 A
counter argument, however, is that, on current
evidence, psychotic symptoms are uncommon
in frontotemporal dementia.55
Read the other replies to my comment for some illumination, as it’s rather academic. The fact is that humans have been curing ALL diseases naturally throughout this modern era but there’s no money to be made of a cure. This is the reality of our perverted system. Everyone mocks the conspiracy theories about the 1000 mpg carburetor and “big oil” but why can’t anyone grasp the reality of “big pharma” as a metaphor for 1. a medical establishment which no longer heals, 2. a government which found power in making its people dependent upon it via health?
To the point: It’s truly about inflammation, one of the key facets underlying my methodology outlined in my books. Feel free to freepmail me for more insight, but read the linked article very, very carefully and you’ll see that even researchers found the key to preventing Alzheimer’s yet are apparently intentionally-ignorant to see the forest through the trees.
Here it is in a nutshell: Everyone has genetic differences. The reason there are so many named diseases is due to the fact that each of us has genetic tendencies to develop certain impaired health symptoms, some of which get labeled as “diseases.” The smallest blood vessels in the body are capillaries, many of which are only large enough for single blood cells to traverse, reaching the core of our deepest organs, including the skin and, of course, the brain. Inflammation prevents bloodflow to these smallest blood vessels, but oxygen deprivation is easily adaptable by our bodies...the factor most researchers address.
Ask yourself: What is the other function of bloodflow?
What happens when your toilet backs up?
Read the article, research inflammation, research gut health and carefully consider the fact that your family has a genetic trait to express Alzheimer’s. The article may very well outline a treatment to facilitate restorative healing of the brain, but I’m dubious. What it does outline is how Alzheimer’s develops in the first place. It fails by refusing to concede that they may have found the CAUSE. When I read this article, I was literally screaming at my computer and the boneheaded researchers.
The reality is that some diseases have no after-the-fact “cure,” the damage wrought is too great. Someday we may very well have the ability to regrow organs damaged by cancer and other effects of impaired health, but once your brain has decayed, for most it’s just too late.
The only true “cure” is prevention, another major underpinning of my books.
Unfortunately, we as a species react best to a crisis; it is a human trait to be wilfully-ignorant of the many threats around us. I was, too, until my health declined to the point where I was bouncing off walls, having daily nosebleeds and couldn’t lift a gallon of milk. I cured my lifetime of seasonal allergies, adult cystic acne, arthritis, debilitating neck & back pain, carpal tunnel symptoms, hypothyroidism and over 50 other named impaired health symptoms.
I was just “lucky” that my genetics didn’t prescribe that my body express one of the more serious named diseases. I took my health recovery as a sign and invested the prior 4 years to write about how I could help others. The problem, I’ve found, is that most people don’t want to hear it and I’m now immersed in researching a different method of communication so I may better address broaching my methodology to those who willfully & ignorantly participate in our toxic western lifestyle until they get sick...the problem being that although my methodology is elegantly-simple, everyone is different and there is no single point fix, no pill, powder, elixir or “diet” which is prescribed for all.
If there were, everyone would be cured of “disease” today, including obesity. So here’s the rub: The solution is elegantly-simple, but it requires learned effort to read & understand the gravity of the environment posed to each & every one of us. We have created a toxic environment for our biology and those charged with safeguarding public health...don’t. Absent the desire of a person to invest effort, I have learned that most people simply don’t care about my approach, wilfully ignorant of the reality until they express symptoms which then grab their attention. There is a synergy of causes; thus, no single solution to outline. Nearly all people embrace one or 2 health approaches but fail to go all the way. The failure of my approach is that it mandates effort of the individual. It’s all-in or nothing. Cliche’, but true. The success of my methodology is that I believe it permits everyone to prevent many, if not most, of the scourge of diseases killing Americans & others in the developed world.
I concede that I’m weak on outreach and now investing time in learning communication skills. TedX is in my future, particularly now that I believe that I’ve had a breakthrough in explaining the human trait which causes people to block out the approach outlined by me and having been addressed by others in the past. Irony: I’m not the first to use my methods, but I believe that I’m the first to address health in the manner in which I prescribe in the books, as NOT A SINGLE ONE of my 1000+ references would have completely reversed my health condition and the multitude of impaired health symptoms...but every single reference had a bearing on the foundation of what became my methodology. There is likely a former MD and/or naturopath out there who might have pointed me down the path of healing, but I never met them or found their book even after thousands of hours of research.
THAT’s the value in what I’ve accumulated in research & writing.
https://newatlas.com/alzheimers-dementia-treatment-ultrasound/36510/
The simple answer is “remove the antagonists,” but it’s a bit more complicated than that. If it were simple to outline, it wouldn’t have required a collective 1000 pages between 3 books (soon to be 4, as Ill be spinning off some content into a standalone publication on psychology) to completely address the problem.
See my comment #49.
I am researching this topic right now to further clarify the statement in my notes.
While there are many journal articles on this topic, there are many loose definitions of types of dementia and also schizophrenia. I prefer physiological identification criteria over the more subjective DSM’s.
Thank you for challenging my statement as it is how I learn....
I agree. My mom is an ice cream demon. But at this point (going on 10 years) it makes her happy. Did it accelerate her disease? Perhaps.
If I had known this 15 years ago, could I have influenced her dietary choices? I doubt it. :(
Same with my mother in law. Lived on ice cream.
Sugar can utilize the thiamine or B-1 vitamin which in turn decreases activity in the dentate gyrus, which interacts with the hippocampus (inhibiting memory retrieval). It also inhibits the citric acid or Krebs Cycle from producing ATP aerobically and creates severe fatigue.
If she constantly consumes ice cream and sleeps upright in a chair rather than the bed, have her checked for a GE junction obstruction such as cancer. Another indication of this is a B-12 deficiency where she needs injections to stop pernacious anemia and/or depression. The cancer in the fundus (upper stomach near the GE junction) causes the parietal cells to not produce the intrinsic factor necessary to protect the B-12 as it goes through the stomach acid which destroys it.
Ice cream is considered a liquid and can find a path through a constricted esophageal sphincter while solid foods will create severe coughing and blockage.
Very true. Now, knowing she doesn’t have a ton of t8me ahead of her here, I give her one dessert a day. But it is her choices 20 yearsa fo that would have made any different, if it is diet.
And I’m not sure that starving or low cal will help. Holocaust survivors as well as perpetually dieting women still get it. Eating the bad fats seems to give you inflammation and heart disease but no huge correlation to Alz. There could theoretically be some infectious agent that we haven’t discovered yet... I’d like more research to go into prevention rather than some drug. Who doesn’t get it, and why not?
Our brains are fat fed. I have low blood sugar and my brain is the first sign. I can’t eat sugar so I eat fat.
I believe it is stress that causes the problems.
question, did they also have rheumatoid arthritis? It’s in my family too.
Somewhat true but mostly BS. If you eat a “heart smart” diet and protocol there are benefits - “some” but for many there are still no benefits for arresting the disease.
Yes, as one other comment said, telling me it’ll be fixed with a (billions dollar windfall) medication makes me laugh.
The answer is probably out there, and perhaps a multi factorial one. But a billion dollar bandaid is not the answer, unless you’re a shareholder of the winning drug company.
There has been research on support supplements like CoQ10 and Omega-3. Also, raising blood ketones via diet and MCT oil intake.
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