Breakthrough device heals organs with a single touch

ScienceDaily ^ | August 7, 2017 | Ohio State University Wexner Medical Center

[buckalfa]

Researchers at The Ohio State University Wexner Medical Center and Ohio State's College of Engineering have developed a new technology, Tissue Nanotransfection (TNT), that can generate any cell type of interest for treatment within the patient's own body. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells.

Results of the regenerative medicine study published in the journal Nature Nanotechnology.

"By using our novel nanochip technology, injured or compromised organs can be replaced. We have shown that skin is a fertile land where we can grow the elements of any organ that is declining," said Dr. Chandan Sen, director of Ohio State's Center for Regenerative Medicine & Cell Based Therapies, who co-led the study with L. James Lee, professor of chemical and biomolecular engineering with Ohio State's College of Engineering in collaboration with Ohio State's Nanoscale Science and Engineering Center.

Researchers studied mice and pigs in these experiments. In the study, researchers were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg, and by the second week, the leg was saved. In lab tests, this technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.

"This is difficult to imagine, but it is achievable, successfully working about 98 percent of the time. With this technology, we can convert skin cells into elements of any organ with just one touch. This process only takes less than a second and is non-invasive, and then you're off. The chip does not stay with you, and the reprogramming of the cell starts. Our technology keeps the cells in the body under immune surveillance, so immune suppression is not necessary," said Sen, who also is executive director of Ohio State's Comprehensive Wound Center.

TNT technology has two major components: First is a nanotechnology-based chip designed to deliver cargo to adult cells in the live body. Second is the design of specific biological cargo for cell conversion. This cargo, when delivered using the chip, converts an adult cell from one type to another, said first author Daniel Gallego-Perez, an assistant professor of biomedical engineering and general surgery who also was a postdoctoral researcher in both Sen's and Lee's laboratories.

TNT doesn't require any laboratory-based procedures and may be implemented at the point of care. The procedure is also non-invasive. The cargo is delivered by zapping the device with a small electrical charge that's barely felt by the patient.

"The concept is very simple," Lee said. "As a matter of fact, we were even surprised how it worked so well. In my lab, we have ongoing research trying to understand the mechanism and do even better. So, this is the beginning, more to come."

Researchers plan to start clinical trials next year to test this technology in humans, Sen said.

Funding for this research was provided by Leslie and Abigail Wexner, Ohio State's Center for Regenerative Medicine and Cell-Based Therapies and Ohio State's Nanoscale Science and Engineering Center.

[mewzilla]

Holy mackerel.

[hattend]

Who the hell is that?

[GreenHornet]

I’m just glad they didn’t beam up Rosie O’Donnell!!

The Transporter beam isn't wide enough.

[babygene]

bookmarked

[ETL]

Benny Hinn: Net Worth $42 Million

Toufik Benedictus "Benny" Hinn is a televangelist originally born in Jaffa, Israel and was raised in the Eastern Orthodox tradition. He converted to Pentecostalism as a teenager in Toronto and became so immersed in the faith that it actually concerned his family. Despite dropping out of high school, he went on to found the Orlando Christian Center in 1983 and began professing his faith healing abilities. 

Hinn’s teachings are characterized as charismatic Christianity, with an emphasis on spiritual gifts and the prosperity gospel. He is best known for hosting “Miracle Crusades” —faith healing summits—generally held in large stadiums in major cities, which are later broadcast worldwide on his television program, "This Is Your Day," on the Trinity Broadcasting Network. Hinn has been scrutinized for personal use of church-owned luxury goods and a lack of financial oversight on the ministries' boards, which are often populated with family and friends of the televangelist.

http://www.beliefnet.com/faiths/christianity/8-richest-pastors-in-america.aspx?p=4

[RedwM]

My baby sister is dying from liver and kidney failure right beside me. I would volunteer her to be a guinea pig.

[ETL]

Very sorry to hear that, Friend. Hopefully her condition will somehow improve and she’ll be with us for many more years to come.

[bar sin·is·ter]

Worked for me bro...

[hattend]

Goa’uld healing device.

[Bigg Red]

:)

[ifinnegan]

:)

[huldah1776]

“Not if God is just!”

Ironic. His justice against this pre-born genocidal nation is a given. His mercy may give us a reprieve with legal repentance and spiritual revival.

[SaveFerris]

And the tank was nowhere big enough.

Nor was the Transparent Aluminum strong enough.

[RedwM]

Thank You for your kind thoughts. Thank GOD for my Wife.